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Jeff Good

@jeffreygood

Evolutionary genomics & speciation of mammals. Prof & Director of the UMontana genomics core. http://www.thegoodlab.org

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17.10.2023
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Latest posts by Jeff Good @jeffreygood

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I Have a Bone to Pick With the Scientists Bringing the Dire Wolf Back From Extinction β€” Slate Come on, do you even know your Game of Thrones lore?

Calm down everyone, apparently Ghost is coming. Probably still working out how to KO the howl.

apple.news/AsPIaHH-wTY6...

08.04.2025 21:52 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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14.03.2025 08:31 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Yes! These days Huey is a strong advocate for conservation research in Montana. One of the good ones for sure!

www.umt.edu/news/2024/07...

10.03.2025 03:24 πŸ‘ 7 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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As DOGE Targets Federal Research, Scientists in Montana Fear Cuts to Critical Programs - Flathead Beacon An air of uncertainty hangs over scientific research in western Montana as the Department of Government Efficiency (DOGE) makes steep cuts to federally funded programs, prompting the region’s leading ...

Local coverage of the impacts of federal #science cuts in western #Montana. πŸ§ͺ

flatheadbeacon.com/2025/03/07/a...

08.03.2025 14:56 πŸ‘ 15 πŸ” 6 πŸ’¬ 0 πŸ“Œ 0

The best!

01.03.2025 17:44 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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US science agency reclassifies hundreds of workers as probationary, US lawmaker says National Science Foundation administrators reclassified hundreds of employees from permanent to probationary status in violation of labor contracts, according to a U.S. lawmaker and agency employee.

"It is absurd to mindlessly decimate the workforce that has led the world in science over the past 75 years, and to willingly give up excellent scientists and talent," Beyer wrote.

www.reuters.com/world/us/us-...

22.02.2025 14:17 πŸ‘ 97 πŸ” 61 πŸ’¬ 5 πŸ“Œ 0

Just be patient and kind to the remaining NSF folks. I promise you, they are still fighting for American science.

19.02.2025 15:21 πŸ‘ 130 πŸ” 26 πŸ’¬ 1 πŸ“Œ 3

Matt I am so sorry to hear this. This is a massive loss for basic science, losing so many talented scientists dedicated to supporting the next big discoveries. Thanks for everything you’ve done, wishing you the best my friend.

19.02.2025 13:54 πŸ‘ 11 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

It's weirdly difficult to remember that Trump's popular vote margin was /less/ than Hillary's in 2016. Biden got more votes in 2020 than Trump got in 2024 and Trump surrogates all under-performed in congressional races.

This is not a mandate, I don't get why it is being portrayed that way.

13.02.2025 20:06 πŸ‘ 12986 πŸ” 1643 πŸ’¬ 949 πŸ“Œ 85

With all the bullshit coming soon, letting rodents predict the weather is going to seem data-driven in comparison.

02.02.2025 15:34 πŸ‘ 475 πŸ” 72 πŸ’¬ 14 πŸ“Œ 3
Evolution of complexity through regulatory variation at a single gene

What do the molecular mechanisms of trait variation tell us about how evolution works?

A great commentary by @mafaldaferreira.bsky.social

www.pnas.org/doi/epdf/10....

Ping @fishcongen.bsky.social @helsinkiuni.bsky.social

29.01.2025 10:29 πŸ‘ 20 πŸ” 7 πŸ’¬ 1 πŸ“Œ 1

Just FYI I’m not quitting

29.01.2025 01:38 πŸ‘ 22 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0

Somebody yelled at me for posting about Ganymede instead of /the state of things/ last night.

I know we’re (almost) all on the same page here, but a Bluesky without cute cats, science facts, and dumb jokes would be bad for everyone.

24.01.2025 17:51 πŸ‘ 63462 πŸ” 3103 πŸ’¬ 2227 πŸ“Œ 315

Preprint finally out! I show that eco-evo feedback can drive a tipping point where genetic drift overwhelms adaptation. This can result in a contraction of a species' range border or range fragmentation. Fragmentation is abrupt and arises readily under rapid temporal change. doi.org/10.1101/2025...

22.01.2025 09:43 πŸ‘ 73 πŸ” 23 πŸ’¬ 1 πŸ“Œ 1
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Love this. And as a consequence aussies are some of the world's most hardcore commuters...

Source www.reddit.com/r/Damnthatsi...

12.01.2025 13:46 πŸ‘ 16 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0
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Very proud to share this outstanding work by @kelsiehunnicutt.bsky.social - now out in Genetics!

