Friends! I am so happy to share our new preprint!
Hydrogen peroxide has been the most common reactive chemical threat to life forms since the Great Oxygenation Event 2.5 billion years ago.
How do animals like C. elegans sense it fast and escape?
www.biorxiv.org/content/10.6...
Thread 1/
and the winner of the "2025 best thing on Internet" has just arrived
neal.fun/size-of-life/
@carlbergstrom.com
The funds are approved! We're hiring a postdoc to build a CRISPRa toolkit to identify new aging mechanisms in C. elegans.
Email or DM me to find out more. Please share & repost!
Looking for new, local science podcasts to keep you up to date on research that matters?
Check out the two podcasts from the @whiteheadinstitute.bsky.social: AudioHelicase and BioGenesis!
π§ bit.ly/3J9Yw5p
From our latest episode of #AudioHelicase: four Whitehead Institute researchers gain unique insights into biological processesβfrom regeneration to organ functionβby studying them within the rich context of their natural environment. Listen here: wi.mit.edu/multimedia/a...
βDeveloping this tool required combining diverse skillsets through the sort of ambitious interdisciplinary collaboration thatβs only possible at a place like Whitehead Institute,β @weissmanlab.bsky.social says.
New tool reveals a detailed history of tumor growth: wi.mit.edu/news/mapping...
How do proteins know where to go inside of a cell? Postdoc Henry Kilgore answers our latest #AskaScientist question. Learn how students can submit their own questions: wi.mit.edu/bionook/ask-...
New preprint! We solve a mystery you didn't know existed. Mitotic cells lack new transcription but require ongoing translation. Interphase mRNA half life is only 2-4 hrs. So how do cells arrest in mitosis for hours without depleting their transcriptomes?
www.biorxiv.org/content/10.1...
Two PhD students carrying an image of a drosophila testis down the sidewalk
Two PhD students carrying an image of a drosophila testis across the street
Two PhD students carrying an image of a drosophila testis down the sidewalk
Image of a drosophila testis in a freight elevator
Things you might see in Kendall Square: a giant image of a drosophila testis traveling a mile down the street
We had so much fun at Expedition: Bio, Whitehead Institute's summer science program for middle school students! Here's everyone showing off what they learned at Friday's poster session. π§¬π±π§«
So nice to see another group of middle school students getting into the lab and out into the field as part of the Expedition:Bio summer program.
Just as cancer cells can co-opt other cell types to protect themselves, so can therapies co-opt various cell types to destroy the cancer. Read "The company we keep: Revealing cancerβs accomplices": wi.mit.edu/news/company...
Sometimes itβs great to pause and appreciate the incredible work at #WhiteheadInstitute. Itβs not every day you get to work alongside people pushing the boundaries of #CancerResearch and making real strides in understanding and treating cancer.
#MIT #BiomedicalResearch #Immunology #ResearchSky
Toxoplasma gondii divides by endodyogeny β a process in which two daughters form inside a mother cell, eventually consuming the mother cell. In special cases, as captured in this image, a single cell spawns a multitude of daughters. Credit: Dominic Schwarz. #WhiteheadWonders
60 seconds of mitochondrial biology for lunchtime viewing!
Logo for "Kohn's Zone" podcast
Someone told me what the world needs most is another podcast, & by the time I figured out that person was being facetious, it was too late.
Announcing the launch of "KOHN'S ZONE: Challenging the Conventional Wisdom About Education & Kids" (2 episodes posted; new ones due every 2 weeks): is.gd/JiaK2w
Animals that enter states of dormancy, such as daily torpor or hibernation, live much longer compared to closely related species. But why is that so? And what does it reveal about aging? Whitehead Institute Member SiniΕ‘a Hrvatin shares how his research probes these questions.
Interesting glimpse into Sinisa Hrvatin's work studying hibernation and torpor and how their discoveries can inform our understanding of aging and disease progression.
. @whiteheadinstitute.bsky.social researchers developed Perturb-Multimodal, a powerful new approach that simultaneously measures how genetic changes affect both #GeneExpression and cell structure in intact liver tissue.
π°: bit.ly/440TrVi
π @cellpress.bsky.social: bit.ly/3TEs2ST
Researchers in the Oni lab study how pancreatic cancer cells manipulate their microenvironment to escape immune attack. Read how the Oni lab and others at Whitehead are studying cancer in context: wi.mit.edu/news/company...
This article is part of our series, βBiology in its natural habitat: studying cellular processes in contextβ. View the entire collection here: wi.mit.edu/series/biolo... #WhiteheadStoryArc
Humans don't regrow body parts after an injury, but certain animals can and do. The planarian, a tiny, water-dwelling flatworm, is one such organism. This multipart video explainer explores what we know about planarian regeneration, and what it could mean for human health: wi.mit.edu/news/how-neo...
A researcher can learn a lot from studying a single gene or cell type in isolation. But study a component within the context of its environment, and the picture becomes even more clear. Read our latest #WhiteheadStoryArc: wi.mit.edu/series/biolo...
Interesting new collection of stories highlighting the importance of studying biology "in its natural habitat."
New pre-print! Ryan Kim et al distinguish the roles of the Spindle Assembly Checkpoint as a surveillance pathway only triggered by mitotic errors vs a mitotic timer that is required in every cell division.
www.biorxiv.org/content/10.1...
Whitehead Institute and Harvard researchers have developed Perturb-Multi, a powerful new approach that simultaneously measures how genetic changes, such as turning off individual genes, affect both gene expression and cell structure in intact tissue.
Alisa White, a postdoc in the Page lab studying sex differences in the brain, recalls the moment she became interested in foundational research. wi.mit.edu/news/meet-wh... #WhiteheadPostdocProfiles
We've been asking Whitehead Institute scientists to give us their elevator pitch!
In the first installment of #Sciencein60, grad student Xochitl Luna describes her research on microglia, the brain's resident immune cells that play a role in multiple sclerosis (MS). @xochitl-luna.bsky.social
Learn more about the Seminar Series for High School Teachers: wi.mit.edu/program/semi...
Thanks to all of the high school teachers that come to Whitehead Institute each month for this program so they can take the excitement of biomedical research back to their students.
