How do biomolecular condensates🫧 interact with membranes? We show that dielectric permittivity contrast between coexisting phases directly governs condensate wetting behavior.
👉 preprint: bit.ly/4qBmVRx
Permittivity matters.🧪🫧
It was my pleasure to present at the SAIB Lipids Symposium for the first time. I had very enriching discussions about the role of membranes and condensates in cell biology!
1/3 📢 New work from our lab 📢 We uncover a unifying dielectric principle for biomolecular condensates! 💦Contrary to intuition, we find that it is not a condensate’s absolute polarity, but the permittivity contrast with its surroundings, that governs its affinity for membranes. #GUV #condensates
Join the Membrane Structure and Function Subgroup will be hosting a webinar on Tuesday, March 25 at 11:00 AM ET. The presentations will explore recent breakthroughs, foundational concepts, and future directions in membrane biophysics.
Register here: buff.ly/YOAPVID
1/8 Exciting new work with Agu @mangiarotti.bsky.social @mpici.bsky.social ! 🚀 Our latest study explores how lipid packing and cholesterol regulate the interaction of biomolecular condensates with membranes. It turns out, it’s not just about membrane phase. Packing is the key! 🧵👇
rdcu.be/eelLq
