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Quentin Smith

@qmsmith

Postdoctoral Research Fellow at Boston Children's Hospital & Harvard Medical School in the Ha and Farnung labs. PhD at Imperial College London in the Rueda lab.

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09.12.2024
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Latest posts by Quentin Smith @qmsmith

🚨 2 WEEKS remaining until the Abstract Deadline on 22nd March 2026!

πŸ”¬ We’re calling all early career researchers to apply as soon as possible to be considered for an oral presentation!

πŸ”— www.grc.org/single-molec...

#biology #biophysics #single-molecule #microscopy #ECR

09.03.2026 15:37 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

It’s finally out! 😊

24.02.2026 10:23 πŸ‘ 10 πŸ” 2 πŸ’¬ 2 πŸ“Œ 0

🚨 4 WEEKS remaining until the Abstract Deadline on 22nd March 2026!

πŸ”¬ We’re calling all early career researchers to apply as soon as possible to be considered for an oral presentation!

πŸ”— www.grc.org/single-molec...

#biology #biophysics #single-molecule #microscopy #ECR

20.02.2026 17:36 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Research Group Leader Tenure Track - Structural Studies - LMB 2775 - Medical Research Council Location: Cambridge. Vacancy: Research Group Leader Tenure Track - Structural Studies - LMB 2775. Closing Date: 16/03/2026, 23:55

Please spread the word: the Structural Studies Division @mrclmb.bsky.social is looking for a new tenure-track, independent group leader with an exciting plan in any area of Structural (Molecular & Cell) biology, in discovery biology and/or methods development. πŸ₯³

mrc.tal.net/vx/mobile-0/...

16.02.2026 12:09 πŸ‘ 83 πŸ” 106 πŸ’¬ 1 πŸ“Œ 3
Photo of (left to right) Mark Searcey, Fuad Muhamud, Paul Skelton and ZoΓ« Waller

Photo of (left to right) Mark Searcey, Fuad Muhamud, Paul Skelton and ZoΓ« Waller

Congratulations to Fuad Mahamud for passing his PhD viva (in his DNA jumper no less). Many thanks to Prof Mark Searcey and Vijay Chudasama for examining!

13.02.2026 19:08 πŸ‘ 5 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

#scientists, take a second to fully appreciate the @pdbeurope.bsky.social and @rcsbpdb.bsky.social and imagine live without them.

12.02.2026 11:36 πŸ‘ 29 πŸ” 6 πŸ’¬ 0 πŸ“Œ 0

Congratulations Kelly! πŸ₯³

10.02.2026 14:39 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Look at this πŸ™‚ #CryoEM

Structural basis for CTCF-mediated chromatin organization by @lucas.farnunglab.com @voslab.org

www.biorxiv.org/content/10.6...

09.02.2026 08:32 πŸ‘ 77 πŸ” 18 πŸ’¬ 4 πŸ“Œ 0
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πŸ§ͺ🧬New preprint We present cryo-EM structures of reconstituted CTCF–nucleosome complexes, showing CTCF dimerization drives nucleosome oligomerization into defined higher-order assemblies. Disrupting CTCF–CTCF interfaces in mESCs reduces looping and impairs differentiation. tinyurl.com/CTCF-nucleos...

09.02.2026 12:54 πŸ‘ 123 πŸ” 52 πŸ’¬ 4 πŸ“Œ 3
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Happy to share part of my postdoctoral work at the @lucas.farnunglab.com lab. Great collaboration with @voslab.org and @andersshansen.bsky.social. β€œStructural basis for CTCF-mediated chromatin organization” www.biorxiv.org/content/10.6...

09.02.2026 15:22 πŸ‘ 30 πŸ” 10 πŸ’¬ 0 πŸ“Œ 0

🚨 6 WEEKS remaining until the Abstract Deadline on 22nd March 2026!

πŸ”¬ We’re calling all early career researchers to apply as soon as possible to be considered for an oral presentation!

πŸ”— www.grc.org/single-molec...

#biology #biophysics #single-molecule #microscopy #ECR

06.02.2026 20:08 πŸ‘ 4 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

πŸ—£οΈ Keynote Speaker: @sulianamanley.bsky.social

πŸ‘₯ Mentoring Session: Careers Across Biophysics featuring @valdavinson.bsky.social @timcraggs.bsky.social @sulianamanley.bsky.social @esisamakis.bsky.social

πŸ“ˆ Selected talk and poster presenters: You!

