MRC CoRE in Exposome Immunology

This International Women’s Day we are celebrating the leadership of Professors Judi Allen and Fiona Powrie, the Directors of the MRC Centre of Research Excellence in Exposome Immunology. Professor… | ... This International Women’s Day we are celebrating the leadership of Professors Judi Allen and Fiona Powrie, the Directors of the MRC Centre of Research Excellence in Exposome Immunology. Professor Jud...

For International Women’s Day, we celebrate Professors Judi Allen and Fiona Powrie, leaders of the MRC CoRE in Exposome Immunology. Allen explores immune responses to parasites, while Powrie uncovers how immunity shapes gut balance and inflammation.

Find out more: www.linkedin.com/feed/update/...

We had a great time at the annual Kennedy Network Conference in Birmingham last week! We really enjoyed the chance to listen to some excellent keynote talks, present some of our own work, and hear what the wider network is up to! Looking forward to next year already🌸🌼
@kiroxford.bsky.social

Looking to build vital skills for your future? Additional training or workshops could give you an important edge!

Our Career Enhancing Grant supports training like this. Applications close 25 March.

Explore how we can support you & apply here: https://bit.ly/3QedNDL

This #February11 we are celebrating Prof Jessica Teeling, winner of the BSI Public Engagement Award! Her grant‑supported “Snakes and Letters for a Healthy Brain” project is inspiring conversations on dementia risk + immunity. #WomenInScience

Read here: https://bit.ly/3Ktiito

Marking #February11 by celebrating Professor Tracy Hussell, BSI President, and her Nature Mentoring Award for Lifetime Achievement.

A great recognition of her commitment to supporting early career researchers and strengthening the immunology community.

#WomenInScience #Immunology

Professor Tracy Hussell Receives Nature Lifetime Achievement Award for Mentoring in Science Professor Tracy Hussell receives the 2025 Nature Lifetime Achievement Award for Mentoring in Science, recognising her outstanding support of early-career researchers.

🏆 Huge congratulations to our Director Professor Tracy Hussell @tracyh9494.bsky.social who has been awarded the Nature 2025 Lifetime Achievement Award for Mentoring in Science for her exceptional support of emerging scientists.

#ImmunoSky @nature.com

sites.manchester.ac.uk/lydia-becker...

🔈It's BSI Congress time and we're thrilled that this year's keynote speaker is the Becker's Immuno-matrix Branch Lead and @exposomeimmunology.bsky.social Director @profjudiallen.bsky.social !

#BSI25 #BeckerAtTheBSI #ImmunoSky

Airway macrophage specific expression of a dense glycocalyx and its remodelling following viral infection The glycocalyx is best studied for its regulation of immune cell trafficking from the vasculature into inflamed tissues. The glycocalyx is composed of a range of glycans and glyco-proteins that form a...

Delighted to share our new pre-print from PhD student Ziyun Zhang joint with @tracyh9494.bsky.social demonstrating that lung alveolar macrophages have a dense glycocalyx and interstitial macrophages do not, @mcrcellmatrix.bsky.social @lydiabeckeriii.bsky.social www.biorxiv.org/content/10.1...

The role of ecoimmunology in tackling the emerging threats of climate change and the exposome Nature Immunology - Climate change creates a multitude of challenges over the human life-course, influencing our exposomes and shaping immune function — requiring researchers to consider...

so excited to share our article in @nature.com Immunology on the many challenges of climate change has for our immune function, infection susceptibility and disease and the need for new ways to research this. Will do a thread later! 🧪 @lydiabeckeriii.bsky.social @exposomeimmunology.bsky.social

Huge congratulations to @sheencr.bsky.social and colleagues at the Ardwick Climate Action Group on their Health Creation Alliance award for “Best health creation approach to seeking and using community insight”, sponsored by AHRC/UKRI.

bit.ly/4opP11w

#SciCom #Pollution #HealthPolicy

Designing bunting

Preparing bunting

Counting cars

Great to work with budding young scientists as they designed experiments to investigate air pollution! @exposomeimmunology.bsky.social @lydiabeckeriii.bsky.social @fbmh-uom.bsky.social

A great afternoon celebrating the award of our MRC CoRE in person. We heard about projects spanning our discovery pipeline, from ExWAS and mechanistic barrier immunology, to potential therapeutic angles for IBD and machine learning for diagnostics.

