Annie Newell-Fugate's Avatar

Annie Newell-Fugate

@annien-f

Scientist. Veterinarian. Educator. Mentor. Studies the effects of androgens and estrogens in metabolism. Conservationist and lover of nature. Seeker of the truth in all matters. https://www.newell-fugatelaboratory.com/

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11.01.2025
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Latest posts by Annie Newell-Fugate @annien-f

NOT-OD-24-110: Notice of Legislative Mandates in Effect for FY 2024 NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Notice of Legislative Mandates in Effect for FY 2024 NOT-OD-24-110. NIH

On changes to #NIH indirect rates, there is a law in place that prohibits NIH from making such changes without the approval of Congress. See Division D, Title II Section 224 of The Further Consolidated Appropriations Act, 2024 (Public Law No: 118-47) grants.nih.gov/grants/guide...

08.02.2025 00:56 πŸ‘ 3607 πŸ” 1471 πŸ’¬ 78 πŸ“Œ 239
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Scientists globally are racing to save vital health databases taken down amid Trump chaos The mass-archiving effort is in response to the US Centers for Disease Control and Prevention removing some of its web pages.

🧬🦠🧠πŸ₯ΌπŸ§ͺπŸ“ˆπŸŸ¦
@ebi.embl.org:

Many scientists are worried that vital biomedical data housed in U.S. government databases is at risk.

Which aspects of NCBI are mirrored on EMBL-EBI?
Do you plan to back up more U.S. data?

@altcdc.bsky.social
@altnih4science.bsky.social

www.nature.com/articles/d41...

07.02.2025 17:32 πŸ‘ 59 πŸ” 45 πŸ’¬ 5 πŸ“Œ 6

So sorry

06.02.2025 08:42 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Aerobic exercise decreases the number and transcript expression of inflammatory M1 macrophages and CD8+ T cells in the epicardial adipose tissue of female pigs Background: Epicardial adipose tissue (EAT) regulates coronary artery function via lipid metabolism and immune cell recruitment. Increased EAT is a risk factor for coronary artery disease (CAD), but a...

I am excited to share a pre-print that continues our work on the effects of exercise as opposed to a sedentary lifestyle on the epicardial adipose tissue of females.

www.biorxiv.org/content/10.1...

04.02.2025 19:04 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

So well written and so true. Thanks for sharing.

02.02.2025 14:04 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

I really hope this isn’t the case…

28.01.2025 02:47 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Horrific

28.01.2025 02:34 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Our country is hailed worldwide for our technical and scientific ingenuity

But it is federal grants that serve as the engine of innovation.

Pausing scientific grantmaking β€” by NSF, NIH, and more β€” is NOT a recipe for American greatness.

Consider reminding your senators & reps of this fact.

27.01.2025 23:33 πŸ‘ 155 πŸ” 64 πŸ’¬ 4 πŸ“Œ 5
That bright spot is a plastic-filled cell stuck in a blood vessel (the otherwise dark channel) for a week. Credit: Huang et al./Science Advances (2025)

That bright spot is a plastic-filled cell stuck in a blood vessel (the otherwise dark channel) for a week. Credit: Huang et al./Science Advances (2025)

Microplastics are everywhereβ€”including inside us. And that's not awesome, given that new research in mice finds they can mess up blood flow in the brain. That and more of the best from @science.org and science in this edition of #ScienceAdviser: www.science.org/content/arti... πŸ§ͺ

25.01.2025 20:49 πŸ‘ 488 πŸ” 107 πŸ’¬ 16 πŸ“Œ 7
Amazon Best Sellers: Best Books Discover the best books in Amazon Best Sellers. Find the top 100 most popular Amazon books.

Top selling books on Amazon this week…a telling story of our times.
#1984 #animalfarm #farenheit451 #wheressartrenoexit

25.01.2025 14:06 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Educate the public.
Educate the public.
Educate the public.

23.01.2025 14:53 πŸ‘ 153 πŸ” 36 πŸ’¬ 1 πŸ“Œ 1
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Trump hits NIH with β€˜devastating’ freezes on meetings, travel, communications, and hiring Researchers facing

Wadman and Kaiser are on it, over at ScienceInsider at the glam mag

Trump hits NIH with β€˜devastating’ freezes on meetings, travel, communications, and hiring | Science | AAAS www.science.org/content/arti...

23.01.2025 00:00 πŸ‘ 48 πŸ” 32 πŸ’¬ 4 πŸ“Œ 6

Yes cholesterol rises in association with menopause in women. Mostly LDL though and not total cholesterol. Keep in mind that cholesterol for steroid synthesis is very different from the lipoproteins we measure as β€œcholesterol” in the lab. Lipoproteins have triglycerides, proteins and cholesterol

23.01.2025 00:05 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

This has paused all study sections to review grants. In essence, the main funder of all biomedical research in the country will grind to a hault which will grind life saving biomedical research to a hault.

22.01.2025 22:24 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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NIH In Your State - United For Medical Research Select a state on the map to see the impact of NIH funding across America.

I just reached out to my senators about the NIH situation. If you need to find out how much impact NIH has in your state in terms of dollars in and their economic impact here's a link: www.unitedformedicalresearch.org/nih-in-your-...

22.01.2025 21:34 πŸ‘ 1059 πŸ” 767 πŸ’¬ 46 πŸ“Œ 92

All NIH study sections canceled indefinitely. This will halt science and devastate research budgets in universities.

22.01.2025 20:46 πŸ‘ 12266 πŸ” 4988 πŸ’¬ 586 πŸ“Œ 1166
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Single cell and spatial analysis of immune-hot and immune-cold tumours identifies fibroblast subtypes associated with distinct immunological niches and positive immunotherapy response - Molecular Canc... Cancer-associated Fibroblasts (CAFs) have emerged as critical regulators of anti-tumour immunity, with both beneficial and detrimental properties that remain poorly characterised. To investigate this,...


πŸ””πŸ§ͺInteresting and potentially transformative!

#Immunotherapy uses the immune system to fight #cancer but isn't always #effective. Researchers at the Uni of Southampton studied cancer-associated fibroblasts to understand #treatment #failures.

πŸ‘‡
molecular-cancer.biomedcentral.com/articles/10....

12.01.2025 09:56 πŸ‘ 25 πŸ” 5 πŸ’¬ 2 πŸ“Œ 0

🧡 New link between translation and oxidative phosphorylation in intestinal stem cells!

πŸ§ͺ A new study in @science.org Advances uncovers how the Nascent Polypeptide-Associated Complex (NAC) acts as a critical regulator of metabolism and cell identity in the gut epithelium.
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12.01.2025 11:17 πŸ‘ 7 πŸ” 2 πŸ’¬ 2 πŸ“Œ 0