Régis Joulia

Starting Monday! Last chance to sign up for this highly rated beginner #bioinformatics course and gain practical omics analysis skills 🚀

Book your place here: bit.ly/46C2QDC

Epidermal growth factor receptor controls sex differences in lung type 2 responses to inhaled allergen Female mice have exacerbated, EGFR-dependent lung type 2 immunity when exposed to inhaled house dust mite throughout sexual maturation.

Hello world, it's a g̶i̶r̶l̶/̶b̶o̶y̶ PhD baby 🎉

Very elated, proud (and relieved!) to announce that my PhD work is now out in @science.org #ScienceImmunology 👇 www.science.org/doi/10.1126/...

Read to find out how we made EGFR sexy again! 💃

Thanks to all involved @lloydlab.bsky.social 🙏

It was an absolute pleasure to hear Ron Germain speak at Imperial College yesterday. His seminar was a brilliant deep dive into immunology and cutting-edge imaging approaches. A real highlight was the chance to discuss science with him afterwards with Peter Openshaw and Cecilia Johansson !

I’m so excited to share that my paper on the role of itaconate in allergic airway disease and asthma has just been published in @allergy-eaaci.bsky.social!

You can read the paper here: onlinelibrary.wiley.com/doi/10.1111/...

#itaconate #allergy #asthma #immunometabolism #innateimmunity

Research Associate | King's College London

We are recruiting!!! Postdoc position available in my lab to develop this exciting project with @alexfsantos2401.bsky.social advance our understanding of food allergy and oral tolerance in early life. #ILC #organoids #FoodAllergy

www.kcl.ac.uk/jobs/128585-...

We hiring! Please share this post with your talented ECRs

We're looking for a postdoc interested in the formation and function of tertiary lymphoid structures - project funded by Wellcome

Based at @lmcb-ucl.bsky.social at University College London

Apply here:
www.jobs.ac.uk/job/DPD418/r...

Barrier sites under the microscope! 🔬

Discover how our skin, gut & lungs fight infection, heal, and keep our microbiota happy. Don’t miss this session at #BSI25!

PS. Early bird registration closes on Wednesday 22 October ⚡

Don’t waste your time with formatting changes, submit your format free manuscript to MI and support society-sponsored journals.

🌟 It was a real pleasure to present our latest spatial data yesterday at the @10xgenomics.bsky.social Single Cell & Spatial Event !

An inspiring day with exciting innovations from 10x, great discussions, and an incredible venue. 🚀

@imperialnhli.bsky.social @imperialmed.bsky.social

Applications for the Crick PhD programme now open. One studentship available in our lab, starting Autumn 2026. Apply!

Description Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...

🚨 We are #recruiting! 🚨My lab is looking for a highly motivated Research Technician to join us for the next 3 years.

👉 Apply via the link www.imperial.ac.uk/jobs/search-... or feel free to reach out for more information!

Epithelial cell-derived lumican modulates extracellular matrix dynamics in early-life airways disease

New paper alert - congratulations, Franz & team 🥳

Epithelial cell-derived lumican modulates extracellular matrix dynamics in early-life airways disease - Journal of Allergy and Clinical Immunology www.jacionline.org/article/S009...

For our #flowcytometry peeps, would you like to have a single fix/perm protocol that is optimised for everything? One that preserves fluorophores while allowing simultaneous TF and cytokine staining? How about 100-fold cheaper?

You got it:
currentprotocols.onlinelibrary.wiley.com/doi/10.1002/...

Picture of Régis Joulia and text reads: Cambridge Immunology Forum 2025, Dr Régis Joulia, Imperial College London, UK, How mast cells orchestrate and disrupt specialised immune niches in the lungs and beyond, #BSICambridge25, Join us on 23 September. Also includes logo of British Society for Immunology and Cambridge Immunology Network.

📢 Meet #BSICambridge25 speaker: @regisjoulia.bsky.social

Dr Régis Joulia, @wellcometrust.bsky.social -funded Group Leader @imperialnhli.bsky.social, will be speaking on mast cells in the lungs at the 2025 Cambridge Immunology Forum.

🎟️ Register now: buff.ly/jhoEQJ0

@britsocimm.bsky.social

What is happening at the lung wall during immune response and what goes wrong in asthma? YouTube video by Imperial NHLI

NHLI's Joulia Lab made a short animation explaining what goes wrong in the lungs during asthma! 🫁📽️

Check out how immune cells respond to threats & how asthma treatments work. With thanks to
Wellcome Trust & Acteria

Watch it here: youtu.be/Skp_CNWOYSA

We made a short animation explaining what goes wrong in the lungs during asthma! 🫁🎬 Designed for the public, students & patients—check out how immune cells respond to threats & how asthma treatments work.

Big thanks to @WellcomeTrust & Acteria!

🎉 Exciting news! I’ve recently been elected to the @britsocimm.bsky.social Congress Committee and to the Board of the @societymucosalimm.bsky.social (SMI) representing the voices of ECRs! Looking forward to working with these fantastic scientific organisations.

www.immunology.org/news/new-bsi...

