Brain Repair Group

We’re looking for a new Research Engagement Manager! This role will ensure that the experience and perspective of people with Parkinson’s are embedded across our research activities. The application deadline is 11:30pm on Tuesday 21 October. Learn more: buff.ly/hcjXMtb

Check out our latest paper: PET and MR imaging of human stem cell derived dopamine grafts. Relationship between PET and different types of behaviour, evidence of glial remodeling in distal areas, and more!

shorturl.at/j9z4r

Join us online on World Parkinson's Day (Friday) to hear from leading scientists in informative sessions & panel discussions🧠🙌

Dr Dayne Beccano-Kelly, Dr @riahlelos.bsky.social & Prof Caleb Webber share their latest research into Parkinson's.

⏰ 11:15 - 15:15 on Friday 11 April 👉 buff.ly/5wlA3dx

www.thebrainrepairgroup.com. Check out our new website! Designed and made by a very talented PhD student in the lab, Phoebe Linehan

👋 Greetings from the Brain Repair Group in Cardiff, UK 👋

Epigenetic memory of Lateral Ganglionic Eminence derived hiPSCs cannot overcome barriers in authentic MSN differentiation Induced pluripotent stem cells (iPSCs) have previously been shown to retain some of the epigenetic features associated with the tissues from which they were derived, which in turn can help the iPSCs t...

For all those stem cells biologists differentiating hPSCs to neurons, want to know how the epigenetic memory of the donor tissue affects subsequent differentiation? We explore this in our recent paper 👇
shorturl.at/m23WC

Cell therapies are in clinical trial for Parkinson's disease, epilepsy and other CNS indications. Here we show that glucose deprivation causes rapid cell death, more so than oxygen deprivation. Improving access to glucose in grafts could improve graft survival

pubmed.ncbi.nlm.nih.gov/39788838/