Sairam Jabba

NASA Says Mars Rover Discovered Potential Biosignature Last Year - NASA A sample collected by NASA’s Perseverance Mars rover from an ancient dry riverbed in Jezero Crater could preserve evidence of ancient microbial life. Taken

BREAKING NEWS: NASA has found a potential sign of past life on Mars. www.nasa.gov/news-release...

No place for political violence in this country or anywhere.

FDA Urges Nicotine Pouch Manufacturers To Use Child-Resistant Packaging Following Increasing Reports of Accidental Exposure The U.S. Food and Drug Administration calls on nicotine pouch manufacturers to use child-resistant packaging to protect American children from accidental, harmful exposure.

#TobRegSky #TobRegSci
FDA Urges Nicotine Pouch Manufacturers To Use Child-Resistant Packaging Following Increasing Reports of Accidental Exposure

www.fda.gov/news-events/...

Elevated Toxic Element Emissions from Popular Disposable E-Cigarettes: Sources, Life Cycle, and Health Risks The rapidly evolving market of disposable e-cigarettes poses unknown health risks to adolescents and young adults. We report excessive emissions of toxic metallic elements in aerosols from flavored an...

#TobRegSky #PedSky #MedSky #EpiSky #addictionsci #policysky #polisky #neuroskyence #neurosci 🧪🛟

Lead, nickel and antimony at toxic levels in vapor from disposable e-cigarettes

pubs.acs.org/doi/10.1021/...

We finally have an impact factor at Neurobiology of Pain. Thanks to our editorial team: Michael Burton, @annatheneurosci.bsky.social, and Dave Seminowicz; the editorial board; and all our wonderful authors for submitting such great papers over the past several years.

“Findings support an educational model that delays AI integration until learners have engaged in sufficient self-driven cognitive effort. Such an approach may promote both immediate tool efficacy and lasting cognitive autonomy,”

Brain’s performance during, after exclusive ChatGPT usage drops, results in weaker neural connectivity While exclusively relying on ChatGPT showed concerning outcomes, participants who wrote essays without any assistance and then began using ChatGPT showed higher memory recall, efficient tool use, s…

A new study comparing AI tools engagement & memory encoding indicates that brain’s performance during and after exclusive ChatGPT usage drops, results in weaker neural connectivity

sciencechronicle.in/2025/06/23/b...

If any of you are at #CPDD2025 head over to Grand Ballroom A today at 10.30 AM for an exciting symposium on Emerging challenges in #Tobacco regulation from synthetic additives
Great line of speakers
#AlaynaTackett @hanno-ery.bsky.social #SuchitraKrishnan-Sarin @drbhenderson.bsky.social
& Urs Truly

In Good Health: The latest on vaping regulations Disposable nicotine vapes in fruity flavors are easy to find but technically illegal.

#TobRegSky
An interesting discussion on @npr.org 1A re: the need for more comprehensive e-cig regulations, esp. in the context of novel innovations & chemical constituents.
Thanks @sarah-todd.bsky.social for highlighting our @jama.com studies on #Neotame & #NicotineAnalogs

the1a.org/segments/in-...

#CannabisScience
Assessing risk of urologic malignancy after cannabis abuse/dependence using population-level analysis of national database (>100 mil patients) @USC study finds
• ~4-fold increased risk of bladder & kidney cancer
• ~3-fold increased risk of prostate cancer
doi.org/10.1016/j.ur...

#TobRegAky
Very informative article by @LisaO’Mary of @webmd.com re: addition of ultra-potent sweetener Neotame in E-cigs.
Expert commentary by @sejordt.bsky.social @ruchimathurmd.bsky.social & @HavoviChichgar

www.webmd.com/diet/news/20250606/the-next-gen-sweetener-you-may-be-eating-and-inhaling

From the makers of Zyn. How is this Rocket Pop Cigar ok? Who knew summer could taste like a carcinogen?

#TobRegSky #PedSky #MedSky #EpiSky #addictionsci #policysky #polisky #neuroskyence 🛟
Chinese e-cigarette manufacturers are in an arms race, marketing disposable devices with bigger and bigger e-liquid reservoirs. The first device capable of delivering 100,000 puffs was just introduced.

Very soon you will have a Million puff vaping device and will still be unregulated. Only half- joking.

The ubiquitous presence of the ultra-potent artificial sweetener #Neotame (upto 13,000X potent than sugar) in disposable e-cigs along with its unknown impact on e-cig addiction & toxicity is concerning.
Extremely proud to co-lead this @jama.com study with the incredible #HannoErythropel of #YaleU.

What makes your kids tolerate the yucky Tylenol?
Ton of sugar+sweeteners.
Similarly tobacco products are 'sweetened' historically to make them palatable.
In this new @jama.com article we show the addition of #NEOTAME, an ultra potent sweetener, to majority of popular disposable e-cigs in the USA.

