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Pauline Morigny

@morignypauline

Post-doctoral researcher at the Institute for Metabolic and Cardiovascular Diseases (I2MC), Inserm, Toulouse, France

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26.02.2025
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Latest posts by Pauline Morigny @morignypauline

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Multi-omics profiling of cachexia-targeted tissues reveals a spatio-temporally coordinated response to cancer - Nature Metabolism Multi-omics profiling of diverse cancer cachexia models uncovers a multi-tissue metabolite-coordinated response associated with disease progression and links multi-tissue one-carbon metabolism to wasting.

RESEARCH
@morignypauline.bsky.social
@ondrej-kuda.bsky.social M Rohm (CAS, Helmholtz Munich)

Multi-omics profiling of cancer cachexia models uncovers a multi-tissue coordinated responseπŸ§ͺ

24.02.2026 21:02 πŸ‘ 10 πŸ” 7 πŸ’¬ 0 πŸ“Œ 0
Preview
Multi-omics profiling of cachexia-targeted tissues reveals a spatio-temporally coordinated response to cancer - Nature Metabolism Multi-omics profiling of diverse cancer cachexia models uncovers a multi-tissue metabolite-coordinated response associated with disease progression and links multi-tissue one-carbon metabolism to wast...

This work is the result of a collaboration between the groups of Maria Rohm @helmholtzmunich.bsky.social and @ondrej-kuda.bsky.social (CAS, Prague). I would like to thank all co-authors and reviewers.
Paper here πŸ‘‡
www.nature.com/articles/s42...

15.01.2026 11:50 πŸ‘ 7 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0

I am proud to share our multi-omics study in cancer cachexia out in @natmetabolism.nature.com πŸ¦€ Through metabolomics, transcriptomics and glucose tracing of multiple cachexia target tissues, we uncovered a metabolic pathway with pro-cachectic potential.

15.01.2026 11:50 πŸ‘ 3 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
Weight Loss in Cancer: Coordinated Multi-Organ Response

Weight Loss in Cancer: Coordinated Multi-Organ Response

Weight Loss in Cancer: New research led by #HelmholtzMunich shows that #cachexia affects multiple organs in a coordinated metabolic way, not just muscles.

πŸ‘‰ Read more: t1p.de/q0ukw

@ondrej-kuda.bsky.social
@iphys-cas.bsky.social
@diabresearch-dzd.bsky.social
@dzhk.de

15.01.2026 10:09 πŸ‘ 1 πŸ” 4 πŸ’¬ 1 πŸ“Œ 0

New paper from our institute showing the importance of liver secretory function on the development of cancer cachexia. Congratulations to @dorie00.bsky.social , SΓΆren Fisker Schmidt, Mauricio Berriel Diaz and Stephan Herzig ! Very proud to have contributed to this amazing story πŸ₯³

25.07.2025 07:02 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

πŸ“£ Check out our recent preprint on bioRxiv on cellular changes in adipose tissue in response to different weight loss modalities πŸ“£

06.03.2025 09:52 πŸ‘ 9 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0

Hi Bluesky ! πŸ¦‹

26.02.2025 13:42 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0