Trending
AgingResearch's Avatar

AgingResearch

@agingresearch

Creating an Innovative Cool Aging Project Ph.D 🧬| In Vivo 🐭 | Body Temperature 🌑️ πŸ₯ΆCold vs Heat πŸ₯΅

185
Followers
243
Following
30
Posts
12.12.2024
Joined
Posts Following

Latest posts by AgingResearch @agingresearch

When AI replaces our work, we will measure wealth by time left.

I would start investing in longevity.

20.12.2025 16:09 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

The IARC says your >65 ΒΊC tea or coffee is "probably carcinogenic." Studies show up to a 5.6x greater risk of esophageal cancer due to chronic thermal damage, not the caffeine or the drink itself.
β˜• As winter nears, be patient: let it stand and cool.

πŸ”— pmc.ncbi.nlm.nih.gov/articles/PMC...

06.10.2025 18:01 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
Long-term impacts of heatwaves on accelerated ageing - Nature Climate Change Ageing is linked to environmental factors. This study shows that although participants gradually adapted to heat over time, cumulative exposure to heatwaves had stable and adverse impacts on ageing, e...

This new article confirms it: heat makes us age faster β€” just as we suspected. Its impact is comparable to other risk factors like smoking, poor diet, lack of exercise, or alcohol.
#Heat #AgingResearch #ClimateChange
www.nature.com/articles/s41...

29.08.2025 18:37 πŸ‘ 0 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Preview
Glucose, glycation and aging - Biogerontology Glycation, a deleterious form of post-translational modification of macromolecules has been linked to diseases such as diabetes, cataract, Alzheimer’s, dialysis related amyloidosis (DRA), atherosclero...

Glucose spikes have been linked to aging, along with many other diseases. One of the effects of glucose is an increase in body temperature β€” could this be one of the mechanisms behind its harmful impact?
#Heat #BodyTemperature #Glucose #AgingResearch

link.springer.com/article/10.1...

14.08.2025 08:51 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Taking cold showers is an established anti-aging intervention. There are lots of mechanisms behind this effect, but in the end, it leads to a reduction in body temperature. What about you β€” have you made this part of your routine?
#ColdExposure #AgingResearch #Intervention #Longevity

01.08.2025 13:06 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

One of the most accepted theories of aging involves increasing disorder. Since entropy rises over time β€” and temperature can accelerate it β€” could anti-aging interventions work by reducing entropy through lowering temperature?
#Heat #Aging #AgingResearch

25.07.2025 19:39 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Zhao et al, 2022

Zhao et al, 2022

In vertebrates such as rodents, it’s been shown that they live shorter in hot environments or longer in cold ones. This suggests a clear inverse correlation between lifespan and environmental temperature across different animal models.
#Heat #Cold #AgingResearch

11.07.2025 10:07 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Post image

It's known that low temperatures extend lifespan in different animal models β€” for example, in invertebrates like worms (see image) and flies. Will this be consistent in vertebrate animal models too?
#Heat #Cold #AgingResearch

04.07.2025 12:23 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

There is a clear decrease in body temperature with age. Do you think it is a cause or a consequence?

27.06.2025 16:19 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
A torpor-like state in mice slows blood epigenetic aging and prolongs healthspan - Nature Aging Dissecting the effects of hypothermic and hypometabolic states on aging processes, the authors show that activation of neurons in the preoptic area induces a torpor-like state in mice that slows epige...

This impressive article analyzes caloric restriction effects on epigenetic aging separating them from lower body temperature. Authors show that caloric restriction alone is not enough to slow down aging β€” a drop in body temperature is necessary to see these effects.
www.nature.com/articles/s43...

20.06.2025 11:48 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Caloric restriction decreases body temperature, and both factors have been linked to slower epigenetic aging. What would happen if their effects on aging were analyzed separately?
#Heat #BodyTemperature #AgingResearch

13.06.2025 13:10 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
A blood-based epigenetic clock for intrinsic capacity predicts mortality and is associated with clinical, immunological and lifestyle factors - Nature Aging Fuentealba and colleagues build and validate a DNA methylation clock of intrinsic capacity (IC) to bridge resource-intensive clinical assessments of IC with molecular readouts of aging, highlighting s...

Amazing study!The IC clockβ€”based on DNA methylation changes and linked to lifestyle, and immune and clinical markersβ€”accurately predicts mortality.Was body temperature considered?Its strong inverse correlation with age could make it a valuable readout in future studies
www.nature.com/articles/s43...

