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Arnaud Le Rouzic

@arnaudlerouzic

CNRS researcher (IDEEV, Université Paris-Saclay, France). Evolutionary genetics, theoretical quantitative genetics, systems biology. Associate editor at J. Evol. Biol. Bridge to my Mastodon account: @arnaudlerouzic.fediscience.org.ap.brid.gy

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16.01.2025
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Latest posts by Arnaud Le Rouzic @arnaudlerouzic

What I just don't get is how authors dare not to check the proposed references. Like "wow, I don't know this paper that seems related to my work, let's have a look at it!". Some of our colleagues seem to ignore the basics of the job.

17.02.2026 14:39 👍 0 🔁 0 💬 1 📌 0

There are sometimes mistakes in public databases (incl. Google Scholar) that might explain additional authors (incorrect first/last name parsing, mixing up authors and editors, etc).

17.02.2026 14:34 👍 0 🔁 0 💬 1 📌 0

Do we really understand how complex systems evolve? Based on experimental evolution in stable vs fluctuating temperature conditions, we show that adaptive mutations in the fungus Zymoseptoria tritici are (i) massively pleiotropic, and (ii) opposed to the phenotypic plasticity.

17.02.2026 08:46 👍 1 🔁 2 💬 0 📌 0

Bonjour Pedro; la mosaïque n'a pas disparu, nous l'avons soigneusement descellée et emportée avec nous dans notre nouveau bâtiment!

15.02.2026 21:22 👍 0 🔁 0 💬 1 📌 0

We were all very sad to learn the death of Pierre Capy. Pierre was a professor at University Paris Saclay, in the 1990s, he started a group working on the evolutionary genomics of transposable elements; this group is still very active today. He was a great teacher, mentor, and colleague.

13.02.2026 13:55 👍 7 🔁 8 💬 2 📌 0

Happy to hare that the preprint I was advertising below has been published by the Journal of Evolutionary Biology:

academic.oup.com/jeb/advance-...

Thanks @jevbio.bsky.social for supporting responsible publishing!

09.12.2025 09:57 👍 28 🔁 22 💬 0 📌 3
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Time to publish responsibly: DAFNEE, a database of academia-friendly journals in ecology and evolutionary biology Abstract. The current economics of scientific publishing reveal a profound imbalance: academia pays prices far exceeding the actual costs of publication. R

Time to publish responsibly: DAFNEE, a database of academia-friendly journals in ecology and evolutionary biology url: academic.oup.com/jeb/article/...

01.12.2025 21:01 👍 43 🔁 24 💬 0 📌 1

The dream of any incompetent scientist: publish in high-profile journals, focusing on "questions", without understanding the technical part. This has *never* worked (e.g., statistics), but it pollutes the literature with bad science.

14.11.2025 10:10 👍 2 🔁 0 💬 1 📌 0
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Have you recently read about a particular field in depth? Perhaps you have just finished your PhD thesis?

@jevbio.bsky.social is seeking Review Articles!

Find out more about Reviews and Target Reviews at JEB here:

academic.oup.com/jeb/pages/re...

23.10.2025 16:37 👍 12 🔁 20 💬 0 📌 1

Very proud to see this work highlighted by the journal! Publishing in Evolution has always meant something special to me. Congrats to the first author Sylvain Pouzet who found the energy to keep on working on his master project during his PhD.

13.10.2025 14:19 👍 12 🔁 3 💬 0 📌 0
Object: Postdoc Position 

Building a phylogenetic model for horizontal transfers of transposable elements 

A postdoctoral position (24 months) is available to work at EGCE (Gif-sur-Yvette, France, CNRS / Université Paris-Saclay) from January 2026. 

