Complement-producing adventitial fibroblasts form an IL-33 alarmin hub that maintains ILC2s during airway allergy Atakkatan et al. identify a distinct subset of C3+IL-33+ adventitial fibroblasts (AFs) that drives allergic inflammation by maintaining ILC2 responses. In turn, ILC2-derived IL-13 supports AF function, thus engaging in a pro-allergic dialogue that promotes type 2 immunity.

Complement-producing adventitial fibroblasts form an IL-33 alarmin hub that maintains ILC2s during airway allergy

Thrilled to share our work that has indeed *complemented* ongoing research in the lab!!!🙌
#complement #IL33 #fibroblast #ILC2 #airwayallergy

Enjoying #AAI2025 and learning a bunch of new science with folks from the lab ! #immunology2025