Gloria Vigueras

📢 Lecture at the Faculty of Chemistry (UMU) 👤 Dr. Johannes Karges (Ruhr-University Bochum, Germany) 📅 November 27
Organized by: Grupo Metalofármacos | PhD Program in Basic & Applied Chemistry Co-financed by: Master in Fine & Molecular Chemistry
👉 Don’t miss it! #UMU #Chemistry #Lecture

Thank you, Dori!! 🥹🥹

Congratulations Gloria! A fantastic Feature Article on Type I photorreactivity in Ir/Ru complexes - great to see in @chemcomm.rsc.org. Kudos to @MarchanLab_UB, & teams led by Brabec, Sastre, @gassergroup.bsky.social, @kargesgroup.bsky.social, Nonell, Frances, @eortegaforte.bsky.social

Happy to share that our Feature Article has just been accepted in @chemcomm.rsc.org !🎉
We explore Type I photoreactivity in cyclometalated Ir/Ru complexes. Proud to be corresponding author 💡 @joseruizlab.bsky.social @Marchanlab pubs.rsc.org/en/content/art…

Fe(II) bidentate complexes with long-lived triplet states A series of bidentate quinoline/quinoxaline-NHC ligands were coordinated to an iron(ii) metal centre with the aim of taking advantage of the combined effect of NHC σ-donor and quinoline/quinoxaline π-...

👉 𝐅𝐞(𝐈𝐈) 𝐛𝐢𝐝𝐞𝐧𝐭𝐚𝐭𝐞 𝐜𝐨𝐦𝐩𝐥𝐞𝐱𝐞𝐬 𝐰𝐢𝐭𝐡 𝐥𝐨𝐧𝐠-𝐥𝐢𝐯𝐞𝐝 𝐭𝐫𝐢𝐩𝐥𝐞𝐭 𝐬𝐭𝐚𝐭𝐞𝐬 by Philippe C. Gros 𝘦𝘵 𝘢𝘭.

Fe²⁺ complexes with bidentate quinoline/quinoxaline- #NHC ligands show long-lived triplet states with mixed MC/MLCT character, tunable by ligand structure.

#OpenAccess
🔗 doi.org/10.1039/D5QI01105A

So proud of Dr. Zhong! 🌟 Having my fumehood next to his during my first months in the lab helped me more than he knows. Grateful for this Chinese–Spanish friendship that I'll always treasure and so happy to see him reach this milestone! 🎓✨

A 3D periodic table model by Enrique Barrajón (aka Boolchemist) has been submitted to LEGO 🧪🧱. If it reaches 10K votes, LEGO will consider commercialisation. Support and share to bring it to classrooms! 👉 beta.ideas.lego.com/product-idea...

From August 24–28 2025, the 21st Congress of the European Society for Photobiology (ESP) took place in Bari. The congress provided an opportunity for exchanging ideas, fostering stimulating discussions, and building new collaborations.
@photobiologyeurope.bsky.social

As the #ESPCongress2025 has come to an end, we would like to thank you all for having made this event so unique!!!

The ESP President @pkselbo.bsky.social, the ESP President Elect @frangiunti.bsky.social and the ESP Past President @maxxtrotta.bsky.social are ready to welcome you soon! Safe travels!

Blown away by Sherry McFarland’s talk at #ESPCongress2025 🌟 Incredible to see the full journey of TLD1433 from concept to clinical trials. So much to learn from the photophysical insights—deep diving into these properties is amazing. Grateful for the knowledge! @photobiologyeurope.bsky.social

Super inspired by the first #ESPJunior breakfast with Nobel Martin Chalfie. A powerful reminder of how vital mentors are in science. Lucky to have @joseruizlab.bsky.social as mine during my PhD—thank you for believing in my ideas and helping me grow. #ESPCongress2025 @photobiologyeurope.bsky.social

Check out our paper in J. Med. Chem. @acsbiol.bsky.social @acsmedi.bsky.social about the induction of immunogenic cell death by a gallium complex for chemoimmunotherapy. Congrats to Zisis and Yassin! @ruhr-uni-bochum.de
dx.doi.org/10.1021/acs....

Exploring the toxicity of mononuclear piano-stool Ru(II) anticancer agents: A comprehensive literature review Piano-stool Ru(II) complexes have emerged as a promising class of anticancer agents characterized by structural modularity and diverse cytotoxic activ…

An idea that took root during the COVID lockdown has finally come to life, thanks to the invaluable help of Martin Sojka (former postdoc in our group and now early-career leader at the IPM Brno), who helped me in writing this review on ruthenium(II) piano-stool complexes.

tinyurl.com/yxzshnn5

Our review just got a cover feature!✨
I’m so happy to share it, I had a great time illustrating the cover art! Thanks to Diego for the help!
Metal–coumarin derivatives as promising photosensitizers for cancer phototherapy. @joseruizlab.bsky.social @inorgchemfront.rsc.org

