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Jitse S. Amelink

@jsamelink

PhD candidate Computational neurogenetics @mpi-nl.bsky.social neuroscience x genetics x transcendence x scicomm More on: https://jsamelink.substack.com/

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18.01.2025
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Latest posts by Jitse S. Amelink @jsamelink

Douglas Adams' birthday, time to launch my new business.
Cappuccinome, the coffeeshop of today. On entry you spit in a tube, the barista (a skilled bioinformatician) analyses the DNA, derives your innate taste preferences & delivers a cup of liquid that's almost but not quite entirely unlike coffee.

11.03.2026 13:26 πŸ‘ 22 πŸ” 2 πŸ’¬ 4 πŸ“Œ 0
Should you get relationship advice from your therapist or from the machine gods? – MPI TalkLing

Almost half of Gen Z uses AI for dating advice.

@mpi-nl.bsky.social publicly tested this with social robot Olivia, Chinmaya Mishra and Tila Pronk. Fascinating experience.

I wrote a longread about it for TalkLing:
www.mpi-talkling.mpi.nl?p=2867&lang=en

#AI #LLMs #dating #scicomm #neuroskyence

11.03.2026 15:02 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
a drawing of a monk wearing dark glasses and rolling dice at a table

a drawing of a monk wearing dark glasses and rolling dice at a table

gambling monk, germany, 15th century

10.03.2026 13:15 πŸ‘ 7601 πŸ” 1899 πŸ’¬ 168 πŸ“Œ 381
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Last week, InScience Film Festival visitors could dive into a showcase in human–robot interaction by Chinmaya Mishra and Tila Pronk to a fascinating talk by Koen de Reus on seal communication, and Selim Sametoğlu’s discussion on 'doomscrolling'.

Read the full wrap-up here www.mpi.nl/news/mpi-res...

09.03.2026 13:46 πŸ‘ 5 πŸ” 1 πŸ’¬ 0 πŸ“Œ 1

Follow up on the genetics of chills from art and poetry. This time, including chills from music too 🧡 ⬇️

19.02.2026 19:59 πŸ‘ 20 πŸ” 10 πŸ’¬ 2 πŸ“Œ 0
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AlphaGenome: On the Promise and Limits of AI in Science PHILIP BALL | According to the old story, we once thought that all this other DNA was just β€œjunk,” a term coined in this context in the 1970s. It was accumulated over the course of evolution, for exam...

β€œIt would be foolish to suppose that black box AI can save us from the daunting task of understanding how genomes work. But who would want to forego that anyway, given the intellectual richness & beauty that, for all its messiness, modern molecular biology is revealing?” @philipcball.bsky.social πŸ™ŒπŸŽ―πŸ§ͺ

23.02.2026 16:03 πŸ‘ 21 πŸ” 10 πŸ’¬ 0 πŸ“Œ 2
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God duikt Γ³Γ³k op in de hersenen | Theologie.nl Welke rol speelt ons brein in onze geloofsbeleving? Religie en spiritualiteit bespelen grote delen van het brein in verschillende samenstellingen. AndrΓ© Aleman heeft een helder en nuchter overzicht ge...

God duikt óók op in je hersenen 🧠

Welke rol speelt ons brein in onze geloofsbeleving?

AndrΓ© Aleman heeft een helder en nuchter overzicht geschreven over wat de huidige stand van zaken is in de neurowetenschap van religie. Ik besprak zijn boek met veel plezier

www.theologie.nl/god-duikt-oo...

20.02.2026 09:54 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Roses are red,
Violets are blue,
May your mating be assortative,
With traits well matched to you

14.02.2026 18:22 πŸ‘ 5 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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Genomic insights into substance use and disinhibitory disorders Externalizing spectrum disorders- spanning attention-deficit/hyperactivity disorder, conduct disorder, substance use disorders, and other disorders characterized by disinhibition - frequently co-occur...

Our multi-ancestry GWAS of EXTernalizing conditions (ADHD, substance use...) in ~4M people reveals neurodevelopmental risk, drug-repurposing targets, and yields one of the strongest psychiatric polygenic indices yet! πŸ§¬πŸŽ‰ doi.org/10.64898/202...

11.02.2026 10:33 πŸ‘ 36 πŸ” 18 πŸ’¬ 2 πŸ“Œ 0
Cartoon showing a street in the rain. A man on a bike is delivering food, while another courier is delivering packages from Amazon. Two other workers are collecting garbage. Inside one of the houses on the street, we see robots labeled 'AI' sitting dry and warm, engaged in making a paining, playing the violin and writing.

Cartoon showing a street in the rain. A man on a bike is delivering food, while another courier is delivering packages from Amazon. Two other workers are collecting garbage. Inside one of the houses on the street, we see robots labeled 'AI' sitting dry and warm, engaged in making a paining, playing the violin and writing.