#TobRegSky #PedSky #MedSky #addictionsci #neuroskyence #policysky #polisky #episky🛟

In @nytimes.com : Trump Budget Cuts Hobble Antismoking Programs

Thanks, @by-cjewett.bsky.social , for the interview.

Nicotine Pouch and E-Cigarette Use and Co-Use Among US Youths in 2023 and 2024 This cross-sectional study examines the prevalence of and sociodemographic variables associated with nicotine pouch and e-cigarette use among US youths in 2023 and 2024.

‪ #TobRegSky‬ #PedSky #MedSky #EpiSky #policysky #polisky #addictionsci 🧪🛟

Nicotine pouch use of US youth almost doubled from 2023-24.
jamanetwork.com/journals/jam...

‪ #TobRegSky‬ #PedSky #MedSky #EpiSky #policysky #polisky #addictionsci 🧪🛟
Former FDA Center for Tobacco Products Director Brian King assumes leadership position at @tobaccofreekids.bsky.social . Congratulations !

Sugars in Tobacco Products: Toxicity Research and Implications for Tobacco Product Regulation Sugars are naturally present in tobacco plants and are introduced as additives during the manufacturing of various tobacco- and nicotine-containing products. Product palatability and appeal are the primary reasons for manufacturers’ attention to the sugar content in tobacco and nicotine products. However, because of the complex chemistry of sugars and their thermal decomposition, these versatile constituents are also contributing to the toxicity profile of tobacco and nicotine products. Using published empirical data, this non-systematic review summarizes the state of knowledge on the toxicologically relevant chemical transformations of sugars and artificial sweeteners in tobacco and nicotine products, including waterpipe tobacco, combustible and electronic cigarettes, heated tobacco products, and smokeless tobacco, and available research on the associated health effects of sugar-derived toxicants. Implications of sugar and sweetener content for abuse liability of various tobacco products are also discussed. Based on the findings of this review, research gaps are identified and policy recommendations are made for regulating sugars and artificial sweeteners in tobacco and nicotine products, including adding sugars and artificial sweeteners to the list of harmful and potentially harmful constituents (HPHCs).

#TobRegSky #PedSky #MedSky #addictionsci #policysky #polisky #neuroskyence #neurosci 🧪🛟 🫁

Coauthored by the awesome @sairamjabba.bsky.social !

Sugars in Tobacco Products: Toxicity Research and Implications for Tobacco Product Regulation
pubs.acs.org/doi/10.1021/...

Policy makers and regulators should work towards limiting high-nicotine and ultra-nicotine e-cigarette sales that could protect US youths.

Thanks, @sotoxicology.bsky.social , for scheduling our Hot Topic session on unregulated nicotine analogues !! Great audience questions and lively discussion of regulatory issues.

Nicotine Concentration of E-Cigarettes Used by Youths This cross-sectional study investigates rates of nicotine concentrations vaped by US youths and associated substance use characteristics.

New @jama.com study by @adam-leventhal.bsky.social group #USCTCORS show
>HS Student use of high nicotine strength e-cigs was assoc. with more days of vaping & poly-substance use
>4/10 students were unsure of the nicotine conc. in their vapes
@alyssaharlow.bsky.social jamanetwork.com/journals/jam...

Please tobacco control community! please repost the JAMA post below! trying to demonstrate to our university leadership the value of adding a @bsky.app "share buttons" on university science press releases!

Happening right now at #SOT2025
Room 308A
130-3pm
@dreffah.bsky.social @sejordt.bsky.social

Join our Wed 1:30 pm #2025SOT @sotoxicology.bsky.social

Hot Topic Session:

Unregulated Synthetic Nicotine Analogues in E-cigarettes and Oral Products: An Emerging Public Health Threat?

Room W308A

with: @sairamjabba.bsky.social @dreffah.bsky.social
and Dan Conklin @uoflenvirome.bsky.social !!

Last day of #SRNT2025
The last pre-clinical/basic science research session for the meeting
Title: Pre-Clinical Advances in Nicotine and Tobacco Research
Time: 9:45 AM - 11:15 AM
Salon 9-12

Chaired by @drbhenderson.bsky.social and @sejordt.bsky.social
with fantastic speaker list: #HannoErythropel #DenizBagdas from #YaleU @sairamjabba.bsky.social from #DukeU, @drbhenderson.bsky.social #AlaynaTackett from The Ohio State and #ReinskjeTalhout from RIVM Netherlands

Symposium details

#SRNT2025 Symposium 13 today afternoon
Lab-Made Challenges to Tobacco Regulation: Chemistry, Pharmacology, and Reinforcing Properties of Nicotine Analogues & Other Synthetic Additives
Talks will be combination of topics: Chemistry, Pre-Clinical, BasicSci, Human Studies, Risk assessment & regulation