β˜€οΈ Please repost, share and we'll see you in June!

22.01.2026 15:18 πŸ‘ 5 πŸ” 3 πŸ’¬ 0 πŸ“Œ 1
Visual advertisement providing details for the 2026 Single Molecule Approaches to Biology GRS in Les Diablerets, Switzerland in June 27-28, 2026. Two-day event for early-career single-molecule biophysicists, with a keynote session, 12 selected talks, 2 poster sessions, and mentorship component. For more information contact Alba or Quentin or see the official GRS website.

Visual advertisement providing details for the 2026 Single Molecule Approaches to Biology GRS in Les Diablerets, Switzerland in June 27-28, 2026. Two-day event for early-career single-molecule biophysicists, with a keynote session, 12 selected talks, 2 poster sessions, and mentorship component. For more information contact Alba or Quentin or see the official GRS website.

πŸ”¬ Calling all early-career researchers (ECRs) for the GRS Single Molecule Approaches to Biology!

🌎 Location: Les Diablerets, Switzerland

πŸ“† Save the date: June 27-28, 2026

πŸ”— More information: www.grc.org/single-molec...

#biology #biophysics #single-molecule #microscopy #ECR

22.01.2026 15:18 πŸ‘ 5 πŸ” 6 πŸ’¬ 1 πŸ“Œ 3

I’m very pleased to share our work looking at what controls condensin II cell-cycle dependant activity; a great collaboration with @eugenekimlab.bsky.social, @damlatetiker.bsky.social, Kyle Muir and Kumiko Samejima
www.biorxiv.org/content/10.6...

04.02.2026 15:57 πŸ‘ 28 πŸ” 12 πŸ’¬ 2 πŸ“Œ 0

Presenting our research tomorrow @aicc-ireland.bsky.social Please join via Zoom!

29.01.2026 16:46 πŸ‘ 8 πŸ” 3 πŸ’¬ 0 πŸ“Œ 1

I’m honored to be part of the next GRS Single Molecule Approaches to Biology, thanks Chairs @qmsmith.bsky.social and Alba Gomez Segalas for organizing this great event! The GRS is a wonderful opportunity for young scientists to share their exciting science and build communities. See you there!

23.01.2026 11:21 πŸ‘ 5 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0

πŸ—£οΈ Keynote Speaker: @sulianamanley.bsky.social

πŸ‘₯ Mentoring Session: Careers Across Biophysics featuring @valdavinson.bsky.social @timcraggs.bsky.social @sulianamanley.bsky.social @esisamakis.bsky.social

πŸ“ˆ Selected talk and poster presenters: You!

β˜€οΈ Please repost, share and we'll see you in June!

22.01.2026 15:18 πŸ‘ 5 πŸ” 3 πŸ’¬ 0 πŸ“Œ 1
Visual advertisement providing details for the 2026 Single Molecule Approaches to Biology GRS in Les Diablerets, Switzerland in June 27-28, 2026. Two-day event for early-career single-molecule biophysicists, with a keynote session, 12 selected talks, 2 poster sessions, and mentorship component. For more information contact Alba or Quentin or see the official GRS website.

Visual advertisement providing details for the 2026 Single Molecule Approaches to Biology GRS in Les Diablerets, Switzerland in June 27-28, 2026. Two-day event for early-career single-molecule biophysicists, with a keynote session, 12 selected talks, 2 poster sessions, and mentorship component. For more information contact Alba or Quentin or see the official GRS website.

πŸ”¬ Calling all early-career researchers (ECRs) for the GRS Single Molecule Approaches to Biology!

🌎 Location: Les Diablerets, Switzerland

πŸ“† Save the date: June 27-28, 2026

πŸ”— More information: www.grc.org/single-molec...

#biology #biophysics #single-molecule #microscopy #ECR

22.01.2026 15:18 πŸ‘ 5 πŸ” 6 πŸ’¬ 1 πŸ“Œ 3

We have an opening for a research support officer. Come and join us! Please share.

