@damien-glon
Associate Professor at Paris-Saclay University and Institute for Integrative Biology of the Cell 🇫🇷 Team « Autophagy and Antiviral Immunity » Virologist interested in biomolecular condensates induced by viral infections 🦠
🚨Proud to share the preprint from my postdoc in Yves Gaudin’s lab, in collab with Frédéric Rieux-Laucat’s lab.
🧠Our key finding?
NAP1 plays a dual role in regulating innate immunity.
📌This work highlights how phase separation modulates antiviral responses and explains some interferonopathies.
🔗⬇️
NAP1 switches from an activator to a limiter of interferon induction by trapping TBK1 in condensates https://www.biorxiv.org/content/10.1101/2025.05.21.655319v1
Ces recherches ont notamment impliqué des scientifiques de l'Institut de biologie intégrative de la cellule (@i2bcparissaclay.bsky.social - @cea.fr / @cnrs.fr / @univparissaclay.bsky.social / @inrae-france.bsky.social / @inserm.fr), situé à Gif-sur-Yvette (Essonne).
@cnrsbiologie.bsky.social