Transposable elements (TEs) are repetitive DNA sequences capable of promoting their own mobility. They are widespread across the tree of life and often represent a substantial fraction of eukaryotic genomes. Beyond their ability to invade genomes, TEs are frequently reported to undergo horizontal transfer, enabling their colonization of new hosts. However, understanding and predicting how horizontal transfers shape the distribution of TEs among species is far from straightforward. In particular, estimates of transfer rates based on documented cases are both biased and approximate, since transfers occurring close to speciation events are virtually undetectable. This project aims to develop explicit phylogenetic models of TE evolution that incorporate horizontal transfers, and to use these models to obtain statistical estimates of key evolutionary dynamics of TE families across species (e.g., horizontal transfer and extinction rates). The postdoctoral project will focus on exploring the impact of horizontal transfers on the distribution of TE presence/absence among related species, using statistical and/or computational approaches.

Object: Postdoc Position Building a phylogenetic model for horizontal transfers of transposable elements A postdoctoral position (24 months) is available to work at EGCE (Gif-sur-Yvette, France, CNRS / Université Paris-Saclay) from January 2026. Transposable elements (TEs) are repetitive DNA sequences capable of promoting their own mobility. They are widespread across the tree of life and often represent a substantial fraction of eukaryotic genomes. Beyond their ability to invade genomes, TEs are frequently reported to undergo horizontal transfer, enabling their colonization of new hosts. However, understanding and predicting how horizontal transfers shape the distribution of TEs among species is far from straightforward. In particular, estimates of transfer rates based on documented cases are both biased and approximate, since transfers occurring close to speciation events are virtually undetectable. This project aims to develop explicit phylogenetic models of TE evolution that incorporate horizontal transfers, and to use these models to obtain statistical estimates of key evolutionary dynamics of TE families across species (e.g., horizontal transfer and extinction rates). The postdoctoral project will focus on exploring the impact of horizontal transfers on the distribution of TE presence/absence among related species, using statistical and/or computational approaches.

Context

The position will be part of a 4-year collaborative project funded by the French National Agency (ANR). The research consortium gathers two departments (from Paris-Saclay university and from Université Lyon 1), and involves 7 Pls and 5 postdocs and PhD students devoted to distinct workpackages of the project. The postdoc will be based at EGCE, which is part of the Institute for Ecology and Evolution (IDEEV). The institute offers an exciting and active scientific life, it is located on the new research campus of Paris-Saclay, 35 km south of Paris. 

Relevant references

Gilbert C et al. 2018. Horizontal acquisition of transposable elements and viral sequences: patterns and consequences. Cur. Opin. Genet. Dev. 49:15-24.

Le Rouzic A et al. 2013. Reconstructing the Evolutionary History of Transposable Elements. Genome Biol. Evol. 5:77-86.

Wallau GL et al. 2016. VHICA, a New Method to Discriminate between Vertical and Horizontal Transposon Transfer: Application to the Mariner Family within Drosophila. Mol Biol Evol 33:1094-1109.

Profile

We are looking for a motivated early career theoretical biologist, with a PhD in theoretical evolutionary biology. Skills in statistics, programming, bio-informatics, and phylogenetic models will be appreciated.

Application

Formal applications (CV and cover letter) have to be deposited on the CNRS job portal https://emploi.cnrs.fr/Offres/CDD/UMR9191-ARNLER-006/Default.aspx?lang=EN.

Context The position will be part of a 4-year collaborative project funded by the French National Agency (ANR). The research consortium gathers two departments (from Paris-Saclay university and from Université Lyon 1), and involves 7 Pls and 5 postdocs and PhD students devoted to distinct workpackages of the project. The postdoc will be based at EGCE, which is part of the Institute for Ecology and Evolution (IDEEV). The institute offers an exciting and active scientific life, it is located on the new research campus of Paris-Saclay, 35 km south of Paris. Relevant references Gilbert C et al. 2018. Horizontal acquisition of transposable elements and viral sequences: patterns and consequences. Cur. Opin. Genet. Dev. 49:15-24. Le Rouzic A et al. 2013. Reconstructing the Evolutionary History of Transposable Elements. Genome Biol. Evol. 5:77-86. Wallau GL et al. 2016. VHICA, a New Method to Discriminate between Vertical and Horizontal Transposon Transfer: Application to the Mariner Family within Drosophila. Mol Biol Evol 33:1094-1109. Profile We are looking for a motivated early career theoretical biologist, with a PhD in theoretical evolutionary biology. Skills in statistics, programming, bio-informatics, and phylogenetic models will be appreciated. Application Formal applications (CV and cover letter) have to be deposited on the CNRS job portal https://emploi.cnrs.fr/Offres/CDD/UMR9191-ARNLER-006/Default.aspx?lang=EN.

