Andrea Tricco

The epistemological trap from the real-world evidence concept. - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Frontiers | Using an implementation science approach to enhance advance care planning practice: a community case study The process of advance care planning (ACP) can educate and prepare patients and caregivers to make better in-the-moment end of life decisions. Two nationwide...

Check out this recent publication about improving implementation of advance care planning, led by the Geriatric Education & Research Institute in Singapore & co-authored by KT Program Director & Scientist Dr. Sharon Straus:

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bit.ly/4aYYNSZ @andreatricco.bsky.social #ImpSci

The influence of exposure and observed mortality definitions when estimating lung cancer attributable mortality to secondhand smoke exposure - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Ratios are misleading exposure variables that compromise a regression model unless fundamental scaling assumptions are satisfied: a comment on Valente et al - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Use of clustering techniques for clinical and epidemiological research: practical tips using an example from rheumatology - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Drug Approvals in Crowded Drug Classes Potentially Reflect Efficacy Over-Estimates and False Positivity: A Portfolio Analysis of Immune Checkpoint Inhibitor Trials Institutions making decisions regarding drug development, approval or insurance reimbursement require accurate estimates of drug efficacy that reflect the drug’s true value. Stein estimation and multi...

Drug Approvals in Crowded Drug Classes Potentially Reflect Efficacy Over-Estimates and False Positivity: A Portfolio Analysis of Immune Checkpoint Inhibitor Trials - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Influences on recruitment and retention to mental health randomised controlled trials from the perspective of trial staff: a qualitative evidence synthesis. Poor recruitment and retention are widely reported as problematic for many randomised controlled trials (RCTs). However, there is limited evidence on the context specific challenges faced by trial sta...

Influences on recruitment and retention to mental health randomised controlled trials from the perspective of trial staff: a qualitative evidence synthesis. - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Evaluating empirical calibration of P-values under unmeasured confounding bias: a simulation study and real-world application - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Evaluation of GRADE Approach Adherence in Clinical Practice Guidelines: A systematic survey of criteria and their applications Many clinical practice guidelines (CPGs) claim to follow the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach, yet their actual adherence remains uncertain. We aimed...

Evaluation of GRADE Approach Adherence in Clinical Practice Guidelines: A systematic survey of criteria and their applications - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

STrategies for developing REseArch Methods guidance (STREAM): protocol - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Prioritizing topics for a Clinical Practice Guideline on SATB2-Associated Syndrome: Methodological rigor versus clinical usability - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

No Normal Brain: How Demographic Exclusion Undermines Neuroimaging AI Validity - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Estimating effective sample sizes using standard errors from appropriate analyses of cluster-randomised trials - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Psychometric properties and reference values for the instrumented timed-up and go test in adults The instrumented Timed Up and Go (iTUG) test is widely used in assessing mobility and predicting falls. However, the psychometric properties of a smartphone-based iTUG remain unclear, particularly wit...

Psychometric properties and reference values for the instrumented timed-up and go test in adults - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Existing Research Guidelines for Inclusive Trial Methodology. Working toward the integration of Qualitative Research, Equity, diversity, and inclusion (EDI) and Trial Methodology: a focused mapping review. - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Quantifying new threats to health and biomedical literature integrity from rapidly scaled publications and problematic research - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Estimating Causal Effects on Quality of Life Under Treatment Discontinuation: The ALTA-1L Trial - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Crossing the null does not mean “no effect”: a survey of internal medicine physicians on the interpretation of effect estimates with wide confidence intervals - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Rethinking clinical trials in the multimorbidity era: The imperative for patient-centered tailored approaches - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Practical elements to consider when emulating a target trial - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Unity Health Toronto’s February Honour Roll Every month, staff, researchers, physicians, learners and teams across Unity Health Toronto celebrate important honours, achievements and awards. Congratulations to all who’ve been recognized in…

Check out the @unityhealthto.bsky.social Honour Roll for February, featuring KT Program Scientist Dr. Jennifer Watt! 😊

unityhealth.to/2026/02/febr...

@uoftmedicine.bsky.social #GeriSky

Dr. Tricco shares guidance on patient and public engagement in evidence synthesis, grounded in intersectionality and critical reflexive approaches. She also discusses how SPOR EA co-builds patient and community capacity in research and how to incorporate equity in evidence synthesis.

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KT Canada e-Newsletter

KT Canada newsletter for Feb. 25, 2026:

mailchi.mp/886351ad58a8...

#ImpSci #HealthEquity #HealthEcon

@sporalliance.bsky.social @andreatricco.bsky.social

Pls share - upcoming workshop on Advanced Methods for Economic Evaluation: With Health Equity and Person-Level Data

Registration is required but there is no fee.

Download the course PDF for more info, including prerequisites: bit.ly/4kU3GBu

@unityhealthto.bsky.social @andreatricco.bsky.social

Join us for the next session of the KT Canada Seminar Series!

ktcanada.org/event/kt-can...

#ImpSci #MentalHealth #OlderAdults

@andreatricco.bsky.social

Implementation of the Comparison of Outcomes and Access to Care for Heart Failure (COACH) Trial The Comparison of Outcomes and Access to Care for Heart Failure (COACH) trial demonstrated that use of a point-of-care risk assessment tool and a rapi…

KTP scientists Drs. Tina Fahim, Sharon Straus & team also published a manuscript detailing how the COACH trial was implemented across study sites.

Read that article here! bit.ly/3TqEgic

#ImpSci

@andreatricco.bsky.social

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Trial of an Intervention to Improve Acute Heart Failure Outcomes | NEJM Patients with acute heart failure are frequently or systematically hospitalized, often because the risk of adverse events is uncertain and the options for rapid follow-up are inadequate. Whether th...

February is #HeartMonth!

Learn here about the COACH trial, led by Dr. Doug Lee in collaboration with KTP scientists. The COACH trial, published in the @nejm.org, improved outcomes for patients with acute heart failure outcomes.

Read on: bit.ly/3Ut7ezB

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Looking to assess adherence to TRIPOD+AI?

We have a new #openaccess paper in @jclinepi.bsky.social

"Adherence to TRIPOD+AI guideline: an updated reporting assessment tool"

--> linkinghub.elsevier.com/retrieve/pii...

#machinelearning #AI #metascience #transparency

Evaluation of tools used to assess adherence to PRISMA 2020 reveals inconsistent methods and poor tool implementability: part I of a systematic review Numerous studies have assessed the adherence of published systematic reviews to the PRISMA 2020 statement. We aimed to summarize the characteristics and methods of development of the tools used to ass...

#CochraneDaily Just published! Study of assessments of adherence to PRISMA 2020 reveals inconsistent methods and poor tool implementability, highlighting the need for a standardised #PRISMA 2020 assessment tool, which the authors are working on
www.jclinepi.com/article/S089...
@jclinepi.bsky.social

Implementation and Outcomes of a Perioperative Geriatrics Strategy, PRIME, for Older Adults Undergoing Gastrointestinal Cancer Surgery Older adults undergoing gastrointestinal surgery for cancer or pre-cancerous lesions received a whole pathway perioperative geriatrics strategy which included preoperative comprehensive geriatric assessment, collaborative care between surgery, ...

...to sustain its continued impact across clinical settings and better patient outcomes.

Read the full paper, co-authored by KTP scientist Dr @ericwongmd.bsky.social, here!
pmc.ncbi.nlm.nih.gov/articles/PMC...

#WorldCancerDay #GeriatricOncology #ImpSci #GeriSky
@andreatricco.bsky.social

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