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Jack Holcombe

@jackholcombe

Science, data and climbing http://jackholcombe.com/

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27.09.2023
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Latest posts by Jack Holcombe @jackholcombe

Such a tease!

10.03.2026 13:09 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Netanyahu: β€˜These So-Called Genocide Experts Have Probably Never Committed A Genocide In Their Lives’

Netanyahu: β€˜These So-Called Genocide Experts Have Probably Never Committed A Genocide In Their Lives’

Netanyahu: β€˜These So-Called Genocide Experts Have Probably Never Committed A Genocide In Their Lives’ https://theonion.com/netanyahu-these-so-called-genocide-experts-have-probably-never-committed-a-genocide-in-their-lives/

05.03.2026 22:00 πŸ‘ 2840 πŸ” 594 πŸ’¬ 33 πŸ“Œ 28

Hegseth has admitted that America has *no interest* in "fighting fair." And what it did to that warship near India was an obvious war crime; even the Nazis rescued drowning sailors. So one would have to be naive to say the US-IDF alliance "wouldn't" issue strategic drone strikes.

05.03.2026 16:49 πŸ‘ 622 πŸ” 106 πŸ’¬ 5 πŸ“Œ 3
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Thirty-six solutions to stabilize Earth’s climate An updated visual assessment tool can bridge the gap between climate research and political action

Thirty-six solutions to stabilize Earth’s climate | Science www.science.org/doi/10.1126/... πŸ§ͺ

05.03.2026 22:22 πŸ‘ 44 πŸ” 22 πŸ’¬ 1 πŸ“Œ 0

Congrats!

03.03.2026 08:22 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

My paper on how the fruit fly foregut uses a modified cell cycle to respond to tissue damage and cell loss is now published :)

www.nature.com/articles/s41... #proventriculus #drosophila

03.03.2026 02:48 πŸ‘ 42 πŸ” 11 πŸ’¬ 4 πŸ“Œ 1
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'I didn't grow up wanting to be a politician, I'm a plumber'

The green Party's Hannah Spencer has won the Gorton and Denton, with Reform in second and Labour finished third

27.02.2026 06:55 πŸ‘ 1699 πŸ” 349 πŸ’¬ 72 πŸ“Œ 86

Havent seen the sun in weeks Kevin, allow it this once πŸ˜‚

27.02.2026 09:17 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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First bike to work without a coat this year! (Also whats that weird colour in the sky???)

27.02.2026 09:00 πŸ‘ 3 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

@rorylcooper.bsky.social πŸ‘€?

17.02.2026 14:22 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

πŸ™

03.02.2026 10:03 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Never pee near scope, ends badly

03.02.2026 09:28 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Job alert! πŸ“£ I’m looking for a research assistant to join my new team @idrm.ox.ac.uk

Were using #zebrafish to understand gene-environment interactions that shape the heart πŸ«€generate natural diversity 🐸🐭 and contribute to congenital defects β€οΈβ€πŸ©Ή

Full info below, and please share! 🫢🏻

bit.ly/467TO0M

02.02.2026 14:01 πŸ‘ 34 πŸ” 22 πŸ’¬ 0 πŸ“Œ 1
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Have a look at our latest preprint, "Nuclear plasticity regulates macrophage phagocytic capacity in vivo".

#apoptoticbodies #efferocytosis #nucleus #Drosophila #macrophages #mechanoresponse #InVivo #LiveImaging

doi.org/10.64898/202...

26.01.2026 11:22 πŸ‘ 4 πŸ” 3 πŸ’¬ 2 πŸ“Œ 0

Very cool, congrats!

26.01.2026 13:42 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Amazing city, even better lab!

20.01.2026 19:12 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Congrats! So Beautiful!!

11.12.2025 09:17 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Aaand... my first cover!!

RpS6 phosphorylation (magenta) in a Udd (ribosome biogenesis factor) mutant ovary πŸ”¬

10.12.2025 21:35 πŸ‘ 32 πŸ” 6 πŸ’¬ 5 πŸ“Œ 0
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🚨 Come join us @sheffielduni.bsky.social for a PhD on the evolution and development of feathers and flight! πŸ£πŸ”¬

This project is supervised by @matt-towers.bsky.social & @alexgfletcher.bsky.social, and I'm excited to be involved as a project advisor. Please share!

www.findaphd.com/phds/project... πŸ§ͺ

03.11.2025 14:46 πŸ‘ 36 πŸ” 18 πŸ’¬ 3 πŸ“Œ 1

Lovely to see this, congrats @senapati.bsky.social !

