Enfu Hui

Postdoctoral Position in Immunology Post a job in 3min, or find thousands of job offers like this one at jobRxiv!

We are hiring! Several projects available in mucosal immunology and stem cell transplantation using functional genomics and spatial transcriptomics. Could you please help us spread the word? @ljiresearch.bsky.social

Thank you Tim for your kind words!!

For all those providing reviews of scientific papers–firstly, thank you. We would not have a useful scientific literature without you. Secondly, please keep in mind that your reviews are read not only by the PIs but also students. There is no place for anger or impolite language in a review.... 1/

Good night Blue Sky

When did the taste of the scientific community changed from liking simple elegant experiments to preferring complicated and expensive experiments?

📣 DEADLINE COMING UP (Jan 15!) to apply for a short talk at the all-new Keystone Symposium on female reproductive biology!!

The meeting is April 10-12 2025, mark your calendars!
keysym.us/KSFemaleRege...

🧪
@keystonesymposia.bsky.social
#reprosky

A ganglioside-based immune checkpoint enables senescent cells to evade immunosurveillance during aging - Nature Aging This study identifies a novel immune checkpoint in senescent cells that is linked to the ganglioside GD3 and that contributes to the evasion of immune clearance by these cells and to aging and age-rel...

I am thrilled to share that my PhD research project has just been published in @natureportfolio.bsky.social #NatureAging !
We discovered how senescent cells use the ganglioside GD3 as a Senescence Immune Checkpoint to escape immune clearance. #NKcells #Siglec7
www.nature.com/articles/s43...

Thrilled to share I’ll officially start next Monday as a tenure-track Assistant Professor at the Department of Industrial and Molecular Pharmaceutics, Purdue University! My lab will focus on high-precision in vivo biomedical imaging for drug discovery.

Thanks Miguel!

Biochemical and biophysical mechanisms macrophages use to tune phagocytic appetite Summary: Macrophages regulate their phagocytic appetite to rapidly clear pathogens and debris while minimizing damage to the surrounding tissue. We discuss the molecular toolkit for tuning macrophage ...

Macrophages need to adjust their appetite based on whats happening around them... but how to make a macrophage hungrier? Annalise Bond assembled a list of biophysical and biochemical parameters that can tune phagocytosis. @jcellsci.bsky.social @biologists.bsky.social

doi.org/10.1242/jcs....

Functional differences between rodent and human PD-1 linked to evolutionary divergence A highly conserved motif in human PD-1 but absent in rodent PD-1 is linked to differential inhibitory activity.

A highly conserved motif in human PD-1 but absent in rodent PD-1 is linked to differential inhibitory activity
@scienceimmuno.bsky.social @enfuhui.bsky.social
www.science.org/doi/10.1126/...

Don't miss this fantastic study by @enfuhui.bsky.social & colleagues published this week in #Science #Immunology!

Functional differences between rodent and human PD-1 linked to evolutionary divergence A highly conserved motif in human PD-1 but absent in rodent PD-1 is linked to differential inhibitory activity.

First issue of #Science #Immunology out for 2025! Check out this paper by Masabuchi et al. defining why rodent and human PD-1 function differently!🐀🚶‍♀️@enfuhui.bsky.social
www.science.org/doi/10.1126/...

Thrilled to share our @sciimmunology.bsky.social paper! We report that rodent PD-1 is weaker than human PD-1 (reduced ligand binding & signaling) & lacks a conserved vertebrate motif. Humanizing mouse PD-1 disrupts T cell anti-tumor responses, raising many questions. science.org/doi/10.1126/...