Montse Grifé

Engineering the T6SS of Pseudomonas for targeted delivery of antibacterial and antifungal effectors - Journal of Biological Engineering Background Bacteria employ diverse molecular systems, such as the type VI secretion system (T6SS) to outcompete other microorganisms and adapt to ecological niches. The T6SS is a versatile nanomachine...

Happy to share our paper from a new research line led by @camolsan.bsky.social, where we engineered the T6SS of Pseudomonas putida to deliver effectors against bacterial competitors and fungal pathogens like Botrytis cinerea. @ihsmumacsic.bsky.social

jbioleng.biomedcentral.com/articles/10....

The offensive role of the Bacillus extracellular matrix in driving metabolite-mediated dialogue and adaptive strategies with pathogenic fungi Bacterial□fungal interactions have traditionally been attributed to secondary metabolites, but the role of the bacterial extracellular matrix (ECM) in shaping these relationships has remained unclear....

Excited to share our latest preprint! A fascinating story of chemical dialogue and microbial warfare: the Bacillus extracellular matrix acts as a key driver in the antagonistic interaction with Botrytis, while the fungus mounts a multi-layered defense.
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www.biorxiv.org/content/10.1...

Really cool #singlecell method published in Science! Multiplexed error-robust fluorescence in situ hybridization (MERFISH) to create an image-based single-cell transcriptomics in bacteria 🦠🧫🔬🧪

Diversification of Lipopeptide Analogues Drives Versatility in Biological Activities Cyclic lipopeptides (CLPs) are potent secondary metabolites with diverse biological functions. Bacillus strains primarily produce CLPs of three key families, namely, iturins, fengycins, and surfactins...

Super happy to share my first article at @diegromero.bsky.social´s lab, about Bacillus cyclic lipopeptides and how the diversification of structural variants production impacts biological activities!!
pubs.acs.org/doi/10.1021/...