Excited to share our latest work from first author Patrick Woida. Using a novel surface display platform for expression of split TurboID, we discovered that CYLD is recruited to the Listeria surface via the effector InlC and that it supports cell-to-cell spread www.biorxiv.org/content/10.6...
With CauloCon coming up in a few weeks, we are excited to share with you the schedule for the upcoming meeting! There will be 3 keynotes and 26 short talks over three days.
You can see more information at caulocon.com
Notice of Temporary Extension of Eligibility for the NIH Pathway to Independence Award (K99/R00):
for Individuals whose final due date was September-November 2025 and January-March 2026. As always, reach out to your PO/IC contact to discuss.
grants.nih.gov/grants/guide...
Check out our latest paper from first author Allison Scott using a powerful enrichment strategy to enable transcriptional profiling of the early stages of a rickettsial infection
This project has been incubating for a while, and I'm very grateful to my labmates who pitched in (@laurenbird.bsky.social and others not on 🟦), @johndoench.bsky.social, and my amazing mentor @lamasonlab.bsky.social. More to come soon!
First 🟦 post - my main postdoc work is out in the world! We designed a Cas12a-based genetic screen to identify host factors that contribute to infection by the tickborne pathogen Rickettsia parkeri, and stumbled across a really exciting direct interaction between host and bacterium🦠. Check it out!
Thrilled to contribute to this exciting work on protein binder design together w/ @hannes-stark.bsky.social
, Felix Faltings, Regina Barzilay, Tommi Jaakkola, and co. We applied BoltzGen to design novel antimicrobial peptides targeting DNA gyrase based on inhibitory protein fragments. (1/n)
Thrilled to share my work from the @jkagan1.bsky.social lab!
TLDR: O-acetylation and wall teichoic acid compete for space on S. aureus peptidoglycan. This competition regulates DNA release, and thus immune receptor activation, during infection!
www.biorxiv.org/content/10.1...
#microsky #immunosky
1/ Excited to share the first preprint from my lab! 🎉
My postdoc Paz asked how cholera toxin (CT) helps Vibrio cholerae thrive in the gut.
Turns out, CT rewires epithelial metabolism toward L-lactate production—fueling pathogen growth in the small intestine during disease
Poster of diverse scientists chatting with each other and holding idea balloons representing various fields in the life sciences, such as DNA, cells, gears, and lightbulbs. More information is available through the QR code.
Are you an MIT postdoc in the life sciences? Come join my new initiative, the KendallSqBio Postdoc Symposium on Sept. 10, 2025!
✅ Present your science
✅ Connect with other postdocs
✅ Build your community
Abstract deadline July 11th! forms.gle/iXMTYfqgLKWR...
Alert! The abstract deadline for the Microbial Pathogenesis & Host Response meeting has been extended to July 7 meetings.cshl.edu/meetings.asp...
Excited to share this story from my PhD, out today in Nature Communications! We show that Coxiella removes cathepsin B to reduce lysosomal hostility and promote bacterial success. This depends on a vacuole established by effector CvpB.
www.nature.com/articles/s41...
Excited to see many in the bacterial pathogenesis community joining here in the last few weeks, so here's a Starter Pack to help make connections. Reply/DM to be added to this or future Packs. #Microsky go.bsky.app/VH64BaY
go.bsky.app/L3L2iFz
