RESEARCH PAPER: Combinatorial use of VHL and KEAP1 PROTACs reveals unexpected synergy and hook effect relief
By Islam et al., and Luca Busino
➡️ https://genesdev.cshlp.org/content/40/5-6/308.abstract
Penn Medicine
#PROTAC #KRAS #cancer #cancertherapy
A blue and green hummingbird in flight. The bird's body is in sharp focus but its wings are blurred. Text says photography competition 2026, theme colours of nature, open to entries from RSB members aged 19 years and over, @royalsocbio, www.rsb.org.uk/photocomp, closes 5 May 2026
Close up of a marine organism with colours including bright red, orange and white. The organism is camouflaged in the centre. Text says young photographer of the year competition 2026, theme colours of nature, open to anyone aged 18 years old or under, @royalsocbio, www.rsb.org.uk/photocomp, closes 5 may 2026
We're pleased to announce that our photography competition is now open! This year, we're inviting people to submit photos that sum up the theme of 'colours of nature.'
📆 The deadline is 5 May 2026 so get outside and start snapping!
Find out more: www.rsb.org.uk/photo-compet...
#BritishScienceWeek
One week left to register and submit your abstract for the UK C. elegans meeting. Southampton, April 15th-17th. @gensocuk.bsky.social
genetics.org.uk/events/uk-c-...
Love seeing feral pigeon variation...surely the most extensive of any wild bird! How amazing that they thrive in the concrete jungle. Here are some examples from across the UK, being studied for projects supported by @gensocuk.bsky.social @leverhulme.ac.uk @britishecologicalsociety.org
New Heredity Podcast! 🎙️ 📻 🔊
In the second episode from @popgroup2026.bsky.social in Lille, plenary speakers @clairemerot.bsky.social & Denis Roze tell us about their talks and their experience at the conference.
👂 Listen here: shows.acast.com/heredity-pod...
@gensocuk.bsky.social
Close up of electrophoresis technique. Text says RSB training, Forensic DNA profiling in crime scene & paternity testing, 18-19 May 2026, 11:00-14:00, online
We're pleased to announce that our Forensic DNA Profiling in Crime Scene and Paternity Testing training course will be taking place this May!
📆 18-19 May 2026, 11:00 to 14:00 each day, online
Find out more and book your place: my.rsb.org.uk/item.php?eve...
#ForensicDNA #PaternityTesting
OUTLOOK: Flicking the switch for B cell development
By Ashley Ng and Stephen Nutt
➡️ https://genesdev.cshlp.org/content/40/3-4/143.full
Also read:
➡️ https://genesdev.cshlp.org/content/40/3-4/233.full
WEHI (The Walter and Eliza Hall Institute of Medical Research) University of Melbourne
#Bcell
The deadline to apply for our Communicating Your Science workshop (15–17 April) is this Sunday! Don’t miss your chance to sharpen your science communication skills & apply now:
genetics.org.uk/grants/comm-...
![Cover image ‘Female leopard in the Cederberg Mountains, Western Cape’, copyright [Cape Leopard Trust], used with kind permission [Jeannine Hayward, Cape Leopard Trust]](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:2zrogycccpn7vl77co3nvtjt/bafkreidkbfjhbuzc5bsi2qzxpb7fmyeucmvvb5vn5c7mz26ylecy4hb5ay)
Cover image ‘Female leopard in the Cederberg Mountains, Western Cape’, copyright [Cape Leopard Trust], used with kind permission [Jeannine Hayward, Cape Leopard Trust]
February issue out now
www.nature.com/hdy/volumes/...
📸 © Jeannine Hayward, Cape Leopard Trust
@gensocuk.bsky.social
Relaunch of our London Fly Meeting - whole afternoon of amazing science @ucl @lmcb-ucl.bsky.social sponsored by @gensocuk.bsky.social
RESEARCH PAPER: Mutant p53 binds and controls estrogen receptor activity to drive endocrine resistance in ovarian cancer
By Shao et al., and Maureen Murphy
➡️ https://genesdev.cshlp.org/content/40/3-4/199.full
The Wistar Institute
#ovariancancer #p53 #cancertherapy #endocrineresistance
Come celebrate our Anniversary Day in Edinburgh, 25 & 26 June!
Join us for talks from our Honorary Members, Prize & Medal winners, and our Summer Students.
Programme & registration details: genetics.org.uk/events/anniv...
