Interesting case of necrotizing vasculitis in a lupus patient. Hx of LN in prior biopsies, no active GN features now. May be lupus vasculitis, but recommend r/o superimposed vasculitic disease (e.g., ANCA, drugs) with such biopsies findings. #renalpath #nephsky #pathsky
Image Quiz! A 4 year old boy presented with pigmented macules around the lips and oral mucosa, gynecomastia and the findings shown on the testis biopsy here. What diagnosis is most associated with this case?
(Continued in thread)
#Pathology #PathologyOutlines #Diagnosis #PathSky
We recently appointed several new editors to our Editorial Board!
Read about them here: buff.ly/LH9NI3k
Our Boards: buff.ly/gJFmEiH
#Pathology #Textbook #PathologyOutlines #PathSky
The Renal Pathology Society warmly invites nephropathologists and non-pathologists involved in the interpretation of kidney biopsies to participate in a global survey.
More info. below 👇
renalpathsoc.org/RPS-Internat...
@glomcon.org @theisn.org #renalpath #pathsky #nephsky
Multi-focal severe necrotizing arteritis in a kidney biopsy with an ANCA vasculitis. Interestingly, foci of arteritis were only present in IF/EM tissue. Illustrating how even when severe arteritis can be easily missed due to sampling in a small biopsy. #renalpath #nephsky #pathsky
Course Director Dr. Alexandros D. Polydorides provided this quick case overview for us.
my.uscap.org/app/program/...
Clinical history: 67 F with prior appendectomy, now presenting with an implant in the mesentery of the jejunum.
#PathSky
Excuse the “taking a picture of a computer screen” quality here - this looks like early MN pattern (IgG, IgG1 here) by IF, but EM has absolutely no deposits (EM on frozen material done on this glom). Still MN (“by IF only”?!)? @glombandit.bsky.social @arkanalabs.bsky.social @jzrenalpath.bsky.social
We are looking for a 3rd renal pathologist to join our team here at UCLA. Please see the job description here: recruit.apo.ucla.edu/JPF10146. It's a great department and LA is a great city. #renalpath #pathsky
A polyoma virus 'crescents' in a case of BK nephropathy in a kidney transplant patient. SV40 demonstrates parietal epithelial cell positivity on deeper levels. BK viremia >3 million recently. #renalpath #pathsky #nephsky
"If you are only going to do 1 biopsy, do the second" - Gary Hill
Rovin et al get the 2nd kidney bx in this lupus nephritis study using voclosporin and did not find CNI toxicity
acrjournals.onlinelibrary.wiley.com/doi/abs/10.1...
Website Update ✨ Going forward, sample questions in our topics will be termed "Practice questions." These were formerly called "Board review style questions."
Learn more: pathologyoutlinesblog.wordpress.com/2025/04/25/2...
#Pathology #PathologyOutlines #PathSky
Will you be at USCAP in Boston next week? Visit us at Booth #840!
Find out what awaits you at our booth: buff.ly/8G6UPkm
#Pathology #PathologyOutlines #USCAP #USCAP2025
A cute finding in apocrine metaplasia, do you know what it is? #breastpath #pathsky #pathtwitter #pathx #patologia
Pronase IF can be very helpful in cases of cryo-GN as the frozen IF is often masked. This case also showed classic hyaline pseudo-thrombi, cryo-vasculitis, and microtubules by EM. #renalpath #pathsky #nephsky
Several CDC websites and datasets related to HIV, LGBTQ people, youth health behaviors and more have been removed after the agency was directed to comply with an executive order from President Donald Trump.
All the time! Very annoying indeed
As an expert on death, I’m stating the obvious by saying #DEI has no role in air traffic fatalities.
Also, aviation is one of the least diverse professions - <5% of commercial pilots are women and >90% of pilots and flight engineers are from non-ethnic backgrounds.
Yet another baseless claim..😒
Case of the Month: An 82 year old female patient presented with a 3.5 cm sized, well circumscribed, nodular skin lesion on the cheek showing the following histomorphologic and immunohistochemical findings. What is your diagnosis?
Select the link in the comments for the case!
Image of the Week!
Submitted by: Nurul Bahiyah Binti Baharudin, M.D.
Directory Profile: https://buff.ly/40OGjAR
Subspecialty: Dermatopathology
Diagnosis: Sporothrix asteroid bodies
#Pathology #PathologyOutlines #DermPath
What I'm looking for in #placenta membranes:
MVM incl
. Decidual arteriopathy
. Mural hypertrophy
. Atherosis and fibrinoid necrosis
H&E micrograph of placenta membrane showing acute chorioamnionitis, MIR stage 2
Maternal inflammatory response stage 2, acute chorioamnionitis - more than a few neutrophils in the fibrous chorion and amnion. I need to see subchorio as well.
Example of necrotizing lupus vasculopathy. Hilar arterioles with luminal immune complex deposit and mural necrosis. Ig deposition in lumen of vessel and fibrinogen staining by IF. #renalpath #pathsky #nephsky