Come and join our team! A 2-year postdoc position is available in our "Genome Evolution" department at Univ Paris Saclay. We want to play with phylogenetic models accounting for horizontal transfers of transposable elements. Application& details on the official portal: emploi.cnrs.fr/Offres/CDD/U...

24.09.2025 11:45 👍 8 🔁 9 💬 0 📌 3

It is probably worth checking whether this is even compatible with their own copyright transfer agreement. It would be equivalent to e.g. proposing alternative definitions of their own in the margins of published papers, alternative wording, etc. without the author's consent.

18.09.2025 10:03 👍 1 🔁 0 💬 0 📌 0
Maud Tenaillon, Editor-in-Chief of Genome Biology and Evolution: The new GBE logo illustrates how studies on genome evolution can advance our understanding of the emergence of biodiversity and the adaptation of organisms. Both are key questions for addressing current environmental challenges.

Maud Tenaillon, Editor-in-Chief of Genome Biology and Evolution: The new GBE logo illustrates how studies on genome evolution can advance our understanding of the emergence of biodiversity and the adaptation of organisms. Both are key questions for addressing current environmental challenges.

Maud Tenaillon (@maudtenaillon.bsky.social), Editor-in-Chief:

12.09.2025 14:53 👍 7 🔁 2 💬 0 📌 0

To be totally transparent, one needs to consider the hidden cost for the European scientific community to write ~ 4000 40+page grants. Assuming a couple of months of work per grant + many days spent on evaluating them, this is > 1000 years or research from experts lost in this bureaucratic process.

04.09.2025 14:10 👍 0 🔁 0 💬 0 📌 0
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Mike Ritchie emphasising the huge importance of supporting society journals like JEB in his ESEB presidential address, Barcelona. @eseb.bsky.social @eseb2025.bsky.social

22.08.2025 13:58 👍 26 🔁 8 💬 0 📌 0
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We will be in the exhibition hall @eseb2025.bsky.social!

✅ Meet our editors
✅ Support your society journal

@agonzalezvoyer.bsky.social @maxreuter.bsky.social @ebablab.bsky.social @vakirlis.bsky.social @arnaudlerouzic.bsky.social @francescaraffini.bsky.social @masahitotsuboi.bsky.social

11.08.2025 09:01 👍 25 🔁 9 💬 1 📌 3
DAFNEE, a Database of Academia Friendly jourNals in Ecology and Evolution

Ethical scientific journals and where to find them....here is DAFNEE, a #database of non-profit journals in #Ecology and #Evolution #EvoBio, to choose an ethical place where to publish your next articles! (1/2)

dafnee.isem-evolution.fr

🧪 #science

25.06.2025 06:14 👍 101 🔁 42 💬 5 📌 1
Preview
Evolution of plasticity and character displacement in a fluctuating environment

Our paper on evolution of plasticity and character displacement in a fluctuating environment is now published as early view in Evolution. Check it out if you're interested in eco-evolutionary dynamics, coevolution... and plasticity of course!
academic.oup.com/evolut/advan...

26.05.2025 08:13 👍 8 🔁 10 💬 0 📌 0

Very glad to see the second chapter of my PhD published in JEB and feel honored that it has been picked as this month's issue "Editor's choice" and cover image! It's been a long and important team effort leading up to these results!