Frontiers | Walking on the tightrope: the shared roles of the bridging pericytes in the brain The vasculature of the central nervous system (CNS) is a highly specialized structure that delivers oxygen and nutrients to energy-demanding neural cells whi...

🚨 Review Alert

*Walking on the tightrope: the shared roles of the bridging pericytes in the brain*

Congratulations Audrey Chagnot!! 🥳

Bias aside, this feels like a really meaningful piece for the cerebrovascular field! 😊

www.frontiersin.org/journals/cel...

1/ 🚨 Hot off the press in Nature Immunology: CD4⁺ T cells can license Kupffer cells to rescue dysfunctional CD8⁺ T cells in the liver. Hepatitis B virus (HBV) infection is just the proving ground—this is a paradigm shift in tissue immunity. www.nature.com/articles/s41... 🧵(1/11)

Research Associate in Mucosal Immunology :Manchester

🚨 The Menon lab is hiring a postdoc!

Interested in mucosal immunology? Come join our team to study lung-infiltrating B cell dynamics in COPD & other chronic lung diseases
@ukri.org @lydiabeckeriii.bsky.social

Please help spread the word #ImmunoSky

www.jobs.manchester.ac.uk/Job/JobDetai...

#Immunologists - have you signed up for BSI's @london-immuno.bsky.social 1d conference yet?
Fri 11th July

Speakers include: Jan Böttcher, Tao Dong, @labliston.bsky.social, @beecell.bsky.social, Claudia Mauri & Claire Malone

REPOST to share as widely as poss

www.immunology.org/events/diver...

#EVBOSeminarSeries Moderated by Joanna Kalucka. Speakers: Ralf Adams and Mariona Graupera. ⏰When: Wednesday, 18th June 2025, 3PM EU time (2PM UK). Place: online. See you there! For registration evbo.org

A single-cell spatial chart of the airway wall reveals proinflammatory cellular ecosystems and their interactions in health and asthma Nature Immunology - Here, the authors use single-cell spatial transcriptomics to profile the airway wall landscape in health and during asthma. Discrete proinflammatory ecosystems containing...

Joulia et al use single cell spatial transcriptomics to profile the lung in health and during asthma and identify discrete proinflammatory spatial niches that produce alarmins and chemokines. Read it here: rdcu.be/epjN7
www.nature.com/articles/s41...

Nociceptor neurons suppress alveolar macrophage-induced Siglec-F+ neutrophil-mediated inflammation to protect against pulmonary fibrosis Sensory innervation impacts several lung diseases, but whether it influences pulmonary fibrosis (PF) is unclear. Hiroki et al. report that depletion of TRPV1+ nociceptors leads to worsening of inflamm...

Our latest work on how nerves safeguard lung fibrosis. Congrats to Dr. Hiroki and collaborators. @cp-immunity.bsky.social @kavithascranton.bsky.social @hotchkissbrain.bsky.social @ucalgary.bsky.social @ucalgarymed.bsky.social @libininstitute.bsky.social

www.cell.com/immunity/abs...

Location matters: defining the architecture of the bronchial wall in health and asthma - Nature Immunology Using spatial single-cell transcriptomics of human lung biopsies, we mapped cellular interactions at the airway wall in health and asthma. We identified specialized cellular communities marked by high...

Our recent Nature Immunology paper is featured in the latest Nature Research Briefing, offering more context and our perspective on the findings and the power of spatial transcriptomics.

www.nature.com/articles/s41...

Pioneering spatial map of the airways could transform understanding of asthma | Imperial News | Imperial College London Researchers have identified distinct differences in the spatial organisation of cells in the airway of healthy people and those with asthma.

Our researchers have created the first high-res map of the lung airway wall, revealing how cell organisation & interactions are disrupted in asthma 🫁

Published in @natimmunol.nature.com, it's a key step towards understanding the mechanisms that drive the disease

www.imperial.ac.uk/news/264294/...

MRC MultiSci iCASE Studentships MRC MultiSci iCASE Studentships enable graduates with excellent honours degrees to undertake a three and a half year training programme, which includ...

We have a funded PhD studentship on RSV antibodies working with RQ bio, deadline June 30

www.imperial.ac.uk/medicine/stu...

#SpatialBiology #Asthma #MastCells #Transcriptomics #LungImmunology #ImperialCollegeLondon

@britsocimm.bsky.social @natrevimmunol.nature.com @imperialnhli.bsky.social @10xgenomics.bsky.social @brukerspatial.bsky.social @nature.com @societymucosalimm.bsky.social @asthmaandlung.org.uk

👉 What’s next? We’re diving deeper into the makeup and function of these ecosystems, exploring how treatments—and other lung diseases—reshape them.

Huge thanks to our funders @wellcometrust.bsky.social , @BHF CRE, @ACTERIA and @BRCimperial

🧪 How’s this regulated? Mast cells play a starring role—expressing proteases, amphiregulin, and more. We also found a unique endothelial cell subpopulation expressing ACKR1, which may help retain chemokines locally and structure these immune hubs.