Anna Schulten

Call for papers! To celebrate the upcoming edition of the Chromatin and Transcription: FLC and beyond II meeting in Madrid, I am co-editing with the great @jiquesta.bsky.social
and Prof Zhe Wu from @sustech.bsky.social
a Research topic for @frontiersin.bsky.social
Plant Science (1/n)...

Postdoctoral Researcher (Dr Miguel Montez) | John Innes Centre An exciting opportunity has arisen for a Postdoctoral Researcher to join the Wellcome Trust project led by Dr Miguel Montez and hosted within the Dodd Group at the John Innes Centre.

📣 Looking for a 3-Year Postdoc @johninnescentre.bsky.social to join my Wellcome project.

This is a highly interdisciplinary project that explores chromatin dynamics in 🌱 plant responses across timescales, from circadian rhythms to seasonal changes

📅 Closes on 10 Dec.
www.jic.ac.uk/vacancies/36...

1/ 🚀 AEBP2 isn’t what we thought.

You were told that AEBP2 promotes PRC2 activity on chromatin.

We found the opposite: the most prevalent AEBP2 isoform inhibits PRC2 activity.

👉 surl.li/cgwqcq

A thread 🧵

Our paper on VEL-dependent polymerization is featured on the cover of this month's issue of @cp-molcell.bsky.social 🎉 The cover art was created by my talented friend Awesta - the result of hours of brainstorming together over video. Great fun teaming up for this!

Professor Yiliang Ding outside the John Innes Centre

NEWS - Professor Yiliang Ding awarded prestigious Royal Society Faraday Discovery Fellowship

These long-term @royalsociety.org awards are worth £8m over 10 years to support exceptional mid-career research leaders in the UK. Congratulations @yiliangding.bsky.social 👏

👉 www.jic.ac.uk/press-releas...

VEL-dependent polymerization maintains the chromatin association of Polycomb proteins for the switch to epigenetic silencing Schulten et al. show that VEL polymerization domains produce higher-order protein assemblies to maintain chromatin association of Polycomb proteins, enabling a stable epigenetic switch at the floral r...

Excited to share the paper from my work in the Dean lab @johninnescentre.bsky.social out now in @cp-molcell.bsky.social. Huge thanks to all the co-authors - it was a great collaborative effort! Watch out for the associated cover artwork coming out next week 🎉 www.cell.com/molecular-ce...

PRC2-mediated repression of PIF4 targets beyond the on/off switch of gene expression In this issue of Developmental Cell, Osborne et al. report that the angiosperm-specific polycomb repressive complex 2 (PRC2) subunit VERNALIZATION 2 (VRN2) regulates leaf growth by stable deposition o...

The final version of our paper showing VRN2-PRC2 mediated control of PIF4 signalling is now published in the latest issue of Developmental Cell @cellpress.bsky.social. Many thanks to Zhe Wu for writing an accompanying Preview piece summarising the work, here: www.cell.com/developmenta...

Caroline Dean sitting on a bench in front of some greenery.

The new issue of @newphyt.bsky.social features a profile of Caroline Dean:

👉 nph.onlinelibrary.wiley.com/doi/10.1111/...

#PlantScience #PlantEpigenetics #PlantLuminaries

Big congratulations to @kellythd-nguyen.bsky.social 👍👍👍Super beautiful structure👍👍👍Very happy to contribute some RNA structure work to this great collaboration😊 @johninnescentre.bsky.social @mrclmb.bsky.social

Just dropping this here in case anyone is interested in joining 🙃

VRN2-PRC2 facilitates light-triggered repression of PIF signaling to coordinate growth in Arabidopsis Osborne et al. show that the angiosperm-specific PRC2 subunit VRN2 is enriched in hypoxic regions of the Arabidopsis shoot, where it is required for stable deposition of H3K27me3 in key PIF4 target ge...

Happy to see our latest paper by @drosborneplantsci.bsky.social et al out today in Developmental Cell @cellpress.bsky.social! We identify a role for VRN2-PRC2 in regulating light-responsive growth in Arabidopsis through the conditional epigenetic repression of PIF signalling. tinyurl.com/swbyff24

Our paper has been published! We used in vivo single-particle tracking to demonstrate that the assembly of core FCA oligomers into functional macromolecular condensates.
Thanks to all the authors and colleagues!

In vivo single-particle tracking by Geng-Jen Jang, Caroline Dean et al reveals the modular assembly of #Arabidopsis gene expression regulator FLOWERING CONTROL LOCUS A from oligomers into molecular condensates competent for RNA 3’-processing
www.embopress.org/doi/full/10....

Cold-induced nucleosome dynamics linked to silencing of Arabidopsis FLC Temperature influences nucleosome dynamics, and thus chromatin, to regulate gene expression. Such mechanisms underlie the epigenetic silencing of Arabidopsis FLOWERING LOCUS C (FLC) by prolonged cold....

We are happy to share our work on local #nucleosome dynamics integrating #temperature inputs into an #epigenetic switching mechanism.

⚠️ Preprint alert!!
www.biorxiv.org/content/10.1...

I've written a commentary for Cell Systems arguing that biology needs to find a way to communicate its complexity from the outset, rather than starting with simple but misleading narratives.
It's free to view and download here (until 1 April).
authors.elsevier.com/a/1karS8YyDf...