Bengt Gless

Bacteria from cows show promising results in treating MRSA infections New research from the University of Copenhagen shows that signaling molecules from a specific Staphylococcus bacterium can treat MRSA infections as effectively as antibiotics.

Check out the write-up of our new publication in #mBio, where we profiled a large number auto-inducing peptide (AIP) signaling molecules from staphylococci.
@ucph.bsky.social @bgless.bsky.social @benjaminsb.bsky.social

news.ku.dk/all_news/202...

#chemsky

Staphylococcal QS mapping, Olsen Lab, UCPH, 2025

I am extremely happy to share this new @biorxivpreprint.bsky.social, which after a long wait updates our previous preprint.
Thanks to main drivers @bgless.bsky.social and @benjaminsb.bsky.social as well as all involved colleagues and collaborators!

www.biorxiv.org/content/10.1...

Peptide Backbone Cleavage and Transamidation via Thioester-to-Imide Acyl Transfer Cysteine thioesters are involved in a myriad of central biological transformations due to their unique reactivity. Despite their well-studied properties, we discovered an unexpected transamidation rea...

I'm excited to share our latest paper reporting an interesting thioester-to-imide acyl transfer reaction of S-acylcysteine.

It was great working with @sabrinaschmied.bsky.social and @christianaolsen.bsky.social

#chemsky #chembio

pubs.acs.org/doi/10.1021/...

#ChemSky

Peptide Backbone Cleavage and trans-Amidation via Thioester-to-Imide Acyl Transfer Cysteine thioesters are involved in a myriad of cen-tral biological transformations because of their unique reactivity. Despite their well-studied proper-ties, we discovered an unexpected trans-amidat...

In a new preprint @chemrxiv.bsky.social, work from @bgless.bsky.social and Sabrina Schmied investigate the mechanism of a rearrangement that can lead to peptide/protein backbone cleavage.

Thanks to #LEOFondet for funding the project that led to this discovery.

chemrxiv.org/engage/chemr...