06.06.2025 08:51 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Post image

We are not surprised. Studies from around the world report the same pattern: more heat, more miscarriages during the first trimester of pregnancy. Fewer babies are being born in the Q1 of the year. We need new solutions to protect ourselves from rising temperatures. #GlobalWarming #Miscarriage #Heat

30.05.2025 09:50 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
A call to action: the second Lancet Commission on adolescent health and wellbeing Adolescents are the future leaders of our world. Ensuring their health and wellbeingβ€”now and in the futureβ€”is one of the strongest mechanisms available to safeguard the collective future of humanity a...

As shown in this week The Lancet article, climate change is increasing health problems.It mostly focused on indirect effects of heatβ€”like poverty, isolation,distress over planet harm.But is anyone asking if heat itself directly causes diseases?We areβ€”check our posts
www.thelancet.com/journals/lan...

23.05.2025 10:31 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

In camels, the testicles are located close to the body, in the perineal area, protecting sperm from the high desert temperatures. During heat waves, are human testicles too exposed? Are we not as well adapted to heat as camels?
#HeatAdaptation #ReproductiveBiology #AgingResearch

16.05.2025 13:37 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Humans have their testicles outside the body to keep them at a cooler temperature than the core body temperature. But what happens when it’s hotter outside than inside? Are they unprotected? How do other mammals like camels deal with this?

09.05.2025 15:34 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
Impact of heat waves on semen quality: A retrospective study in Argentina between 2005 and 2023 - PubMed Heat waves, defined as periods with daily temperatures surpassing the historical average for a specific region, have become more frequent worldwide in recent years. Previous studies have reported a ne...

Sperm quality has dropped fast since 2000, and we know that heatwaves make things worse. So how will we protect male fertility from heat?
#Heat #Fertility #AgingResearch
pubmed.ncbi.nlm.nih.gov/38848914/#:~...

01.05.2025 11:27 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Post image

Rats and naked mole rats, two similar small mammals, however one lives less than 3-years, the other one more than 30... What could be the key differences that explain such a dramatic gap in lifespan?
#Lifespan #Longevity #AgingResearch

21.12.2024 07:09 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
Why probability probably doesn’t exist (but it is useful to act like it does) All of statistics and much of science depends on probability β€” an astonishing achievement, considering no one’s really sure what it is.

We as humans work with probability. Many interventions, lifestyles are proven to correlate with cancer & shorter lifespans, but we ignore them. Is it because we don’t care, don’t believe, or is it just unawareness? I want to ensure this is known and I will be sharing.
www.nature.com/articles/d41...

20.12.2024 06:44 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Amazing! Congrats I know that time required for work like this. Im fascinated by the observation that T-cells are pro-aging while NSCs pro-rejuvenation...curious, why/how these cells impact their neighbors? signaling, something release?

19.12.2024 06:36 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Very nice initiative from @brunetlab.bsky.social
Growing BlueSky together!

18.12.2024 06:24 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
Caloric restriction and longevity: Effects of reduced body temperature Caloric restriction (CR) causes a reduction in body temperature (Tb) which is suggested to contribute to changes that increase lifespan. Moreover, low…

Caloric restriction lowers body temperature. For who practice it, Im curious, do you also cold? its annoying?
www.sciencedirect.com/science/arti....

17.12.2024 06:54 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Very great idea!!
Interested πŸ€—

17.12.2024 06:42 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

I dont think its just a feeling, its real. Stress makes the people age faster. The open question is why?

16.12.2024 16:24 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

I agree, we must avoid overheating our bodies without a justified reason. Stress always increases body temperature , It was selected by nature to fight imminent threats but we pay back ... aging

16.12.2024 05:45 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Post image

After reviewing nearly 2,000 interventions that affect lifespan in rodents, Im still intrigued by this report:
Do mice live longer at 21Β°C or shorter at 32.5Β°C?

15.12.2024 07:39 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

I would have guessed that the longest-living vertebrate should be aquatic and live in cold water.

14.12.2024 06:18 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

I would have guessed that the longest-living vertebrate should be aquatic and live in cold water

14.12.2024 06:18 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

hahah I mean more than 37C and no more than 45C

13.12.2024 18:49 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

We agree that cold extends lifespan, but does heat lead to death?

13.12.2024 17:45 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0