24.05.2025 12:07 👍 24 🔁 12 💬 1 📌 0

It is frequently believed that cis-regulatory mutations in gene promoters have smaller and less pleiotropic effects than trans-acting mutations in the coding sequence. We could show that this pattern is not a universal truth, as it can only be observed in scale-free regulatory networks.

16.05.2025 13:02 👍 1 🔁 0 💬 0 📌 0
A figure extracted from the scientific paper (https://doi.org/10.1093/evolut/qpaf068). The effect of mutations on fitness depends on the mutation size and the mutation type (Regulatory or Coding mutations). Yet, the network topology (Highly connected, Random, or Scale-free) is a game changer, and conditions which kind of mutation matters the most for fitness.

A figure extracted from the scientific paper (https://doi.org/10.1093/evolut/qpaf068). The effect of mutations on fitness depends on the mutation size and the mutation type (Regulatory or Coding mutations). Yet, the network topology (Highly connected, Random, or Scale-free) is a game changer, and conditions which kind of mutation matters the most for fitness.

Based on simulations, we show that the size and pleiotropy of mutations affecting gene expression heavily depend on the structure of the underlying gene network.

16.05.2025 13:01 👍 1 🔁 0 💬 1 📌 0
A theoretical gene regulatory network, featuring 10 genes connected randomly.

A theoretical gene regulatory network, featuring 10 genes connected randomly.

Very happy to announce the publication of our latest work by my former student Sylvain Pouzet in @journal-evo.bsky.social: "Gene network topology drives the mutational landscape of gene expression".

doi.org/10.1093/evol...

#GeneRegulatoryNetworks
#PopulationGenetics
#EvolutionarySystemsBiology

16.05.2025 12:58 👍 8 🔁 5 💬 1 📌 0
Portail Emploi CNRS - Offre d'emploi - Ingénieur d’études en bio-informatique (H/F)

Job ad: we are looking for a IT/bioinformatician for 12 months, located in the Paris-Saclay campus: emploi.cnrs.fr/Offres/CDD/U...

In French: nous cherchons un ingénieur en bio-informatique (CDD 12 mois) pour de la maintenance serveurs, formation, et assistance utilisateurs.

05.05.2025 08:46 👍 0 🔁 0 💬 0 📌 0
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Why publish in JEB?

✅ Society-owned and not-for-profit model
✅ Dedicated submission support - in-house Managing Editor
✅ Range of article types
✅ Modern Open Science policies - our own Data Editor
✅ Large editorial board with wide-range of expertise

#societyjournal @eseb.bsky.social

09.04.2025 14:00 👍 12 🔁 12 💬 0 📌 2
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Several thousand people today at #standupforscience2025 in Paris.

07.03.2025 19:12 👍 8 🔁 1 💬 0 📌 0
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The Idiot's Guide to Effective Population Size This is a reference manual for the elegant, yet hideously complex concept of effective population size (Ne), inspired by a classic, self-published manual of automotive repair ‘for the compleat idiot’...

Wow. This is sooo good. Echoing @urbanevol.bsky.social this user’s manual for Ne should be required reading for popgen and conservation genetics folks. onlinelibrary.wiley.com/doi/10.1111/...

17.02.2025 18:26 👍 88 🔁 41 💬 1 📌 3

Happy to announce that I have joined the editorial board of the Journal of Evolutionary Biology @jevbio.bsky.social as an Associate Editor. Hope to contribute as much as I can to the journal and to @eseb.bsky.social .

11.02.2025 20:35 👍 8 🔁 2 💬 0 📌 0

SpringerNature keeps on creating new outlet after new outlet... Seems like nothing can stop them.
Just like that joke of a guy putting coins into the soda vending machine: "So long as I'm winning, I'm playing"...

But who pays? We researchers are the fools and we seem to like it.

19.01.2025 16:18 👍 3 🔁 1 💬 0 📌 0