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Schafer Lab

@schaferlab

Neuropeptide/GPCR signalling | Ion Channels | "wireless" connectome | Caenorhabditis elegans | Octopus vulgaris https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/

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Latest posts by Schafer Lab @schaferlab

Schafer lab PhD student Joe Gehler-Rahman led a hands-on activity at this year’s @cambridgefestival.bsky.social. You can read all about it here

11.04.2025 23:24 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Congrats to @anna-neuro.bsky.social on a fantastic performance in the Cambridge FameLab final @cambridgefestival.bsky.social, talking about her masters work

11.04.2025 23:19 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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C. elegans wired and wireless connectome: insights into principles of nervous system structure and function - Journal of Biosciences Caenorhabditis elegans is one of the primary model organisms for neuroscience research due to its well-annotated and compact nervous system. Being the first organism with a mapped connectome, publishe...

Latest joint venture from the Schafer and Beets labs
link.springer.com/article/10.1...

11.04.2025 23:11 πŸ‘ 18 πŸ” 6 πŸ’¬ 1 πŸ“Œ 0
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DeorphaNN: Virtual screening of GPCR peptide agonists using AlphaFold-predicted active state complexes and deep learning embeddings G protein-coupled receptors (GPCRs) are important cell surface receptors involved in numerous physiological processes. Although peptides are the cognate ligands for many of these receptors, identifyin...

The latest from Schafer lab: @lariferg.bsky.social, collaborating with Beets lab, uses Alphafold multimer and deep learning to predict GPCR peptide ligands www.biorxiv.org/content/10.1...

21.03.2025 06:43 πŸ‘ 7 πŸ” 4 πŸ’¬ 1 πŸ“Œ 0
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Novel dopaminergic neurotransmission in the Octopus visual system Coleoid cephalopods such as the common octopus have a complex visual system, with a camera-type eye and a large optic lobe, that evolved independently from its counterpart in vertebrates. However, the...

Very excited and proud to finally share this story! πŸ™

We discovered surprising roles for dopamine and acetylcholine in the Octopus visual system…
doi.org/10.1101/2025...

04.04.2025 17:03 πŸ‘ 51 πŸ” 17 πŸ’¬ 1 πŸ“Œ 4