03.01.2025 23:12 πŸ‘ 73 πŸ” 25 πŸ’¬ 3 πŸ“Œ 1
Pollination in walnuts (such as this Persian walnut, Juglans regia) and pecans occurs through a genetically controlled temporal flowering dimorphism. Two distinct morphs alternate their phases of male and female flowering across the season, promoting outcrossing that has maintained a stable equilibrium throughout tens of millions of years of evolution. See eado5578.

Photo: Philippe Clement/NPL/Minden Pictures

Pollination in walnuts (such as this Persian walnut, Juglans regia) and pecans occurs through a genetically controlled temporal flowering dimorphism. Two distinct morphs alternate their phases of male and female flowering across the season, promoting outcrossing that has maintained a stable equilibrium throughout tens of millions of years of evolution. See eado5578. Photo: Philippe Clement/NPL/Minden Pictures

It feels surreal to see my PhD research featured on the cover of Science www.science.org/doi/10.1126/.... Incredibly proud of the work that went into this. And so grateful for the opportunities, resources, support and mentorship from co-authors and my whole scientific community that made it possible

03.01.2025 17:44 πŸ‘ 181 πŸ” 26 πŸ’¬ 11 πŸ“Œ 2

Why we fund basic research

21.12.2024 01:25 πŸ‘ 800 πŸ” 191 πŸ’¬ 8 πŸ“Œ 2

Suggestion: Search up Energy Share programs that help people stay warm in the winter. Katherine and I are making a $10,000 donation to Energy Share of Montana today.

15.12.2024 17:10 πŸ‘ 3375 πŸ” 205 πŸ’¬ 47 πŸ“Œ 3

Happy December 13th to all who celebrate!

13.12.2024 14:17 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Local synteny visualization of 3 species and 4 homologous groups.

Local synteny visualization of 3 species and 4 homologous groups.

Local synteny visualization of 5 accessions of beans, highlighting an array of TIR-NBS-LRR genes in this region.

Local synteny visualization of 5 accessions of beans, highlighting an array of TIR-NBS-LRR genes in this region.

A workflow for Tidyverse-based local synteny visualization: Good for visualizing local synteny across species, genotypes, or acorss regions of a genome. Can be used to showcase copy number variation. Still need to write the tutorial, but will be on my GitHub soon. #Genomics #DataVisualization

10.12.2024 20:14 πŸ‘ 75 πŸ” 22 πŸ’¬ 3 πŸ“Œ 2

Yep

07.12.2024 21:24 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

πŸ‘‹ Would love to be included. Not from the global south but here are a few outstanding speciation colleagues that are:

@guillermodelia.bsky.social
@dortizba.bsky.social
@emilyroycroft.bsky.social

07.12.2024 21:23 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

We’ve done faculty searches where we skipped letters altogether and just did phone calls with the shortlist refs. Shifts work to search committee but much better signal to noise. However, some refs *really* disliked this, as if it was a breach in the way things should be. It was illuminating.

07.12.2024 21:00 πŸ‘ 4 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
PhyIN: trimming alignments by phylogenetic incompatibilities among neighbouring sites In phylogenomics, regions of low alignment reliability and high noise are typically trimmed from multiple sequence alignments before they are used in phylogenetic inference. I introduce a new trimming...

A new method for trimming alignments in #phylogenomics β€” PhyIN. It identifies and trims regions with high phylogenetic discord. Able to trim well even on single loci β€” an advantage for gene tree/species tree studies. #evolbiol #phylogeny πŸ§ͺhttp://doi.org/10.7717/peerj.18504 Some backstory... 🧡

06.12.2024 00:56 πŸ‘ 131 πŸ” 50 πŸ’¬ 5 πŸ“Œ 2

Great, let us know if you have questions or suggestions!

04.12.2024 02:34 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

@gwct.bio’s version is much improved, including indels & other improvements. Definitely needs a follow up assessment.

04.12.2024 01:48 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Yes, good idea. Dealing with ref bias in F1s was one of our primary motivations when we first developed this, for genotyping, ASE assignment, etc. Here is an early 2017 pub where we empirically explore some of the biases.

academic.oup.com/gbe/article/...

04.12.2024 01:47 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Releases Β· cooplab/popgen-notes Population genetics notes. Contribute to cooplab/popgen-notes development by creating an account on GitHub.

Just posting this to #popgen
Here's a link to my notes on population & quantitative genetics:
github.com/cooplab/popg...
Hoping to extend it more after the winter holidays, as I'm just finishing up teaching the undergrad version of class.

19.11.2024 23:37 πŸ‘ 361 πŸ” 158 πŸ’¬ 12 πŸ“Œ 1