The robot apocalypse hasn't happened yet, but still I can't escape the feeling that something has gone horribly wrong... Cartoon for Dutch newspaper @trouw.nl.

More of my work for Trouw: www.trouw.nl/cartoons/tje...

#ArtificialIntelligence #creativity #work #GenerativeAI

02.02.2026 07:38 πŸ‘ 536 πŸ” 235 πŸ’¬ 9 πŸ“Œ 14
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Why did consciousness evolve at all? A superb special issue of @royalsocietypublishing.org brings together experts across disciplines to explore the functions of consciousness and why it emerged in some species but not others. @tecumsehfitch.bsky.social royalsocietypublishing.org/rstb/issue/3...

08.02.2026 12:47 πŸ‘ 135 πŸ” 51 πŸ’¬ 6 πŸ“Œ 3
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Why does life explore so few of the forms it could possibly take? Using fractal descriptors, this #scienceadvances paper shows that Earth’s biosphere clusters around simple shapes, reflecting deep evolutionary constraints. @artemyte.bsky.social @manlius.bsky.social www.science.org/doi/pdf/10.1...

11.01.2026 13:22 πŸ‘ 229 πŸ” 76 πŸ’¬ 5 πŸ“Œ 6
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When AI hurts the climateβ€”and when it helps | Talking Climate with Katharine Hayhoe Get more from Talking Climate with Katharine Hayhoe on Patreon

Critiques of AI are valid; but many climate-based arguments reveal our bias toward small individual actions over real systemic change.

e.g. ⬇️

An LLM query = running a microwave for seconds
An hour of Netflix = enough to make popcorn

Yet few are boycotting their fav shows.

Interested? Read more:

27.01.2026 14:28 πŸ‘ 134 πŸ” 27 πŸ’¬ 35 πŸ“Œ 10
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Last week, our new paper on indirect assortative mating was published.🍾 Let’s take a closer look at what this means, why it matters, and what we found (🧡/32):

www.nature.com/articles/s41...

11.06.2025 21:51 πŸ‘ 49 πŸ” 21 πŸ’¬ 2 πŸ“Œ 0
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Evaluating the effects of archaic protein-altering variants in living human adults Promise and pitfalls of using large biobanks to study impacts of archaic protein-coding variants in living humans.

While stories of singular DNA changes that drove evolution of human brain/behaviour remain seductive, advances across multiple fields of biology cast doubt on such simplistic narratives of our origins. A new paper from my lab shows how biobanks may speak to this fundamental question.πŸ§ͺ
ExplainerπŸ§΅πŸ‘‡1/n

18.12.2025 13:51 πŸ‘ 116 πŸ” 50 πŸ’¬ 4 πŸ“Œ 14
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Integrating brain structure and function for the neurobiology and genetics of language www.biorxiv.org/content/10.6... New study in which @jsamelink.bsky.social examined brain data from >32,000 people from @ukbiobank.bsky.social ... 1/4 ⬇️

19.12.2025 11:41 πŸ‘ 5 πŸ” 4 πŸ’¬ 1 πŸ“Œ 0
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The missing heritability question is now (mostly) answered Not with a bang but with a whimper

I wrote a little bit about the "missing heritability" question and several recent studies that have brought it to a close. A short 🧡

21.11.2025 22:33 πŸ‘ 351 πŸ” 168 πŸ’¬ 14 πŸ“Œ 22

Super proud of this fabulous team for challenging old comparative frameworks and rethinking what makes language language.
Read more in the thread below πŸ‘‡ or here πŸ“–πŸ˜Š: www.cell.com/trends/cogni...

25.11.2025 23:04 πŸ‘ 30 πŸ” 10 πŸ’¬ 0 πŸ“Œ 3
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What enables human language? A biocultural framework Explaining the origins of language is a key challenge in understanding ourselves as a species. We present an empirical framework that draws on synergies across fields to facilitate robust studies of l...

Origins of language, one of humanity’s most distinctive traits, may be best explained as a unique convergence of multiple capacities each with its own evolutionary history, involving intertwined roles of biology & culture. This framing can expand research horizons. A 🧡 on our @science.org paper.πŸ§ͺ1/n

23.11.2025 11:52 πŸ‘ 206 πŸ” 86 πŸ’¬ 6 πŸ“Œ 10
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Genomic Investigations of Spoken and Written Language Abilities: A Guide to Advances in Approaches, Technologies, and Discovery Purpose: The aim of this tutorial is to show how the rise of molecular technologies and analytical methods in human genetics yields exciting new ...

If you're interested in how advances in human genomics are transforming our understanding of the biology of spoken & written language abilities, please do check out my new peer-reviewed "tutorial" article, just published.
πŸ—£οΈπŸ§¬πŸ§ͺ
[Will also make a Bsky explainer 🧡 on it next week when I get some timeπŸ™‚.]

