Cool molecule pictures online

An unwarrantedly smug face drawn in sharpie on a red balloon connected to a flask with a needle.

Forgot to share my hydrogenation balloon from the other day!

Tragically his smug demeanor did ~not~ enhance the hydrogenation yield.

Scientists really out here building death receptor armored cars

When does the bubble pop? It's lasted years longer than I expected. Glad I never tried shorting

Got a temp ban on Twitter for telling a n*zi to **** ********

Isn't that ~1$ per sample? Or does your group use significantly more D2O than organic chemists?

Epoxide and Michael acceptor 🫣
en.wikipedia.org/wiki/Trichot...

the structure of vomitoxin, which is a reasonably complex bicyclic structure

TIL vomitoxin

en.wikipedia.org/wiki/Vomitoxin

Today I got data that shows the compound won't even work. I love creating polution

I need 4 drops of a ragent but the smallest bottle is 50 mL

Shifting Gears: Photochromic Metal–Organic Frameworks with Stimulus-Adaptable Performance The tunability of the reaction parameter space is probed in the presented work through photoswitch-directed energy and charge transfer pathways induced by organic chromophores, hierarchically organized within a well-defined, light-harvesting metal–organic framework. Unique matrix-imposed changes in photoswitch photophysical properties, including the first report of visible light-induced photoisomerization of a spiropyran derivative, illustrate the critical synergy between the selected matrix and the photoresponsive compound. Moreover, the confined space of the utilized porous matrix allowed for mimicking isomerization kinetics of integrated sterically demanding photochromic moieties in solution. More importantly, such photoisomerization suppresses the charge transfer processes in favor of resonance energy transfer pathways instead. The demonstrated ability to shift between multiple relaxation pathways (e.g., charge transfer, energy transfer, or photoluminescence) as a function of the excitation wavelength resulted in photoswitch-directed tailoring of model phosphinylation reaction outcomes. Thus, incorporating spiropyran moieties within the framework allows for visible light to be harvested and funneled toward either a ligand-based reactive center or an acceptor molecule such as a photochromic unit. Moreover, the framework’s chemical activity was promoted exclusively by organic linkers without the participation of metal nodes, the addition of (co)catalysts, or the use of harsh conditions at room temperature. Overall, this work paves the way for the development of stimulus-responsive platforms, for which chemical activity could be controlled through a photochromic moiety.

TOC goes so hard
doi.org/10.1021/jacs...

Idk, have you played Golf With Your Friends? 15 bucks on Steam

www.reddit.com/r/labrats/co...

(new patents are released every Thursday unless they are on vacation)

World Intellectual Property Organization - Wikipedia

en.wikipedia.org/wiki/World_I...

One thing they don't tell you about medicinal chemistry is that you'll have a calendar of holidays in Geneva Switzerland

No citation?? Lol

A "cross-decoupling" or "retro-Suzuki" sequence

Fans of Guenther Schlonk will enjoy the "cross-decoupling" easter egg:

jabde.com/wp-content/u...

Love it when chemical companies sell major and minor tautomers at different prices. I feel like I've found an arbitrage opportunity

Thanks Kimberly

www.nytimes.com/2025/05/27/w...

Are you really a synthetic chemist if you aren't watching USCSB videos?

"The reaction was stirred for 4 days"
-Europeans

We collected the used silica from three months of columns and made an art installation with it. (reddit)
www.reddit.com/r/chemistry/...

"hey we have this inhibitor available"
"hey, do you like the chemical you bought last week? Want to buy another"
These emails are non-stop this week

I got a new recession indicator:
Chemical companies started cold emailing me about compounds I can buy

Thiosulfate forms an S8 impurity that's difficult to detect and will screw over your future cross couplings