thanks for reading

💪🏽 A look into the steroids 💪🏿

HBcore Positive (previously exposure to the virus) but negative HBsAg

Or, if you prefer, by serology
HBsAg + (Chronic hepatitis B)

🩸 For individuals at potential risk of HBVr, AGA recommends testing for hepatitis B (Strong recommendation, moderate certainty evidence)

🌎 Note that CDC recommends hepatitis B screening for all adults aged 18 years and older at least once in their lifetime

⚠️For individuals at moderate risk of HBVr, AGA suggests antiviral prophylaxis over monitoring alone. (Conditional recommendation, moderate certainty evidence)

🕵️‍♀️ For individuals at potential risk of HBVr, AGA recommends testing for hepatitis B (Strong recommendation, moderate certainty evidence)

PPX should be started before these meds and continued for at least 6 mo. after discontinuation of risk-imposing therapy (at least 12 months for B cell–depleting agents) 🚑

🚨For individuals at high risk of HBVr, AGA recommends antiviral prophylaxis over monitoring alone. (Strong recommendation, moderate certainty evidence) 💊

But first, details 🤓
📍Developed using GRADE framework
📍Stratifying of risk of HBVr into low, moderate, or high-risk

AGA Clinical Practice Guideline on the Prevention and Treatment of Hepatitis B Virus Reactivation in At-Risk Individuals Hepatitis B reactivation (HBVr) can occur due to a variety of immune-modulating exposures, including multiple drug classes and disease states. Antiviral prophylaxis can be effective in mitigating the ...

🚨 AGA New Guideline Alert Link🚨
▶️ AGA Clinical Practice Guideline on the Prevention and Treatment of Hepatitis B Virus Reactivation in At-Risk Individuals
I’ll break down its FIVE recommendations over the next 12 posts 🧵 👇
#AGA #GI #HBV

www.gastrojournal.org/article/S001...