Binyam Mogessie ቢንያም ሞገሴ

Let's get this hashtag started! The 2026 Santa Cruz Developmental Biology Meeting is happen this August! We will share updates using #SCDB26.

Can't wait!

scdb2026.sites.ucsc.edu

wonderful Takashi!! Congrats to you and your team!

Hybrid female sterility due to cohesin protection errors in mouse oocytes Misregulation of chromosome cohesion during female meiosis serves as a reproductive isolating barrier in mice.

Another announcement! 📣 Our work on hybrid incompatibility in cohesin protection in 🐭oocytes is published!! Congrats Warif El Yakoubi and Eddie Pan!!🎉 We found hybrids with cohesion errors in two distinct genus.
www.science.org/doi/10.1126/...

The Reck-Peterson lab at Weill Cornell Medicine is seeking a technician or staff scientist to work on Aspergillus projects. Broad background in fungal biology and techniques required. Bioinformatics skills preferred. Find out more at: reckpetersonlab.org.

SAVE THE DATE! Stoked to organize the 2026 Santa Cruz Developmental Biology Meeting with @rashmi-priya.bsky.social, @lowelab.bsky.social, and Shelbi Russell. Come learn about Biomedicine, Biomechanics, and the Biosphere, August 24-28, 2026. Registration dates, etc., coming soon! Please RT

this sucks

A versatile cohesion manipulation system probes female reproductive age-related egg aneuploidy - Nature Aging To study pathways that lead to aneuploidy during aging, the authors provide a system that enables cohesion protein depletion in mouse oocytes, mimicking effects that occur during aging. They uncover a...

We built a targeted protein degradation–based system to mimic reproductive age-related aneuploidy in young eggs - revealing how chromosome errors associated with female infertility arise with age. 🧬✨
With @jiyeonleem.bsky.social and our team at Yale MCDB.

Read: www.nature.com/articles/s43...

We hire!
The CytoMorpho Lab is looking for an engineer with a background in cell and molecular biology to join our team in Paris. This is a 18-month contract position, but we're open to exploring long-term opportunities.
More details here:
cytomorpholab.com/index.php/jo...

Thank you for having me, I had a wonderful visit!!

True that Manuel! thanks for calling this out.

Congratulations Aaron, such great news!!

Happy Birthday YouTube video by Busy Signal - Topic

Happy birthday @needhibhalla.bsky.social

music.youtube.com/watch?v=E5GZ...

*chromosome arm-specific removal of REC8

We built an experimental system for manipulation of oocyte chromosome cohesion using PROTACs, mimicking within 1.5 hrs chromosomal abnormalities that naturally arise over years to decades. BONUS: we visualized by live imaging chromosome arm-specific and centromeric retention of REC8 during anaphase!

A versatile cohesion manipulation system reveals CENP-A dysfunction accelerates female reproductive age-related egg aneuploidy. Female reproductive aging is accompanied by a dramatic rise in the incidence of egg aneuploidy. Premature loss of chromosome cohesion proteins and untimely separation of chromosomes is thought to unde...

Some good news during these difficult times. Please check out our new preprint. We built a new tool to probe the origins of high oocyte aneuploidy rates at advanced female reproductive ages. This NIH funded work was led by a fantastic postdoc in the lab, Jiyeon Leem. www.biorxiv.org/content/10.1...

Many congratulations Sam! Wonderful news🥳

Sharing some oocyte spindle love-an image taken by PhD student Phia Maddocks. This beautiful work is supported by our NIH funding. Without this funding, we cannot understand the complexities of fertility genetics. With declining fertility rates, this work is essential to human health.

This is couple of years old since I rarely have time to sit at a scope these days but I was inspired by the end of year #FluorescenceFriday posts on hear and thought I should drop on y’all my Eye of Sauron, aka a mouse oocyte containing nuclear actin filaments #actin #meiosis #oocytes

Molecular mechanism targeting condensin for chromosome condensation | The EMBO Journal imageimageHow the condensin complex is recruited to genomic domains to promote their condensation is incompletely understood. This study identifies a generalised molecular mechanism by which condensin...

Happy to see this out before the end of the year. Fantastic work by Lily Wang with help from our wonderful technologists in the Discovery Platform Proteomics Core managed by Christos Spanos. Great publishing experience @embojournal.bsky.social www.embopress.org/doi/full/10....

On the origin of mitosis-derived human embryo aneuploidy Nature Communications - Chromosome segregation errors are common in the early stages of human embryonic development. By examining the first mitotic divisions of human embryos using live cell...

Chromosome segregation errors are common in the early stages of human embryonic development. Read here our open access commentary on three recent studies of spindle architecture and positioning features that
could provide insights into why early embryos are predisposed to aneuploidy.
rdcu.be/d1TgG

My lab came as me for Halloween…i’m proud 🥹

Yale University and the Department of Molecular, Cellular and Developmental Biology is looking for Assistant Professor in Plant Biology and Assistant Professor in Systems Biology.
#neurojobs
#neuroscience l🧪l🧠📊l🧠🖥️
#academicsky
#statsky
#physics
mcdb.yale.edu

The Department of Molecular, Cellular and Developmental Biology at Yale University is looking for a

Tenure-track Assistant Professor in Plant Biology

mcdb.yale.edu

PDF:
mcdb.yale.edu/sites/defaul...

#PlantSciJobs

FEED for Plant Science Jobs here:

bsky.app/profile/did:...

Come be my colleague! The MCB Department at UConn is looking for a TT Assistant Professor in the broad fields of structural biology, biophysics, and biochemistry. Collaborative department, strong graduate program, and state of the art core facilities. academicjobsonline.org/ajo/jobs/25945

cant wait😊

Excited to host @binyammogessie.bsky.social at UConn MCB tomorrow! Looking forward to nerding out about eggs and chromosomes 🧬🔬🥚