Thomas Jaki's Avatar

Thomas Jaki

@thomasjaki

Professor of Statistics at University of Regensburg and University of Cambridge

251
Followers
106
Following
13
Posts
25.10.2024
Joined
Posts Following

Latest posts by Thomas Jaki @thomasjaki

Preview
A digital imagery-competing task intervention for stopping intrusive memories in trauma-exposed health-care staff during the COVID-19 pandemic in the UK: a Bayesian adaptive randomised clinical trial Psychological trauma, such as witnessing an untimely or gruesome death, commonly provokes intrusive memories that might persist for days to years with…

New paper in The Lancet Psychiatry, with @thomasjaki.bsky.social as co-author, about the GAINS-2 Trial - A Bayesian adaptive randomised trial which uses a digital intervention to combat the trauma UK healthcare workers experienced during the COVID-19 pandemic.

www.sciencedirect.com/science/arti...

23.02.2026 11:42 πŸ‘ 0 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Statistical Analysis with Missing Data Using Multiple Imputation | LSHTM

@lshtm.bsky.social will be running a 3-day online short course on using multiple imputation to handle missing data on 23-25th June 2026. Teaching staff include James Carpenter, Ruth Keogh, ClΓ©mence Leyrat, and myself. Further details about the course at www.lshtm.ac.uk/study/course...

06.01.2026 09:37 πŸ‘ 15 πŸ” 11 πŸ’¬ 1 πŸ“Œ 1
Infographic illustrating basket trials.

Infographic illustrating basket trials.

Libby Daniells from the BSU and colleagues have developed a new technique to improve the reliability of #ClinicalTrials.

Read more πŸ‘‡
www.mrc-bsu.cam.ac.uk/news/incorpo...

Paper in Biostatistics πŸ‘‡
academic.oup.com/biostatistic...

03.12.2025 17:06 πŸ‘ 4 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

Yesterday I received a grant rejection. Obviously very disappointed, but at least one of the reviewers recognised that I was a young researcher with potential.

02.12.2025 06:16 πŸ‘ 4 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Back in Germany and looking at a full day of teaching.

At least it is Winter wonderland here.

24.11.2025 07:09 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Final day of my trip to Australia and finishing with a bang:

AusTRiM conference starting of with a session on rare diseases.

19.11.2025 22:33 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Post image

Good Morning Melbourne.

Lovely debate at the ACTA symposium yesterday on "Is AI Driving Smarter, Faster, Fairer Clinical Trials".

18.11.2025 21:10 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Post image

Had a great day yesterday talking at ACTA about Evaluating AI algorithms for healthcare.

17.11.2025 21:37 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Post image

A great couple of days at the University of Queensland.

Never thought I'd take a ferry to work.

15.11.2025 11:40 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Post image

A wonderful day @UQ. Looking forward to continuing discussions around trials for chronic pain.

11.11.2025 22:47 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
Stoppt den Kahlschlag im Wiener Sucht- und Drogenhilfenetzwerk - SDHN Sucht ist eine Erkrankung, die viele Personen in Γ–sterreich betrifft.    Eine KΓΌrzung der Angebote fΓΌr Suchterkrankte betrifft damit uns alle, β€’ als Betroffene oder als AngehΓΆrige β€’ als Steu...

Unglaublich was gerade in Wien abgeht. Die KΓΌrzungen betreffen nicht nur die BeschΓ€ftigten, sondern gehen uns alle an. Bitte unterstΓΌtzt die Petition:

mein.aufstehn.at/petitions/st...

05.11.2025 21:09 πŸ‘ 21 πŸ” 9 πŸ’¬ 1 πŸ“Œ 1
Preview
Incorporating historic information to further improve power when conducting Bayesian information borrowing in basket trials ABSTRACT. In basket trials a single therapeutic treatment is tested on several patient populations simultaneously, each of which forming a basket, where pa

Incorporating historic information to further improve power when conducting Bayesian information borrowing in basket trials

academic.oup.com/biostatistic...

23.06.2025 14:25 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
Design of platform trials with a change in the control treatment arm ABSTRACT. Platform trials are an efficient way of testing multiple treatments. We consider platform trials where, if a treatment is found to be superior to

Design of platform trials with a change in the control treatment arm

academic.oup.com/biometrics/a...

23.06.2025 14:24 πŸ‘ 2 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
Photo of speakers from day 1, all smiling and looking at camera.

Photo of speakers from day 1, all smiling and looking at camera.

Photo of speaker, Christina Yap, giving talk.

Photo of speaker, Christina Yap, giving talk.

Photo of speakers of day 2, all smiling and looking at camera.

Photo of speakers of day 2, all smiling and looking at camera.

Photo of Pavel Mozgunov delivering talk.

Photo of Pavel Mozgunov delivering talk.

Fantastic two days of stimulating talks and discussions at our Workshop on Adaptive and Bayesian Designs in Real Trials, where statisticians, clinicians and patients have shared their experiences of #ClinicalTrials.

Thanks to all our speakers and all those who attended.

06.06.2025 15:29 πŸ‘ 1 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0

A thought provoking event. Glad I could participate.

25.04.2025 05:41 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Photo of Stef Baas giving talk, with presentation screen behind him.

Photo of Stef Baas giving talk, with presentation screen behind him.

Photo of Gianmarco Caruso giving talk, with presentation screen behind him.

Photo of Gianmarco Caruso giving talk, with presentation screen behind him.

Photo of James Willard giving talk, with presentation screen behind him.

Photo of James Willard giving talk, with presentation screen behind him.

