Viewpoint: a critique of pulmonary vascular resistance to define severe pulmonary hypertension ExtractIt has long been known that pulmonary hypertension (PH) associated with lung diseases and/or hypoxia may have a negative impact on functional state, exercise capacity, quality of life and survival [1]. While available data suggest a continuum of disease state with outcome, there has been a consensus among experts that a heart failure or “vascular” phenotype may predominate over background lung disease symptomatology, function and prognosis when PH is “severe” [1]. However, the definition of “severe PH” has evolved over time. In the 2015 European Society of Cardiology (ESC)/European Respiratory Society (ERS) guidelines, “severe PH” was defined by a mean pulmonary artery pressure (mPAP) >35 mmHg, or by an mPAP ≥25 mmHg with a cardiac index <2.5 L·min−1 [2, 3].

Viewpoint: a critique of pulmonary vascular resistance to define severe pulmonary hypertension publications.ersnet.org/content/erj/...

Cellular Communication Network Protein 2 in the Right Ventricle of Pulmonary Arterial Hypertension Cellular communication network 2 (CCN2) is a secreted matricellular protein associated with pulmonary arterial hypertension (PAH) but has not been studied relative to PAH severity, outcomes, or right...

🗞️New research article has just been published in Pulmonary Circulation, exploring ‘Cellular Communication Network Protein 2 in the Right Ventricle of Pulmonary Arterial Hypertension’, authored by Carly E. Byrd Et al. Read the full article onlinelibrary.wiley.com/doi/full/10....

🚨 Last call! Abstract submission for #AHA25 closes today: Thursday, June 5 at 7PM EDT! Join us in New Orleans this November for the premier event in cardiovascular science. Present your work, connect with leaders, and be part of the discovery. @americanheart.bsky.social @sashaprisco.bsky.social

#Pulmonaryhypertension can affect anyone, regardless of their age, gender, race or background.

PH can also be caused by a variety of associated conditions including #schistosomiasis, #CHD, #lupus and #sarcoidosis.

Learn more: buff.ly/VypM6yN

AAMC Statement on Drastic Cuts to NIH-Funded Research Drastic cuts to NIH-funded research will diminish the nation’s research capacity, slow scientific progress, and deprive patients, families, and communities.

“Every American has benefited from NIH-supported medical research conducted at medical schools, academic health systems, and teaching hospitals nationwide. Every American will be harmed by the undermining (@NIH).” www.aamc.org/news/press-r...

Indirect costs from the NIH to be capped at 15%! grants.nih.gov/grants/guide...