Daenerys Targaryen

malcompetence?

If you’re associated with a child trafficker, I don’t give a shit about your profession or political leanings. You deserve to be named, shamed and brought to justice. Period.

Would love a picture update rather than a video so I can zoom in to my area

100%

Please don’t throw them away! I am happy to take them off your hands and make electronic “forever” copies. This is gold!!

The NIH has lost its scientific integrity. So we left “We can no longer lend our credibility to an organization that has lost its integrity,” write four scientists and administrators who recently resigned from the NIH.

www.statnews.com/2026/01/10/n...

Most lanes don’t work and they are just ushering people through. Just builds up a bottleneck. Hope they get the machines working smoothly soon.

The transcription of a single olfactory receptor per neuron is enforced by epigenetic silencing of their enhancers The ability to discriminate thousands of odors in our environment requires each olfactory neuron to express a single olfactory receptor from hundreds of available genes. The biochemical mechanism enfo...

This went under the radar but answers a fundamental question in Epigenetics...

From many hundreds of olfactory receptor genes, each neuron selects expression of only single one (near-randomly). How?

Outstanding work from Mathieu Boulard and colleagues

www.biorxiv.org/content/10.6...

Today is a big day.

After many years of work, I’m excited to finally share a paper describing a novel approach to identifying potential breakthroughs in biomedical research, up to twelve years before the breakthrough itself occurs. 1/15

AS A PROFESSOR, I AM ASKING

HOW ARE OUR STUDENTS SUPPOSED TO LEARN IN THESE CONDITIONS?

HOW ARE THEY SUPPOSED TO GO TO SCHOOL AND TAKE EXAMS KNOWING SOMEONE MIGHT JUST SHOW UP WITH AN EASY TO ACQUIRE AUTOMATIC WEAPON?

HOW??????????

BRCA1 turned 30 🎉
To celebrate, Jos Jonkers and I explored three decades of BRCA1 research - what we’ve learned about its biology, its role in tumorigenesis and future directions to improve the life of BRCA1 mutation carriers.
Now out in Cancer Discovery ⬇️: aacrjournals.org/cancerdiscov...

AOC: I don’t celebrate RAPISTS, so no, I’m not going to the inauguration tomorrow

If we try to do that in 2000 words with 5 figures, sure, that is what would likely happen. My point is that current publishing media and formats were designed for a type of science that is not the only kind that exists today.

What Can US Cities and States Do for the Climate Under Trump? Plenty Federal progress on climate may stall, but city halls and statehouses are in a good position to build on recent gains.

After Trump was elected, I started to wonder what could the grassroots, cities, and states do to move the needle on climate change without federal support. It turns out, a lot (gift link)

Besides evidence of heterogeneity, are there instances of single cell functional genomics being used in a therapeutic space? Could you please point to literature?

RNA editing is a molecular clock in unmodified human cells Despite major advances in spatial RNA sequencing, the ability to extract temporal information in RNA sequencing experiments is still limited. Here, we describe Transcriptome Timestamping (T2), a syste...

www.biorxiv.org/content/10.1...

A gentle introduction to pangenomics https://academic.oup.com/bib/article/25/6/bbae588/7902219

Pinning this for myself: I am determined to be kinder, gentler on this site compared to the netherworld we left - more like how we behave in the real world. Will still have a lot of (ideally constructively) critical things to say & have plenty of arguments especially on controversial topics. But 1/

Does biotech prepare you for the presidency? Who really wants to gut the FDA? And why do drug companies struggle with IT?

www.statnews.com/2023/08/24/p...

From left to right
CSO CEO CFO #biotech