(1/2) Another action packed day at the workshop on Adaptive Designs and Multiple Testing Procedures in Regensburg, with great talks from BSU researchers and PhD students - Gianmarco Caruso, Stef Baas and James Willard.

27.02.2025 13:50 πŸ‘ 2 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
Photo of Connor Fitchett giving a presentation with projector screen of slide behind them.

Photo of Connor Fitchett giving a presentation with projector screen of slide behind them.

Photo of Weishi Chen giving a presentation with projector screen of slide behind them.

Photo of Weishi Chen giving a presentation with projector screen of slide behind them.

David Robertson and Thomas Jaki are organising a workshop on Adaptive Designs and Multiple Testing Procedures, happening today and tomorrow in Regensburg.

admtp.github.io/ADMTP2025/

BSU PhD students, Connor Fitchett and Weishi Chen, have presented today.

26.02.2025 15:14 πŸ‘ 2 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
PhD Opportunities | MRC Biostatistics Unit shutterstock_337964138_students_small.jpg We actively support equality, diversity and inclusion and encourage applications from all sections of society. We are committed to widening participation in ...

The deadline to apply for a @mrc-bsu.bsky.social PhD studentship has been EXTENDED to March 27, 2025! πŸ—“οΈβœ¨

Explore the exciting PhD projects available here: www.mrc-bsu.cam.ac.uk/phd-opportun... πŸ”πŸ“š

🌟 Special shoutout to the project by @thomasjaki.bsky.social and myself πŸ‘Ό

17.02.2025 08:24 πŸ‘ 3 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
Post image

I suspect many of us need to hear this today. @charliemackesy1.bsky.social

15.02.2025 20:04 πŸ‘ 57 πŸ” 7 πŸ’¬ 2 πŸ“Œ 1
Preview
Einfache Testverfahren zur ÜberprΓΌfung der Aussagekraft von Bioresonanz-basierten medizinischen Befunden β€” der LeberkΓ€se-Test - Allergo Journal Allergo Journal - Trotz aller AufklΓ€rungsarbeit wird die Bioresonanz weiter benutzt. Seit einigen Jahren sind modifizierte GerΓ€te auf dem Markt, die auch in ReformhΓ€usern zum Einsatz...

Bioresonanz. Die Γ„lteren von euch erinnern sich ja daran, dass ich diese Studie so mag.

link.springer.com/article/10.1...

Warum ist diese Studie so toll?

Weil keine andere Studie Bioresonanz an Menschen, LeberkΓ€se(!), einem feuchten Tuch sowie einem Leichnam(!) ausprobiert hat.

Ein paar Zitate:

02.12.2024 20:20 πŸ‘ 548 πŸ” 190 πŸ’¬ 43 πŸ“Œ 19
Preview
Designs for sequences of early phase (modular) studies at University of Cambridge on FindAPhD.com PhD Project - Designs for sequences of early phase (modular) studies at University of Cambridge, listed on FindAPhD.com

I am looking for a PhD student in Medical Statistics. This project aims to develop new methods for design of early phase trials starting from monotherapy and progressing into combinations. More details are in the link. Feel free to contact me if any questions. www.findaphd.com/phds/project...

26.11.2024 11:53 πŸ‘ 6 πŸ” 6 πŸ’¬ 0 πŸ“Œ 0

Interested in learning about Bayesian Clinical Trials? We are running a 2-day short course (24th-25th February 2025) on the topic directly prior to the Adaptive Designs and Multiple Testing Procedures Workshop.

To register and more information visit admtp.github.io/ADMTP2025/co...

25.11.2024 18:35 πŸ‘ 4 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Statistical Analysis with Missing Data Using Multiple Imputation | LSHTM

Our 3 day short course @lshtm.bsky.social on multiple imputation for missing data using R is now open for registration. 17-19 June 2025. This year the course will be online only. More info here: www.lshtm.ac.uk/study/course...

21.11.2024 07:41 πŸ‘ 7 πŸ” 6 πŸ’¬ 0 πŸ“Œ 1
Preview
A seamless Phase I/II platform design with a time-to-event efficacy endpoint for potential COVID-19 therapies - Thomas Jaki, Helen Barnett, Andrew Titman, Pavel Mozgunov, 2024 In the search for effective treatments for COVID-19, the initial emphasis has been on re-purposed treatments. To maximize the chances of finding successful trea...

Our design for the early phase platform AGILE for treatments for COVID-19 has just been published.

journals.sagepub.com/doi/10.1177/...

19.11.2024 11:54 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
Confidence intervals for adaptive trial designs II: Case study and practical guidance In adaptive clinical trials, the conventional confidence interval (CI) for a treatment effect is prone to undesirable properties such as undercoverage and potential inconsistency with the final hypoth...

Our part 2 series paper in peer review...

Confidence intervals for adaptive trial designs II: Case study and practical guidance

arxiv.org/abs/2411.08771

14.11.2024 21:18 πŸ‘ 8 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0
Preview
Confidence intervals for adaptive trial designs I: A methodological review Regulatory guidance notes the need for caution in the interpretation of confidence intervals (CIs) constructed during and after an adaptive clinical trial. Conventional CIs of the treatment effects ar...

Our part 1 series paper in peer review ...

Confidence intervals for adaptive trial designs I: A methodological review

arxiv.org/abs/2411.08495

14.11.2024 21:19 πŸ‘ 5 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
Post image

Registration is open for the next Adaptive Designs and Multiple Testing Procedures Workshop (taking place on 26th-27th February 2025Β in Regensburg, Germany). For further details and to register, please seeΒ admtp.github.io/ADMTP2025/regi…

25.10.2024 19:45 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0