Pierre Vanderhaeghen

New approach methodologies: Don’t throw the baby out with the bathwater The NIH has recently called for expanding use of new approach methodologies (NAMs) to reduce use of animals in research. Arany discusses the need not to forget the irreplaceable aspects of animal rese...

Should go without saying, but saying so becomes urgent: New approach methodologies: Don’t throw the baby out with the bathwater: Cell Metabolism www.cell.com/cell-metabol...

Scientists have seen Asgard archaea crawling for the first time. When it comes to the origin of eukaryotes, this is like seeing a feathered dinosaur in the wild. (Video courtesy of Philipp Ralder)

Neuroscience has a species problem If neuroscience is serious about building general principles of brain function, cross-species dialogue must become a core organizing principle.

www.thetransmitter.org/animal-model...

Cover of the December 1996 issue of Development that describes the results of The Big Screen.

Published 30 years ago, 'The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio' by the Nüsslein-Volhard Lab highlighted the arduous work that took place during 'The Big Screen'. In total, 1163 mutants were described. #ZebrafishFunFacts 🧪

Happy International Day of Women and Girls in Science! 🧪 Don't forget to send in your nominations for the FEBS | EMBO #WomenInScience Award.

Deadline: 15 May

Read more:
https://www.embo.org/the-embo-communities/febsembo-women-in-science-awardees/nominate-for-the-women-in-science-award/
#award

Congratulations Fiona!

Décès de Jean Rossier, Président passionné de Parole et Musique L’actualité de l’opéra : Décès de Jean Rossier, Président passionné de Parole et Musique

Décès de Jean Rossier, Président passionné de Parole et Musique :
www.olyrix.com/articles/act...

There's still time to apply to be a 2026 @dev-journal.bsky.social Pathway to Independence fellow

For those about to apply for their first independent academic position, the programme offers

- mentoring
- leadership training
- profile rising
- networking

journals.biologists.com/dev/pages/pi...

European Synapse Meeting 2026 21-23 October 2026, Leuven, Belgium Supported by VIB Training & Conferences

Book the dates Oct 21-23 2026 of upcoming exciting eurosynapse meeting in Leuven! www.vibconferences.be/events/europ...

Join us this May to explore the biological mechanisms of mental health challenges and treatment strategies. Apply by January 31: lakeconferences.org

🎉 Proud moment for our Center
Pierre Vanderhaeghen received the 2025 Fyssen Foundation International Prize, also awarded this year to Franck Polleux (@columbiauniversity.bsky.social) for work on the neurobiological foundations of human cognition. 🧠🏆
Congratulations!
#FyssenPrize #Neuroscience #VIB

Prix international 2025 - International Prize 2025 - fyssen Deux lauréats pour le Prix international de la Fondation Fyssen La Fondation Fyssen a le plaisir d’annoncer que le Prix international est exceptionnellement attribué à deux lauréats cette année. Le pr...

Delighted to be awarded the 2025 International Prize from the @fondationfyssen.bsky.social jointly with my long time collaborator @vanderhaeghenp2.bsky.social for our work on the 'Neurobiological foundations of human cognition': www.fondationfyssen.fr/deux-laureat...

La Fondation Fyssen a le plaisir d’annoncer que le Prix international 2025, consacré au thème « Fondements neurobiologiques de la cognition humaine », est attribué à Franck Polleux et Pierre Vanderhaeghen.
@franckp.bsky.social @vanderhaeghenp2.bsky.social
Rdv en juin 2026 pour la remise de prix !

Please check out and RT this new position for an exciting collaborative project with @boninlab.bsky.social and @franckp.bsky.social on the links between human-specific mechanisms and neurodevelopmental disorders in cortical circuits.

Postdoctoral Fellow / PhD Student in Systems Neuroscience - VIB The Laboratory of Cortical Information Processing | Vision to Action at NERF (www.nerf.be) invites applications for a Postdoctoral Fellow or PhD Student to work on a new research project funded by the...

Please repost widely. @vanderhaeghenp2.bsky.social and I are hiring a postdoc with expertise in sensory physiology and in vivo circuit imaging/manipulation. The project centers on human-specific brain development and SYNGAP1-related disorders. Call closing soon—apply ASAP
jobs.vib.be/j/119852/pos...

Protein tug-of-war controls pace of synaptic development, sets human brains apart Human-specific duplicates of SRGAP2 prolong cortical development by manipulating SYNGAP, an autism-linked protein that slows synaptic growth.