24.10.2025 14:15 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Visceral signaling of post-ingestive malaise directs memory updating in Drosophila Consolidation is a time when labile memories transition to a stable form. Malaise learning in Drosophila reveals consolidation to also permit memory updating. Flies taught to associate one of two odor...

@senapati.bsky.social latest and greatest! Charly Treiber on board too. Over and out.

www.biorxiv.org/content/10.1...

23.10.2025 20:32 πŸ‘ 42 πŸ” 17 πŸ’¬ 1 πŸ“Œ 1
A painting of a very large hog.

A painting of a very large hog.

AWS is down, post hog

20.10.2025 10:05 πŸ‘ 4639 πŸ” 1015 πŸ’¬ 63 πŸ“Œ 83
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These ancient bumblebees were found with their pollen source Insects have long pollinated plants, but evidence of ancient pairing is rare. Fossils now show bees and linden trees goes back 24 million years.

Scientists just found several fossil bumblebees covered in pollen that directly matches fossil flowers nearby.

The 24-million-year-old discovery reveals the oldest known evidence connecting pollinators to the pollinated.

#Paleontology #NationalFossilDay

πŸ§ͺ🏺

New at @sciencenews.bsky.social

15.10.2025 18:22 πŸ‘ 456 πŸ” 112 πŸ’¬ 12 πŸ“Œ 10
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Happy to share the last version of our story @currentbiology.bsky.social on the role of interfacial tension in mechanical cell competition led by @leovalon.bsky.social and Alexis Matamoro Vidal
www.sciencedirect.com/science/arti...

09.10.2025 15:27 πŸ‘ 71 πŸ” 27 πŸ’¬ 3 πŸ“Œ 0
Black and white portrait of John Gurdon, 1971

Black and white portrait of John Gurdon, 1971

John Gurdon, former Group Leader and Head of @cellbiol-mrclmb.bsky.social has died.
Despite calling himself a "total non-intellectual” his work to reprogramme somatic cells to pluripotent stem cells transformed the field of developmental biology.
More: www2.mrc-lmb.cam.ac.uk/john-gurdon-...
#LMBNews

08.10.2025 08:49 πŸ‘ 99 πŸ” 32 πŸ’¬ 3 πŸ“Œ 3

Thankyou so much Helena!

02.10.2025 07:11 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Firm linked to Baroness Michelle Mone must pay Β£122m after breaching Covid PPE contract, judge rules The government wins its case against PPE Medpro - part of a consortium led by Baroness Mone's husband - after it supplied non-compliant gowns in 2020.

Bloody lovely

www.bbc.co.uk/news/live/cy...

01.10.2025 12:26 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Was listening to the bbc coverage of this yesterday and was thinking the same! I need to read the paper itself but would be interesting to see why skin and not some other accessible tissue?

01.10.2025 07:18 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Figure 1: Fluorophore intensity in the Drosophila blastoderm (n.c. 14). Comparison of (A) green and (B) red fluorescence intensity using the same intensity scaling in n.c. 14. The fluorescence signal did
not saturate. Shown are single imaging planes. Normalised histograms of fluorescence intensity for green (C) and red (D) fluorophores averaged across at least n=3 embryos per line. Scale bars = 20 ΞΌm

Figure 1: Fluorophore intensity in the Drosophila blastoderm (n.c. 14). Comparison of (A) green and (B) red fluorescence intensity using the same intensity scaling in n.c. 14. The fluorescence signal did not saturate. Shown are single imaging planes. Normalised histograms of fluorescence intensity for green (C) and red (D) fluorophores averaged across at least n=3 embryos per line. Scale bars = 20 ΞΌm

Identification of optimal fluorophores for use in the Drosophila embryo by Timothy E Saunders and team: www.biorxiv.org/content/10.1...

30.09.2025 14:43 πŸ‘ 54 πŸ” 26 πŸ’¬ 1 πŸ“Œ 0
Developmental Biology and Disability - the Node Hopeful monsters. Morphospace. Mutation. Natural variation. Mutagenesis screens. Polymorphism. Deformity. Phenotype. Disease. Adaptation. Anomaly.

I wrote something on developmental biology and disability and put it up on the node last night:

thenode.biologists.com/developmenta...

I've been nervous to share because some of it veers a bit personal but they are thoughts that won't stay quiet. Would love to know what people think about it!

30.09.2025 09:38 πŸ‘ 39 πŸ” 19 πŸ’¬ 6 πŸ“Œ 3