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Alan Grossfield

@agrossfield

Expert in biomolecular simulation and biophysics. http://membrane.urmc.rochester.edu/ http://grossfieldlab.github.io/loos/ https://orcid.org/0000-0002-5877-2789

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Latest posts by Alan Grossfield @agrossfield

One other thing: the cost for rush processing looks like a lot (comparable to the cost of a poster), but it’s per order, not per poster, so you can amortize it effectively if your whole group orders together.

09.03.2026 20:01 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

I second this. We’ve been using them for a few years, and while their website isn’t wonderful, they’re quick, inexpensive, and the posters look really good.

09.03.2026 20:00 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
Preview
a cartoon says hey everybody an old man 's talking while bart simpson looks on ALT: a cartoon says hey everybody an old man 's talking while bart simpson looks on

A short Bluetorial on plots of NIH application success rates as a function of percentile.

1/20

09.03.2026 14:56 πŸ‘ 112 πŸ” 52 πŸ’¬ 1 πŸ“Œ 4
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Just read the abstract 🫠 via Alexander Magazinov. I don't believe he is on Bluesky.

09.03.2026 11:00 πŸ‘ 119 πŸ” 25 πŸ’¬ 14 πŸ“Œ 50

It’s the HP lattice model of folding that Ken Dill used a lot in the 80s and 90s. It’s so established, there’s no need to have the amino acids. Plus, I just looked at the corrected figure, and there’s *still* a mistake in a different of the same figure β€” they show a chain with a branch.

06.03.2026 22:06 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

I’m wondering why this would ever be a figure anyway? I mean, why would you need the amino acid structures as a paper figure, given they can be found trivially in dozens (hundreds) of places online?

06.03.2026 17:43 πŸ‘ 3 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Me too. I love the Fionavar tapestry (and the sly references to it in other books).

Also, I just finished Under Heaven a few hours ago.

04.03.2026 01:06 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Cell Press has their own version of this, where you can submit to multiple journals simultaneously. It sort-of works β€” because I don’t pick the reviewers or know their identifies, I don’t know how much to trust their reviews and end up needing to essentially re-review the paper myself.

27.02.2026 17:48 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Got it β€” thanks!

26.02.2026 22:13 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 1

I’m confused by the percentages in that graphic, since there are non-overlapping categories (e.g. no one writes a paper in endnote or zotero, though I suppose you *could* write a paper directly on github). What was the prompt that led to that data?

26.02.2026 19:13 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
8 people at a long table covered with Chinese dumplings

8 people at a long table covered with Chinese dumplings

Rochester reunion dinner at #bps2026. Some current lab members, former Mathews lab members, and lab friends. Dumplings and science talk for the win!

25.02.2026 02:59 πŸ‘ 12 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

Neitherβ€” we think they modulate trafficking of the active gpcr by beta arrestins. As far as we can tell, they don’t bind to the gpcr at all.

25.02.2026 00:16 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Dammit, you’re right

24.02.2026 21:46 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 1

Emily just gave an excellent talk on the same work. #bps2026

24.02.2026 20:11 πŸ‘ 10 πŸ” 1 πŸ’¬ 2 πŸ“Œ 0

My former student Dr. Emily Weed-Nichols is presenting her poster on computationally characterizing new compounds to treat opioid overdose today. Come check it out at B45!

#bps2026

22.02.2026 16:24 πŸ‘ 10 πŸ” 2 πŸ’¬ 1 πŸ“Œ 2
A scientific poster describing loos, a suite of tools for analyzing molecular simulations

A scientific poster describing loos, a suite of tools for analyzing molecular simulations

If you’re interested in developing new methods to analyze molecular simulations, come see my poster today at B400. οΏΌ

#bps2026

24.02.2026 16:08 πŸ‘ 9 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
a man presenting a poster with a blue banner to a woman

a man presenting a poster with a blue banner to a woman

My student @aksharasharma.bsky.social is presenting his work on pKa shifts in ionizable lipids at B192
#bps2026

23.02.2026 21:51 πŸ‘ 10 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Jeremy’s talk was fantastic, but depressing. Sadly, it was more consistent with his blue sky feed then his scientific output. If you don’t follow him here (@jeremymberg)οΏΌ, you should.

22.02.2026 19:45 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Waiting to hear @jeremymberg.bsky.social speak at #bps2026 about how to convey the value of biophysics to the public. I think the last time I heard Jeremy give a scientific presentation was when I was a graduate student and he taught NMR and FFTs.

22.02.2026 18:46 πŸ‘ 27 πŸ” 3 πŸ’¬ 1 πŸ“Œ 0

If you’re at #bps2026, keep an eye out for editorial board members wearing β€œtell me about your poster” buttons. We can advise you about submitting your work to Biophysical Journal @biophysj.bsky.social and we can discount the publication fees.

22.02.2026 16:58 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Oops, forgot to tag @emilyweednichols.bsky.social

22.02.2026 16:32 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

I’m sure I’ll run into you at some point! #bps2026

22.02.2026 16:29 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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#CPOW sponsored PI to PI mixer today at #BPS2026 @biophysicalsoc.bsky.social

22.02.2026 16:06 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

My former student Dr. Emily Weed-Nichols is presenting her poster on computationally characterizing new compounds to treat opioid overdose today. Come check it out at B45!

#bps2026

22.02.2026 16:24 πŸ‘ 10 πŸ” 2 πŸ’¬ 1 πŸ“Œ 2

Ironically, Rochester is only expecting 3-4”.

21.02.2026 17:36 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

My parents in Westchester said they were expecting about 15”.

21.02.2026 17:20 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

That’s what my institution has done. It’s got its own issues β€” smaller graduate programs are arguably below critical mass now β€” but at least we’re not betraying the students we admit.

21.02.2026 15:30 πŸ‘ 3 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Also, that sounds more like a qualifying exam thing. At least in my experience, PhD defenses are almost entirely focused on what you did and where you see the work going in the future.

20.02.2026 14:53 πŸ‘ 3 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Thanks for sharing! I think that was from before I started consistently reading your work.

20.02.2026 14:51 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0