Photoactivatable Cyclometalated Ir(III) Compound Penetrates the Blood-Brain Barrier in 3D Spheroidal and Advanced 3D Organoid Models of Inherently Resistant and Aggressive Brain Tumors The blood-brain barrier represents a significant challenge in delivering anticancer drugs for glioblastoma treatment. The study investigates the potential of a series of octahedral photoactivatable cyclometalated iridium complexes (Ir1–Ir10) with the general formula [Ir(ttpy)(C∧N)Cl]PF6 as photoactivated therapy candidates for the treatment of this aggressive tumor. These complexes, which include the terdentate ligand 4′-(p-tolyl)-2,2′:6′,2″-terpyridine (ttpy), and a C∧N ligand based on the deprotonated 2-arylbenzimidazole backbone, were tested on human glioblastoma using 2D cell cultures and 3D spheroidal models, including a fusion system comprising cerebral organoids from nonmalignant human-induced pluripotent stem cells and spheroids derived from malignant brain cells. The iridium complexes catalyze NADH photooxidation and photogenerate 1O2 and/or •OH under blue light irradiation. Blood-brain barrier penetration was assessed using various in vitro models. The complex Ir4, containing deprotonated methyl 1-butyl-2-phenylbenzimidazolecarboxylate, shows promise for targeted therapy of resistant brain tumors when photoactivated with blue light. Ir4 induces rapid and sustained ROS-mediated cytotoxicity and selectively accumulates in tumor tissue. This suggests its potential for fluorescently guided-PDT cooperative resection of glioblastoma. Notably, Ir4 significantly reduces glioblastoma growth even under dark conditions compared to conventional Temozolomide treatment without affecting healthy brain tissue.

Glad to share our last studies in collaboration with Viktor Brabec.
Photoactivatable Ir(III) Compound Penetrates the Blood-Brain Barrier in 3D Spheroidal and Advanced 3D Organoid Models of Inherently Resistant and Aggressive Brain Tumors | ACS Pharmacol & Transl Science pubs.acs.org/doi/full/10....

Our new work on trans-Pt(II) complexes is out! We've uncovered some unique reactivity – check it out!.https://pubs.rsc.org/en/content/articlepdf/2025/QI/D5QI00674K. #chemistry #chembiol

🚨 Our review "Metal–Coumarin Derivatives as Promising Photosensitizers" is now published in @inorgchemfront.rsc.org!
Huge thanks to @joseruizlab.bsky.social and all co-authors!
🔗https://pubs.rsc.org/en/Content/ArticleLanding/2025/QI/D5QI00858A
#OpenAccess #PDT #HOTarticles

Nice to see our recent article on the Front cover- now published in Inorganic Chemistry Frontiers. doi.org/10.1039/D4QI.... Great collaboration with @MarchanLab_UB.

The only way to find out what was going on was through an old battery-powered radio. That’s how we learned it wasn’t just our city—it was all over Spain. The feeling of being cut off, not knowing what would happen next, was honestly terrifying.+

My mom, who was grocery shopping, had to leave everything behind because she couldn’t pay. And my dad was driving home from work with all the traffic lights out. We were at home, nervous and worried, not knowing if he was okay or if there’d be accidents with the chaos in the streets.+

The only way to find out what was going on was through an old battery -powered radio. That’s how we learned it wasn’t just our city—it was all over Spain. The feeling of being cut off, not knowing what would happen next, was honestly terrifying. +

My mom, who was grocery shopping, had to leave everything behind because she couldn’t pay. And my dad was driving home from work with all the traffic lights out. We were at home, nervous and worried, not knowing if he was okay or if there’d be accidents with the chaos in the streets.+

Excited to share our new @inorgchemfront.rsc.org article about Ruthenium-phosphine complexes as cytotoxic agents against breast cancer. Congrats all team! @ufscar.bsky.social @pesquisafapesp.bsky.social @agenciafapesp.bsky.social

doi.org/10.1039/D5QI...

Next aventure!! Hope u are coming back sooon

I hope I can soon. Thank you, Dori ❤️

Two years of challenges, growth, and incredible people. Paris wasn’t always easy, but I’m proud of everything I’ve learned and overcome. Grateful for those who made this journey special. Thanks to @gassergroup.bsky.social for all I’ve learned during this postdoc. On to the next adventure!

Gracias! :)

Molecular Design Principles for Photoactive Transition Metal Complexes: A Guide for “Photo-Motivated” Chemists Luminescence and photochemistry involve electronically excited states that are inherently unstable and therefore spontaneously decay to electronic ground states, in most cases by nonradiative energy release that generates heat. This energy dissipation can occur on a time scale of 100 fs (∼10–13 s) and usually needs to be slowed down to at least the nanosecond (∼10–9 s) time scale for luminescence and intermolecular photochemistry to occur. This is a challenging task with many different factors to consider. An alternative emerging strategy is to target dissociative excited states that lead to metal–ligand bond homolysis on the subnanosecond time scale to access synthetically useful radicals. Based on a thorough review at the most recent advances in the field, this article aims to provide a concise guide to obtaining luminescent and photochemically useful coordination compounds with d-block elements. We hope to encourage “photo-motivated” chemists who have been reluctant to apply their synthetic and other knowledge to photophysics and photochemistry, and we intend to stimulate new approaches to the synthetic control of excited state behavior.

A simple guide to the design of metal complexes in luminescence and photoredox catalysis.

With Giacomo Morselli and Christian Reber in JACS @jacs.acspublications.org

pubs.acs.org/doi/10.1021/...

¿Puedes añadirme? Gracias 😊

Read our paper in @acsjacs.bsky.social! @acs.org

The Babak Lab 🤝 Prof. Ang Wee Han, Prof. Walter Berger and City University of Hong Kong!

#chemsky