Anita Luthi

Next-generation multicolor indicators for in vivo imaging of norepinephrine - Nature Methods Improved red and green indicators for norepinephrine and their characterization are reported. These indicators allow detection of norepinephrine release in awake behaving mice in dual-color fiber phot...

The most sensitive green and red #norepinephrine #sensors engineered to date are out in #naturemethods! Deeply grateful to all our funders and contributors who made this work possible. A true team effort. @erc.europa.eu @snsf.ch doi.org/10.1038/s415...

New preprint alert, from a collaboration with @labluthi.bsky.social and Valerio Zerbi lab at Synapsy Center #GenevaUniversity - great collaboration, special thanks to Francesca Barcellini and Georgios Foustoukos for realizing this work !
www.biorxiv.org/content/10.6...

A commentary on reptile sleep, with recommendation from @anitaluthi.bsky.social @labluthi.bsky.social

@labluthi.bsky.social sends Season's Greetings to all, we look forward meeting you for scientific exchange in 2026!

Oxytocin modulates respiratory heart rate variability through a hypothalamus–brainstem–heart neuronal pathway - Nature Neuroscience Buron et al. show that oxytocin enhances heart rate variability linked to breathing during recovery from stress. This calming and cardio-protective effect is produced through a hypothalamus–brainstem ...

Paper alert!
I’m very pleased to announce the publication of my PhD work, which I carried out under the amazing supervision of Clément Menuet at @inmed.bsky.social
!
Link to the paper in @natneuro.nature.com: www.nature.com/articles/s41...

#RespHRV #oxytocin #RSA #brainstem #HRV

Oxytocin modulates respiratory heart rate variability through a hypothalamus–brainstem–heart neuronal pathway - Nature Neuroscience Buron et al. show that oxytocin enhances heart rate variability linked to breathing during recovery from stress. This calming and cardio-protective effect is produced through a hypothalamus–brainstem ...

Oxytocin modulates respiratory heart rate variability through a hypothalamus–brainstem–heart neuronal pathway

@julie.buron.bsky.social @inmed.bsky.social @insermpacacorse.bsky.social D54@incia-neurocampus.bsky.social

www.nature.com/articles/s41...

@labluthi.bsky.social congratulates Lila Banterle for her successful PhD thesis - an excellent defense was followed by excellent festivities! @anitaluthi.bsky.social @fbm-unil.bsky.social

Two new full professorships strengthen neuroscience at UNIL! | Department of Fundamental Neurosciences - DNF, University of Lausanne Two new full professorships strengthen neuroscience at UNIL! We are delighted to announce that two leading researchers from the Department of Fundamental Neurosciences (DNF) of the FBM UNIL - Faculté...

Congratulations to @anitaluthi.bsky.social and @manumameli.bsky.social 🎓👏

www.linkedin.com/posts/depart...

Congrats Laurent, so well-deserved! Thrilled to be working with you in the near future!

Our conclusion: there is a signature of IH in sleep but the causes might be found in wake!

Thanks @institutducerveau.bsky.social, @inserm.fr, @aphp.bsky.social and @erc.europa.eu for supporting this work!

EEG Signature of Idiopathic Hypersomnia: Insights from Sleep Microarchitecture and Hypnodensity Metrics Background and Objectives: Patients with idiopathic hypersomnia with long sleep time (IH) report daytime hypersomnolence despite prolonged sleep time and normal sleep macrostructure. As they often hav...

And here is the preprint:
www.biorxiv.org/content/10.1...

@LabLuthi congratulates Dr. Georgios Foustoukos for the Best Publication Award 2025 from the #SSSSC, the #Swiss Society for #Sleep Research, Sleep Medicine and #Chronobiology. A nice recognition of your outstanding experimental and analytical skills!👏 @fbm-unil.bsky.social @natneuro.nature.com

👉👉new paper alert from @labluthi.bsky.social - so proud for talented and determined Dr.Najma Cherrad who opened the lab‘s access to brain-body communication! #sleep #locuscoeruleus #parasympathetic @fbm-unil.bsky.social

👉👉new paper alert from @labluthi.bsky.social - so proud for talented and determined Dr.Najma Cherrad who opened the lab‘s access to brain-body communication! #sleep #locuscoeruleus #parasympathetic @fbm-unil.bsky.social

Can you learn while sleeping? Does sleep help you solve problems? What is the effect of sleep on brain metabolism?
--> my last editorial @braincomms.bsky.social
doi.org/10.1093/brai...

Sleep is not a homogenous state - just like wake. Asking the role of sleep is as fair as asking the role of wake!

Here's our latest issue: www.cell.com/neuron/current

The cover is for a Perspective piece by Lüthi & Nedergaard who discuss microarousals, and propose an inverted U-shaped relationship to reconcile their essential and disruptive roles: www.cell.com/neuron/fullt...

Cover by Nadia Alzoubi

What a pleasure to be interviewed by science writer @davidarobson.bsky.social, what an even greater pleasure to read his visionary narrative in BBC future!

Agree! Watch out for a first Perspective on this proposed by Maiken and me, coming out on Monday, Jan 13, in Neuron.

@anitaluthi.bsky.social

Important study on the timing pattern of #sleep #spindles in human EEG and of fingerprints that characterize individuals across age and demographic factors 👏👏

Merci Thoma!

Infraslow noradrenergic locus coeruleus activity fluctuations are gatekeepers of the NREM–REM sleep cycle - Nature Neuroscience Lüthi and colleagues show that activity of the locus coeruleus (LC) is crucial for the cyclic alternation between non-rapid-eye-movement and rapid-eye-movement sleep. Stressful experiences during waki...

Amazing work from the team of Anita Lüthi!

Infraslow noradrenergic locus coeruleus activity fluctuations are gatekeepers of the NREM–REM sleep cycle
www.nature.com/articles/s41...
💤🧪🧠

Une nouvelle horloge pour structurer le sommeil Des scientifiques au sein de la FBM-UNIL ont identifié un nouveau rôle du locus cœruleus dans le sommeil et ses troubles. Cette région cérébrale permet la transition entre les états du sommeil et le m...

Alors c’est parti: 1er post, en français:

Récente découverte @unil.bsky.social: une toute petite région du cerveau qui s’appelle « locus coeruleus » détermine si nos nuits sont bien rhythmées entre les phases du #sommeil paradoxal et profond.

www.unil.ch/news/1723726...

Infraslow noradrenergic locus coeruleus activity fluctuations are gatekeepers of the NREM–REM sleep cycle - Nature Neuroscience Lüthi and colleagues show that activity of the locus coeruleus (LC) is crucial for the cyclic alternation between non-rapid-eye-movement and rapid-eye-movement sleep. Stressful experiences during waki...

🔵 blue spot alert: Anita Luethi's team reports a dual role of #locuscoeruleus in #sleep in Nature Neuroscience @natureportfolio.bsky.social

1) high LC activity facilitates cortical microarousals
2) low LC activity is required for NREMS-to-REMS transitions

doi.org/10.1038/s415...