#exposome #immunology

(MRC DTP) Immune microbiome cross talk and skin inflammation in cutaneous Crohn’s disease at The University of Manchester on FindAPhD.com PhD Project - (MRC DTP) Immune microbiome cross talk and skin inflammation in cutaneous Crohn’s disease at The University of Manchester, listed on FindAPhD.com

Excited to share this MRC DTP PhD opportunity with our lab, Kevin Couper and Kat Koyte to explore immune microbial cross talk in cutaneous Crohns’s disease. Info here: 🧪

Our single cell & spatial omics #bioinformatics course starts on Monday! 📚

You’ll get live training on Zoom & access to self-paced materials to help you keep up with the latest in single cell and spatial methods.

Don't forget, BSI members get 50% off! bit.ly/4emxfIt

(MCR DTP) Macrophage clearance of hyaluronan: mechanisms and consequences for lung disease at The University of Manchester on FindAPhD.com PhD Project - (MCR DTP) Macrophage clearance of hyaluronan: mechanisms and consequences for lung disease at The University of Manchester, listed on FindAPhD.com

📣 PhD project available 📣
Interested in immuno-matrix interactions and matrix regulation?
This project will investigate how hyaluronan is cleared from the lungs after infection. 🫁
@profjudiallen.bsky.social
@lydiabeckeriii.bsky.social @mcrcellmatrix.bsky.social

www.findaphd.com/phds/project...

📣 #BSI25 programme update

We are sorry to announce that Prof. Yasmine Belkaid will no longer be able to join us at BSI Congress this year. We are, however, delighted to announce our new keynote speaker: Prof. Judi Allen from @manchester.ac.uk!

Find out more here: https://bit.ly/4nm9QKt

Nobel prize awarded for discovery of immune system’s ‘security guards’ The discovery of cells that prevent the immune system from hurting the body is paving the way for new treatments for autoimmune diseases and cancer.

This year's Nobel Prize in Medicine honors the discovery of regulatory T cells (T-regs).

In this piece, our Director Prof Tracy Hussell @tracyh9494.bsky.social explains how the recipients discovered T-regs - transforming autoimmune disease research.

#ImmunoSky

theconversation.com/nobel-prize-...

🌟 Postdoc Opportunity – MRC CoRE in Exposome Immunology 🌟
Join us to explore how the exposome shapes complex disease risk using multi-omics & global biobank data. @kiroxford.bsky.social , @exposomeimmunology.bsky.social

✅ Apply: lnkd.in/gJHJDvKn

🗓️ Deadline: 12pm, 30 Oct 2025

Allergen-induced airway matrix remodeling in mice can be prevented or reversed by targeting chitinase-like proteins Allergic airway matrix remodeling occurs independently of IL-13 and IL-17A and is driven instead by chitinase-like proteins.

Allergen-induced airway matrix remodeling in mice can be prevented or reversed by targeting chitinase-like proteins | Science Immunology www.science.org/doi/10.1126/... 🎉🎉
@hetompkins.bsky.social @drtesutherland.bsky.social @mattoburgess.bsky.social @james-ep.bsky.social
@profjudiallen.bsky.social

Intestinal challenges shape the polarisation of protective dural memory CD4 T cells The meninges house several innate and adaptive immune cell populations[1][1]–[3][2]. These predominantly localise within the dura mater and include gut-derived IgA-secreting plasma cells[4][3]. Whethe...

New paper alert! 🎉 Check it out here: biorxiv.org/content/10.1... Here we show that intestinal bacterial, helminth and fungal challenges polarise CD4 T cell populations in the dural meninges.

We have a new Postdoc position advertised as part of our recent long-term Wellcome funding to join an established Postdoc and technician. I’m so excited to explore the role of the glycocalyx in CNS-inflammation. So many tools and expertise to work with! www.jobs.manchester.ac.uk/Job/JobDetai...

Standing room only for the entertaining and touching inaugural lectures of Prof Matt Hepworth and Prof Cath Lawrence today, featuring surprise cameos from Rasputin, an angry goose, and a fondly remembered comic book character.

Congratulations! 🥳

FindAPhD : MRC CoRE in Exposome Immunology at The University of Manchester Apply for a PhD: MRC CoRE in Exposome Immunology at The University of Manchester

🎓 6x fully-funded 4-year PhD studentships 🎓

We are recruiting our first cohort of PhD students to start Oct 2026.

Students will shape their own projects within supervisory teams spanning the universities of Manchester & Oxford.

www.findaphd.com/phds/program/mrc-core-in-exposome-immunology/?p6899

WE ARE HIRING! www.manchester.ac.uk/exposome-jobs

Vacancies inc. 3x PDRA positions, 2x data scientists and a Transition Fellowship in Air Pollution.

Join us as we embark on a 14 year journey to understand how the exposome impacts immune regulation and chronic inflammation.

#hiring #immunosky