30.10.2025 15:48 πŸ‘ 18 πŸ” 10 πŸ’¬ 0 πŸ“Œ 0

Better schools can compensate for dispositions

29.10.2025 07:58 πŸ‘ 12 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
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β€˜Change course now’: humanity has missed 1.5C climate target, says UN head Exclusive: β€˜Devastating consequences’ now inevitable but emissions cuts still vital, says AntΓ³nio Guterres in sole interview before Cop30

As the single most important news story this year, I can't wait to see the detailed and central coverage this will get in every media outlet we have

28.10.2025 01:00 πŸ‘ 2051 πŸ” 900 πŸ’¬ 43 πŸ“Œ 66
IMPRS PhD Fellowships 2026 | Max Planck Institute

OPEN PHD POSITION - Come join our group! The IMPRS at @mpi-nl.bsky.social is offering an PhD position on modelling structured meaning in the brain, supervised by me and Helen De Hoop at the Centre for Language Studies in the @dondersinst.bsky.social -
www.mpi.nl/imprs-phd-fe... #NeuroJobs #cogsci

23.10.2025 09:05 πŸ‘ 37 πŸ” 28 πŸ’¬ 0 πŸ“Œ 1

Honestly, highly recommended! Very nice and diverse environment, excellent facilities!

22.10.2025 17:43 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Photograph of researchers at their benches in the custom-built molecular biology labs of the Max Planck Institute in Nijmegen, with green trees of the forest outside visible through large windows in the background.

Photograph of researchers at their benches in the custom-built molecular biology labs of the Max Planck Institute in Nijmegen, with green trees of the forest outside visible through large windows in the background.

Come join us for a 4-year PhD on effects of rare gene disruptions involved in speech disorder, investigated in human neuronal models (via gene-editing, tissue culture, brain organoids, high-res microscopy, transcriptomics, epigenomics).
More info: www.mpi.nl/imprs-phd-fe...
#AcademicJobs #PhDJobs
🧬πŸ§ͺ

22.10.2025 15:42 πŸ‘ 18 πŸ” 21 πŸ’¬ 1 πŸ“Œ 2
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John Searle (1932-2025) - Daily Nous Philosopher John Searle, well-known for his work on philosophy of mind and philosophy of language, has died. John Searle wrote extensively consciousness and the mind, intentionality, and speech act th...

Philosopher of mind John Searle has left the building
dailynous.com/2025/09/28/j...

He was best known for his Chinese Room Argument on artificial intelligence and wide-ranging work on the mind and consciousness

30.09.2025 04:31 πŸ‘ 37 πŸ” 12 πŸ’¬ 1 πŸ“Œ 0

Ode to the original language model, or:
Give me literally Anything* instead of Large Language Models (LLMs)
*(no predictive coding either!)

By Lady Byronadrea LLMartin 1/n

29.09.2025 10:12 πŸ‘ 63 πŸ” 16 πŸ’¬ 2 πŸ“Œ 5
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The phylogenetic position of the Yunxian cranium elucidates the origin of Homo longi and the Denisovans Diverse forms of Homo coexisted during the Middle Pleistocene. Whether these fossil humans represent different species or clades is debated. The ~1-million-year-old Yunxian 2 fossil from China is impo...

At points of our evolutionary history multiple Homo lineages coexisted. Insights into these depend mainly on rare fossil crania, damaged & deformed by age. Removing such distortions, new reconstructions of a 1-million-yr-old cranium from China suggest a surprising mix of primitive & derived traits:πŸ§ͺ

25.09.2025 19:06 πŸ‘ 20 πŸ” 10 πŸ’¬ 1 πŸ“Œ 1
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Musical rhythm abilities and risk for developmental speech-language problems and disorders: epidemiological and polygenic associations - Nature Communications Impaired musical rhythm abilities and developmental speech-language related disorders are biologically and clinically intertwined. Here, the authors explore the correlation between the two traits, finding evidence of epidemiological associations and genetic overlap.

New paper alert! Systematic epidemiological analyses of up to 39,000 people illuminate biological/clinical links between impaired musical rhythm abilities & disorders affecting speech-language development. International collaboration led by @drsrishtin.bsky.social, out in @natcomms.nature.com. πŸ‘‡πŸ§ͺ

25.09.2025 18:17 πŸ‘ 38 πŸ” 15 πŸ’¬ 1 πŸ“Œ 3
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Within-family heritability estimates for behavioural and disease phenotypes from 500,000 sibling pairs of diverse ancestries Quantification of the direct effect of genetic variation on human behavioural traits is important for understanding between-individual variation in socio-economic and health outcomes but estimates of ...

Massive sibling regression study finds that human traits are largely environmentally driven (average heritability = 0.3)

20.09.2025 18:19 πŸ‘ 103 πŸ” 43 πŸ’¬ 2 πŸ“Œ 2