Sirion Danglaoun

H.pylori nice shot!📸

Could it be astroblastoma???

A sausage shaped tumor with attached filamentous band

A squash preparation of a fibrillary neoplasm with myxoid background

Small rosettes in a squash preparation

H&E stained section of papillae with myxoid cores

Myxopapillary ependymoma grossly has a characteristic sausage-shaped appearance. Commonly found associated with the filum terminale, it has a fibrillary glial appearance in a myxoid background. Though previously categorized as CNS WHO grade 1, it is now considered grade 2 #pathsky #medsky #neuropath

Image of the Week!

Submitted by: Chhanda Das, M.D., D.N.B.
Directory Profile: buff.ly/b7mDAWt
Subspecialty: Neuropathology
Diagnosis: Pituitary adenoma

#Pathology #PathologyOutlines #NeuroPath #PathSky

A 19-year-old man presented with brain tumor at pineal region and cerebellar region.
AE1/AE3 : weak staining
GFAP: focal near 50%
High Ki-67 proliferative index=60%
What is it?
#neuropath #pathology #pathsky #histology #CNStumor #CNSpath

Patient's does not look sick. No cancer identified in patient. No fever. Only anemia. Now, we investigated for cause of this presentation. If there are no evidence, it may be MDS cause.

High grade serous carcinoma in lymphatic vessel at serosa of uterus
#gynpath #pathology #histology #gynepath #serouscarcinoma #uterus #ovary

Spice the cat, going full nap.

For those of you traumatized by the previous post, a cat picture.

Alport syndrome in middle aged man with hx of hearing impair. Presents with proteinuria, RBC 3-5, UPCR 4, SCr 2.5. Characteristic interstitial foam cells noted. #renalpath #pathsky #nephrology

Honeycomb lung 🫁

#pathology
#pathsky

@drdeadright.bsky.social
@sthanu25.bsky.social
@gbosslet.bsky.social
@kerrijohannson.bsky.social

#slidearchiveseries history of radical orchiectomy with pure teratoma, serum tumor markers (post-orchiectomy): AFP 537, increased to 469, HCG 2; status post chemotherapy x 4 cycles ➡️ retroperitoneal lymph node dissection #gupath #pathsky

One of the nastiest skin tumours. This one in a vessel enroute to destroy the respiratory membrane diffusion gradient.
#MerkelCellCarcinoma
#pathology
#dermatology
#PathSky
👿

#PathSky 79M with a superficial neck mass. Wildly pleomorphic, quite cellular- undifferentiated pleomorphic sarcoma, right? There are basically no mitoses though, the cells have abundant granular-glassy cytoplasm, there is a lot of inflammation, and many bizarre cells have nuclear inclusions.

A cute finding in apocrine metaplasia, do you know what it is? #breastpath #pathsky #pathtwitter #pathx #patologia

TFE3

#PathSky 43F with a solitary lung mass. Relatively circumscribed, nests and interesting micropapillae of lightly eosinophilic epithelioid cells. Negative for everything except TFE3. Dx?

Schaumann body - calcified inclusion in a giant cell from a colonic biopsy, Crohn’s patient #pathsky #pathology #GIPathology #histology #histopathology

Patient presented with chronic anemia
Bone marrow biopsy was performed.
+PAS
+CD68
#pathsky #skypath #hemepath #pathology #hemato

3. Disseminated histoplasmosis

If you can spare a moment, please add a teaching point about this infection in the comments @germhuntermd.bsky.social

#pathology #pulmpath #pathsky #pathbugs #crittersonbluesky

Adrenal necrosis
GMS and PAS stains show small uniform oval, narrow based budding yeasts.
Dx. Adrenal histoplasmosis #adrenalgland #histology #pathsky #histoplasmosis #skypath #pathology #idpath

The wording of this diagnosis caught my eye in an old ppt. 32M h/o abd pain and diarrhea after ending steroid therapy for lupus. Histology shows suppurative inflammation limited to the submucosal layer. Phlegmonous enteritis is the given dx, though that seems to be an outdated term. #gipath #pathsky

Vascular invasion #pathsky #histology #melanoma #dermpath

Metastatic malignant melanoma at groin node #pathsky#pathology #histology #melanoma #dermpath

CD117+, CD4+, CD7+, CD68+, EBV-, CD2-, CD5-, ALK-, CD8-, CD56-
Suspicious myeloid sarcoma

The differential diagnosis includes DLBCL+/- EBV, ALCL peripheral T cell lymphoma, histiocytic sarcoma, myeloid sarcoma and mastocytosis. 🙉🙈

Thank you. 🥰😊

To narrow down the differential, I'd guess: CD4, CD8, CD163, ALK, and EBV.

What is the cause of this washed out understaining artifact? It appears randomly and affects only a few biopsies in the batch. #histologyprotocols #medicine #science #pathology #histology #research #histotechnologists #histologysupervisors

Waiting for ALK-1. Sadly, my lab does not have TCR gamma/delta rearrangement. If it turns to T cell lymphoma, I will send it to outside lab. Thank you.😊😀😃

Cute little asteroid body #pathsky #pathology #histology #histopathology