Ayse Akcan-Arikan

gravity is doing a better job opposing the GOP than the Democrats are

Any company that "pulls back" on DEI is openly endorsing white supremacy. These are white power people, white power companies.

My #pedsICU friend @akcanarikan.bsky.social is giving the @dgsomucla.bsky.social Pediatric Grand Rounds this Friday

Estimated potassium intake and the progression of chronic kidney disease AbstractBackground and hypothesis. Lower potassium intake is associated with a higher risk of chronic kidney disease (CKD) in the general population. Howev

Most kidney disease patients are still advised the OPPOSITE.
Important to know:
Low potassium intake is associated with worse CKD progression.

academic.oup.com/ndt/advance-...

Machine Learning-Based Prediction Model for ICU Mortality... : Critical Care Explorations ed to predict survival to ICUs and hospital discharge in children and young adults receiving CRRT using machine learning (ML) techniques. DERIVATION COHORT: Patients less than 25 years of age recei...

journals.lww.com/ccejournal/f...

Snow White’s tale in nephrology: the emerging threat of skin-whitening creams on kidney health ABSTRACT. The timeless tale of Snow White, with its emphasis on fair skin as a beauty ideal, mirrors a contemporary issue in nephrology: the harmful impact

Snow White’s tale in nephrology: the emerging threat of skin-whitening creams on kidney health

doi.org/10.1093/ckj/...

www.cambridge.org/core/journal...

Fluid Overload Modifies Hemodynamic Impact of CRRT:... : Shock ence similar cardiovascular effects. Methods Observational single-center study on children (<18 years) receiving CRRT at Texas Children’s Hospital from 11/2019 to 3/2021. Excluded were those with e...

journals.lww.com/shockjournal...

Machine Learning-Based Prediction Model for ICU Mortality... : Critical Care Explorations ed to predict survival to ICUs and hospital discharge in children and young adults receiving CRRT using machine learning (ML) techniques. DERIVATION COHORT: Patients less than 25 years of age recei...

journals.lww.com/ccejournal/f...

Iron Deficiency in the PICU: An Invisible Illness?* : Pediatric Critical Care Medicine An abstract is unavailable.

Iron Deficiency in the #PedsICU An Invisible Illness?

Great Editorial to our paper

@pccmdoc.bsky.social @aabbupdates.bsky.social @natapbm.bsky.social @sccmcriticalcare.bsky.social @jennamillermd.bsky.social @ironmatters.bsky.social @shematologist.bsky.social
#iron

journals.lww.com/pccmjournal/...

The glomerular circadian clock temporally regulates basement membrane dynamics and the podocyte glucocorticoid response

doi.org/10.1016/j.kint.2024.10.016

#OpenAccess #glucocorticoids #podocytes #kidneydisease #circadianrhythm #NephSky #SkyNeph #MedSky

Russia 🤦🏻‍♂️
TOPCAT funny business
evidence.nejm.org/doi/full/10....

Support Us - Sesame Workshop Individual donors and partners can have a major impact. Join Sesame Workshop’s Mission to Help Kids Everywhere Grow Smarter, Stronger, and Kinder.

HBO has declined to renew “Sesame Street” for new episodes. The series that’s been teaching generations of little kids since 1969 now has no studio.

Please consider donating to Sesame Workshop to ensure the residents of 123 Sesame Street are still around to teach kids of all needs and backgrounds.

Modelling human brain development and disease with organoids Nature Reviews Molecular Cell Biology - This Roadmap article discusses recent advances in the production and use of brain organoids to understand brain development and associated disorders. The...

So excited to share our new @natureportfolio.bsky.social review on modeling human brain development using organoids! 🧠 Loved collaborating with the brilliant @lancasterlab.bsky.social , led by the incredible @marcellabirtele.bsky.social Check it out! 🔬 #Neuroscience #BrainOrganoids rdcu.be/d3llp

A fluorescently stained kidney organoid made from stem cells. It shows cells and nuclei that are the precursors of potassium reabsorbing cells in the adult nephron.

Happy holidays! A very cool looking kidney organoid, courtesy of senior Ph.D. student MaryAnne Achieng in the @lindstromlab.bsky.social.

@akcanarikan.bsky.social Interesting article #PedsICU

Ethylene glycol intoxication presents w/ anion gap metabolic acidosis & acute oxalate tubulopathy. Detection of urinary calcium oxalate monohydrate crystals helps in diagnosis [not classic dumbbell nor envelope shaped (dihydrate) but rather “cigar” shaped]. Slide courtesy of @jrseltzer.bsky.social

Effect of protein supplementation on plasma sodium levels in the syndrome of inappropriate antidiuresis: a monocentric, open-label, proof-of-concept study-the TREASURE study - PubMed Our findings suggest that protein powder increases plasma sodium levels in patients with chronic SIAD through protein-induced ureagenesis and osmotic diuresis. The effects are comparable with oral ure...

these investigators found whey protein to be equivalent to urea for SIADH

pubmed.ncbi.nlm.nih.gov/37540987/

that time I called nephrology about one of their acute renal failure patients acting altered and he asked "is he still taking Gabapentin?" and I said "f*ck"

What I look forward to most each year about @hcwvshunger.bsky.social are the blood thirsty rivalries and secret machinations like some kind of Machiavellian plot. Oh that and all the money that gets raised to fight hunger, that’s nice too. 😂

Tizanidine, Benadryl, gabapentin, mirtazapine, baclofen, yadda yadda yadda... polypharmacy.

the number of times polypharmacy goes unrecognized as a cause of “altered mental status” is astounding

A reminder that the improvements that we’ve seen in life expectancy over the centuries are largely driven by preventing infants and children from dying. If you survived past childhood, you probably were going to live to 60.

#PedsICU peeps - spread the word! Return of in-person Peds #SCCMCurrentConcepts this year at the #SCCM 2025 Annual Congress! Register at my.sccm.org

Potassium Rollercoaster Heartbreak — NephJC This week, we will discuss the use of 3K dialysis bath with sodium zirconium cyclosilicate versus 2K bath and no potassium lowering medications in dialysis patients and the associated risk of arrhythm...

Is adding SZC + 3K bath the solution to sudden death in dialysis?

Join us this on #NephJC to discuss

www.nephjc.com/news/potassi...

#NephSky

When insulin was first patented in 1923, the discoverers declined to put their names on it as they felt that insulin belonged to the public.

101 years later, insulin is inaccessible to thousands of Americans because of price gouging by near-monopoly private insurance corporations and their PBMs.

Vancomycin-Associated Acute Kidney Injury with a Steep Rise in Serum Creatinine Abstract. Background: Vancomycin-associated (VA) acute kidney injury (AKI) is being increasingly recognized. A distinct pattern of rapid rise in serum creatinine (sCr) during VA-AKI has occasionally b...

karger.com/nef/article-...

Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections | NEJM Bloodstream infections are associated with substantial morbidity and mortality. Early, appropriate antibiotic therapy is important, but the duration of treatment is uncertain. In a multicenter, non...

🚨 Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections

BALANCE trial publication is here !

#IDsky #Medsky

@idjclub.bsky.social

www.nejm.org/doi/full/10....