When AI replaces our work, we will measure wealth by time left.
I would start investing in longevity.
When AI replaces our work, we will measure wealth by time left.
I would start investing in longevity.
The IARC says your >65 ΒΊC tea or coffee is "probably carcinogenic." Studies show up to a 5.6x greater risk of esophageal cancer due to chronic thermal damage, not the caffeine or the drink itself.
β As winter nears, be patient: let it stand and cool.
π pmc.ncbi.nlm.nih.gov/articles/PMC...
This new article confirms it: heat makes us age faster β just as we suspected. Its impact is comparable to other risk factors like smoking, poor diet, lack of exercise, or alcohol.
#Heat #AgingResearch #ClimateChange
www.nature.com/articles/s41...
Glucose spikes have been linked to aging, along with many other diseases. One of the effects of glucose is an increase in body temperature β could this be one of the mechanisms behind its harmful impact?
#Heat #BodyTemperature #Glucose #AgingResearch
link.springer.com/article/10.1...
Taking cold showers is an established anti-aging intervention. There are lots of mechanisms behind this effect, but in the end, it leads to a reduction in body temperature. What about you β have you made this part of your routine?
#ColdExposure #AgingResearch #Intervention #Longevity
One of the most accepted theories of aging involves increasing disorder. Since entropy rises over time β and temperature can accelerate it β could anti-aging interventions work by reducing entropy through lowering temperature?
#Heat #Aging #AgingResearch
Zhao et al, 2022
In vertebrates such as rodents, itβs been shown that they live shorter in hot environments or longer in cold ones. This suggests a clear inverse correlation between lifespan and environmental temperature across different animal models.
#Heat #Cold #AgingResearch
It's known that low temperatures extend lifespan in different animal models β for example, in invertebrates like worms (see image) and flies. Will this be consistent in vertebrate animal models too?
#Heat #Cold #AgingResearch
There is a clear decrease in body temperature with age. Do you think it is a cause or a consequence?
This impressive article analyzes caloric restriction effects on epigenetic aging separating them from lower body temperature. Authors show that caloric restriction alone is not enough to slow down aging β a drop in body temperature is necessary to see these effects.
www.nature.com/articles/s43...
Caloric restriction decreases body temperature, and both factors have been linked to slower epigenetic aging. What would happen if their effects on aging were analyzed separately?
#Heat #BodyTemperature #AgingResearch
Amazing study!The IC clockβbased on DNA methylation changes and linked to lifestyle, and immune and clinical markersβaccurately predicts mortality.Was body temperature considered?Its strong inverse correlation with age could make it a valuable readout in future studies
www.nature.com/articles/s43...
We are not surprised. Studies from around the world report the same pattern: more heat, more miscarriages during the first trimester of pregnancy. Fewer babies are being born in the Q1 of the year. We need new solutions to protect ourselves from rising temperatures. #GlobalWarming #Miscarriage #Heat
As shown in this week The Lancet article, climate change is increasing health problems.It mostly focused on indirect effects of heatβlike poverty, isolation,distress over planet harm.But is anyone asking if heat itself directly causes diseases?We areβcheck our posts
www.thelancet.com/journals/lan...
In camels, the testicles are located close to the body, in the perineal area, protecting sperm from the high desert temperatures. During heat waves, are human testicles too exposed? Are we not as well adapted to heat as camels?
#HeatAdaptation #ReproductiveBiology #AgingResearch
Humans have their testicles outside the body to keep them at a cooler temperature than the core body temperature. But what happens when itβs hotter outside than inside? Are they unprotected? How do other mammals like camels deal with this?
Sperm quality has dropped fast since 2000, and we know that heatwaves make things worse. So how will we protect male fertility from heat?
#Heat #Fertility #AgingResearch
pubmed.ncbi.nlm.nih.gov/38848914/#:~...
Rats and naked mole rats, two similar small mammals, however one lives less than 3-years, the other one more than 30... What could be the key differences that explain such a dramatic gap in lifespan?
#Lifespan #Longevity #AgingResearch
We as humans work with probability. Many interventions, lifestyles are proven to correlate with cancer & shorter lifespans, but we ignore them. Is it because we donβt care, donβt believe, or is it just unawareness? I want to ensure this is known and I will be sharing.
www.nature.com/articles/d41...
Amazing! Congrats I know that time required for work like this. Im fascinated by the observation that T-cells are pro-aging while NSCs pro-rejuvenation...curious, why/how these cells impact their neighbors? signaling, something release?
Very nice initiative from @brunetlab.bsky.social
Growing BlueSky together!
Caloric restriction lowers body temperature. For who practice it, Im curious, do you also cold? its annoying?
www.sciencedirect.com/science/arti....
Very great idea!!
Interested π€
I dont think its just a feeling, its real. Stress makes the people age faster. The open question is why?
I agree, we must avoid overheating our bodies without a justified reason. Stress always increases body temperature , It was selected by nature to fight imminent threats but we pay back ... aging
After reviewing nearly 2,000 interventions that affect lifespan in rodents, Im still intrigued by this report:
Do mice live longer at 21Β°C or shorter at 32.5Β°C?
I would have guessed that the longest-living vertebrate should be aquatic and live in cold water.
I would have guessed that the longest-living vertebrate should be aquatic and live in cold water
hahah I mean more than 37C and no more than 45C
We agree that cold extends lifespan, but does heat lead to death?