Registrations are now OPEN! Join us in Newcastle for the “RNA in Physiology and Disease” conference, an international meeting bringing together world-leading RNA biologists and emerging researchers.
Early bird deadline: 1 May
Abstract deadline: 30 June
Register now: genetics.org.uk/events/rna-i...
🚨 NEW ISSUE ALERT!!! 🚨
New Outlook, Review, and Research articles online now at Genes & Development.
Click on the link to learn more:
➡️ https://genesdev.cshlp.org/content/40/3-4.toc
Have a look at this fantastic meeting and save the date!
The “RNA in Physiology and Disease” conference, hosted by @gensocuk.bsky.social, will take place 7–9 September 2026 in Newcastle, UK.
genetics.org.uk/events/rna-i...
🎙️🔊📻 New Heredity podcast!
From PopGroup 59 in Lille.
Plenary speaker Florencia Camus talks about:
1. The conference
2. Conflict and coadaptation between the mitochondrial and nuclear genomes
Listen here: shows.acast.com/heredity-pod...
🎙️ G&D Voices: Author Lori Sussel 🎙️
From submission to publication, our authors’ experiences matter.
Here’s what one of our authors had to say about publishing with G&D.
Learn more about publishing with G&D here:
➡️ https://genesdev.cshlp.org
Scientific fluorescence microscopic images. Text says RSB training, introduction to image processing and analysis in ImageJ, 20 April 2026, The University of Warwick
ImageJ is the industry standard for scientific imaging but has a reputation for being difficult to learn - so we're running an Introduction to image processing and analysis in ImageJ training course in April!
📆 20 April, 10:00-16:00, University of Warwick
Learn more: my.rsb.org.uk/item.php?eve...
Impacts of temperature on recombination rate and meiotic success in thermotolerant and cold-tolerant yeast species
@caitismuheil.bsky.social
www.nature.com/articles/s41...
@gensocuk.bsky.social
Pleased to be able to offer a summer placement at the Centre for Neuropsychiatric Genetics and Genomics @cardiffuni.bsky.social through this scheme.
Research Access Placements are open to undergraduates from underrepresented backgrounds
@gensocuk.bsky.social
Pleased to be able to offer a summer placement at the Exeter Centre for Hyperinsulinism Genetics through this scheme. The Research Access Placements programme is open to undergraduates from underrepresented backgrounds
@gensocuk.bsky.social
🆕 ADVANCE ONLINE 🆕
RESEARCH PAPER: B-lineage commitment is dependent on a reversible epigenetic switch
By Tingvall-Gustafsson et al., and Mikael Sigvardsson
➡️ https://genesdev.cshlp.org/content/early/2025/11/20/gad.353002.125.abstract
#hematopoiesis #Bcell #transcriptionfactor #epigenetics
Rapid evolution of a large structural polymorphism during a bacterial epidemic
www.nature.com/articles/s41...
Balancing selection maintains intraspecific diversity in a deep-sea fish
www.nature.com/articles/s41...
Dwarfism in Pinus taeda originates from independent somatic mutations co-localized in a shared genomic region
www.nature.com/articles/s41...
⭐ Check out our January issue ⭐
www.nature.com/hdy/volumes/...
@gensocuk.bsky.social
Glad to receive a PhD prize from the @gensocuk.bsky.social for the work I lead on the origin and diversification of stratified epithelia.
Thanks to @frelab.bsky.social , the lab, and all collaborators involved.
Special thanks to @candice-merle.bsky.social for her help throughout the project.
🆕 ADVANCE ONLINE 🆕
RESEARCH PAPER: Mutant p53 binds and controls estrogen receptor activity to drive endocrine resistance in ovarian cancer
By Shao et al., and Maureen Murphy The Wistar Institute
➡️ https://genesdev.cshlp.org/content/early/2025/11/05/gad.352953.125.abstract
#ovariancancer #p53
Deadline extended! You now have more time to apply for our Communicating Your Science workshop (15–17 April).
Apply today and take your communication skills to the next level: genetics.org.uk/grants/comm-...
Image of two barn owls copyright Quentin Fort. Accompanying the winning paper of the 2025 student paper prize "Too big to purge: persistence of deleterious Mutations in Island populations of the European Barn Owl (Tyto alba)".
Congratulations 🎉
We are pleased to announce the winners of the annual prize for the best student-led paper in Heredity for 2025. The award for this year goes to Eléonore Lavanchy from the University of Lausanne, Switzerland.
➡️ www.nature.com/collections/...
@gensocuk.bsky.social