Nice cover of our work linking SRGAP2/SYNGAP1 synaptic neoteny and ID/ASD with @blibep.bsky.social @benvermaercke.bsky.social @franckp.bsky.social @boninlab.bsky.social @cecilecharrier.bsky.social www.thetransmitter.org/spectrum/pro...

Very sad news, John Gurdon has died.

A developmental biologist's developmental biologist, Nobel prize winner

His work is the foundation of much of today's dev & stem cell bio.

An inspiration to many, including me. Always asking questions & wanting the answers

www.magd.cam.ac.uk/news/profess...

Cell-type-specific dysregulation of gene expression due to Chd8 haploinsufficiency during mouse cortical development Yim et al. use single-cell transcriptomics to elucidate the molecular outcomes of Chd8 haploinsufficiency in the mouse cortex. Their results provide insight into dynamic, cell-type-biased transcriptio...

Out in Cell Genomics: A comprehensive analysis of the cell-type-specific effects of CHD8 loss of function on gene expression in the embryonic and juvenile mouse cortex. Thread 🧵:
www.cell.com/cell-genomic...

Species-specific Rates of Fatty Acid Metabolism Set the Scale of Temporal Patterning of Corticogenesis through Protein Acetylation Dynamics Developmental processes display temporal differences across species, leading to divergence in organ size and composition. In the cerebral cortex, neurons of diverse identities are generated sequential...

New from the lab: Fatty Acid Metabolism Sets the Species-specific Tempo of Cortical Development through Protein Acetylation Dynamics. Led by amazing trio: @ryo2iwata.bsky.social , Isabel Gallego, @emirerkol.bsky.social, together with @steinaerts.bsky.social , @fendtlab.bsky.social

Mitochondrial origins of the pressure to sleep - Nature Research on Drosophila neurons shows links between the need to sleep and aerobic metabolism, indicating that the pressure to sleep may have a mitochondrial origin.

Beautiful and inspiring work from Gero Miesenböck and colleagues www.nature.com/articles/s41...

May has been quite the month…

The #EvoDevoConference was a blast 💥

Thanks to all participants and organizers for your engagement!

@mdiazcuadros.bsky.social @bassemh.bsky.social @vanderhaeghenp2.bsky.social

📸
(1/2)

Drosophila Genetic Database The Drosophila Genetic Database, FlyBase, is on the brink of collapse due to the sudden termination of the FlyBase NIH grant, which includes salaries for 5 literature curators based at the University ...

Flybase lost all of the NIH support overnight - it is a disaster for the community. Please consider donating. I just did! www.philanthropy.cam.ac.uk/give-to-camb...

Sequential and independent probabilistic events regulate differential axon targeting during development in Drosophila melanogaster Nature Neuroscience - The developmental origin of behavioral individuality is unclear. The authors show that a temporal sequence of genetically encoded stochastic mechanisms explains variation in...

Hot off the press:
The excellent Maheva Andriatsilavo and colleagues show how a temporal sequence of stochastic molecular mechanisms allow the emergence of stereotyped individualised neuronal circuits. Just published in Nature Neuroscience:
rdcu.be/ek010

wonderful - congratulations @debbysilver.bsky.social !!

Fantastic opportunity for neuroscience research.
The ROGER DE SPOELBERCH Prize for a basic or clinical research project in the areas of neurodegenerative diseases or psychiatric disorders.
750.000 EUR - Deadline JUNE 30 2025.
www.fondation-roger-de-spoelberch.ch/en/roger-de-...

VIB.AI International PhD Call 2025 The VIB.AI International PhD Call 2025 is now open. We invite applicants from around the world to join an interdisciplinary research environment at the interface of AI, computational biology, and life...

Fantastic PhD opportunities at the intersection of machine learning and biology. Come join us at @vibai.bsky.social! More details at: vib.ai/en/vibai-int...

Join us in Engelberg, Switzerland, for an exciting #EMBO workshop on #mitochondria in the nervous system #EMBOmitoNervousSys!
Great speaker line up and opportunities for short talks from early career scientists.
Submit your abstract until May 30st!
@jcourchet.bsky.social @tatjanakleele.bsky.social

I'm thrilled to be co-organizing the very first EMBO Workshop bridging mitochondria and brain research - a powerhouse of science, ideas, and amazing speakers! 🧠🔬

📅 registration closes MAY 30th, so don’t wait to snag your spot!

Stay tuned - more updates about the topics and speakers coming soon! 🎙️

It’s out! The first paper from my postdoc – and first from the @bhadurilab.bsky.social – is now live @natneuro.nature.com . 🧠✨

Using a new meta-atlas generation strategy, we identified functional gene networks that more fully explain how cell types are formed in the human cortex. (1/13)