22.12.2025 12:09 πŸ‘ 17 πŸ” 22 πŸ’¬ 0 πŸ“Œ 0
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Application to speak in the Fragile Nucleosome series Thank you for your interest in our seminar series! We use a variety of different session formats but, in general, trainees can plan for a ~15 min talk + 5min Q/A and PIs can plan for a ~25min talk +...

Do you have an exciting new chromatin/transcription story that you'd like to share with the #FN community?

Fill out this form to be considered for a talk in our Jan-June 2026 schedule! forms.gle/TBi38UgYxPAB...

Please repost and share!

24.11.2025 13:50 πŸ‘ 27 πŸ” 20 πŸ’¬ 0 πŸ“Œ 3
UCL – University College London UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

We are recruiting! PDRA to work on a BBSRC funded position with Prof. Yiliang Ding and Dr. Tim Craggs. We are looking for someone with experience with cell culture and gene expression analysis - Please do share. Happy to answer any questions. Details below:
www.ucl.ac.uk/work-at-ucl/...

16.12.2025 11:49 πŸ‘ 3 πŸ” 2 πŸ’¬ 0 πŸ“Œ 1

Exciting project!Great opportunity!

16.12.2025 15:37 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

It’s an honor to be awarded the LMS PhD Prize, I am truly grateful for the kind comments made by my examiners and for the MRC LMS acknowledging my graduate studies as an achievement! πŸ₯³

17.12.2025 20:43 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Quentin Smith awarded LMS PhD Prize We’re delighted to announce that Quentin Smith has been awarded the latest LMS PhD Prize for his outstanding thesis and viva performance.

Congratulations to @qmsmith.bsky.social for winning the LMS PhD Prize in recognition of his outstanding thesis and viva performance!

We wish him the best of luck in his new role as a joint postdoctoral research fellow at Boston Children's Hospital and Harvard Medical School.

17.12.2025 15:17 πŸ‘ 6 πŸ” 1 πŸ’¬ 0 πŸ“Œ 1

Happy to see our latest work online. Here we present a new method for microsecond time-resolved cryo-EM based on jet vitrification! Details in the 🧡 below... we hope you enjoy reading! (Hint, there's some fun videos...) #cryoEM #structuralbiology

22.11.2025 11:26 πŸ‘ 26 πŸ” 6 πŸ’¬ 1 πŸ“Œ 0
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Cryo-EM reveals open and closed Asgard chromatin assemblies Ranawat et al. show the cryo-EM structures of Asgard archaeal chromatin assemblies, revealing that the histone HHoB assembles into both compact closed and extended open hypernucleosomes. The closed co...

Let’s wrap things up: my commentary on the Asgard hypernucleosomes.

Congratulations to all the authors of the paper 🍾!

kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...

Cryo-EM reveals open and closed Asgard chromatin assemblies: Molecular Cell www.cell.com/molecular-ce...

20.11.2025 16:23 πŸ‘ 39 πŸ” 13 πŸ’¬ 0 πŸ“Œ 1

Thank you, Daniela, @danielabarilla.bsky.social, for a wonderful commentary! πŸ€—πŸ€— More spotlight on the Asgards and their chromatin! ❀️ #archaea #chromatin

20.11.2025 17:53 πŸ‘ 21 πŸ” 7 πŸ’¬ 0 πŸ“Œ 0
Me in front of the ABRCMS sign

Me in front of the ABRCMS sign

16 (! What?) years ago I went to my first ABRCMS and was welcomed and encouraged to pursue my scientific dreams. I met folks that provided direct feedback on my graduate school applications and served a pivotal role in my career. I am honored return and give back again as faculty.
#ABRCMS2025

20.11.2025 21:33 πŸ‘ 59 πŸ” 7 πŸ’¬ 1 πŸ“Œ 0
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Happy to share our latest preprint.

We uncover a previously uncharacterised and evolutionarily conserved chromatin architecture in premeiotic gonadal germ cells, revealed through integrated cytological and high-resolution Hi-C approaches.

www.biorxiv.org/content/10.1...

ThreadπŸ§΅πŸ”½

18.11.2025 16:57 πŸ‘ 17 πŸ” 6 πŸ’¬ 1 πŸ“Œ 0
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Please join us on November 20th! We are very grateful for our first sponsorship - Molecular Instrument!

18.11.2025 19:39 πŸ‘ 1 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0