An SPFH Protein Couples Membrane Stress to Differentiation in Bacillus subtilis https://www.biorxiv.org/content/10.64898/2026.02.06.704340v1
An SPFH Protein Couples Membrane Stress to Differentiation in Bacillus subtilis https://www.biorxiv.org/content/10.64898/2026.02.06.704340v1
๐Collabator Alert๐
Iโm putting together a project on UTIs and the urogenital microbiome and am looking for a collaborator with solid metagenomic sequencing/analysis experience. If youโd be interested in joining the work, Iโd love to talk
#MicroSky #UTISky
A gift of an article from the inimitable Colin Kleanthous as he says a moving farewell to his laboratory. A brave, unrepentant and scientifically brilliant journey is described - please have a read, friends.
www.jbc.org/article/S002...
E. coli is the leading bacterium causing death from AMR infections worldwide. If you'd like to explore approaches to exploit the DNA damage response as alternative antimicrobial, please apply to the following PhD studentship available in my lab starting October 2026: www.findaphd.com/phds/project...
๐ผJOB OFFER: There is a great opportunity for #PDRAs to join the #KathrynLilley #UniversityofCambridge lab to work on an ancient set of effector proteins IM30 family, that promote membrane integrity. See: www.cam.ac.uk/jobs/researc.... Apply by the 13th Feb
Fabian was quicker :) But yes, we have an open postdoc position in bacterial bioenergetics and membrane biology, using on B. subtilis as the model. Come join us! @cbcb-newcastle.bsky.social is a great place to work, and we are a friendly, international lab. Visa+IHS fees covered. #microsky
It was a pleasure to be an examiner of the latest @henrikstrahl.bsky.social PhD graduate Laura Dobby. Great work and a very nice discussion in her viva. Congratulations Dr Dobby! @cbcb-newcastle.bsky.social
Super proud of you! ๐ฆ
Letโs stare into the far red ๐ฎ. A stunning tour-de-force of high-resolution #CryoEM by Gio, Bill, & company reveals how the machinery of photosynthesis redshifts itself so cyanobacteria can live on far red light, deep in the cracks of rocks or under microbial mats. #PlantScience ๐งช ๐งถ๐งฌ ๐พ ๐ฌ ๐
New preprint out from the team! Masterโs student extraordinaire Julia Bauer stumbled across a Ca transporter needed for endospore maturation in Solibacillus ๐งซ๐ฌ www.biorxiv.org/content/10.1...
Possibly outing myself as the biggest nerd ever here but what a massive day for Ryan Sharpe, Oakville, Ontario, Canada appearing on both US Jeopardy and UK University Challenge!!
Postdoc position available!
This is a 2-year post funded by the Academy of Medical Sciences. You'll be based in the Centre for Bacterial Cell Biology here in Newcastle, using super-resolution microscopy to look at the bacterial cell wall. ๐ฌ๐ฆ
Please re-post ๐
www.jobs.ac.uk/job/DMY885/r...
We are happy to join the science community at BlueSky! #MicroSky
First post of the year to mark my return from maternity leave :) Excited to share the first open PhD position in my group.
Deadline end of February.
Please spread the word. www.findaphd.com/phds/projectdetails.aspx?PJID=181239
Single molecule imaging of RecB in vivo reveals dynamics of DNA Double Strand Break repair in Escherichia coli https://www.biorxiv.org/content/10.1101/2024.12.18.629153v1
This has been an ongoing collaboration with Michaela Wenzelโs group since my PhD days so a huge thank you to everyone involved @alansckoh.bsky.social @henrikstrahl.bsky.social and hopefully this provides some cool results/techniques for upcoming AMR research! (3/3) #microsky
ii) daptomycinโs ability to cluster fluid lipid domains requires cell wall precursor lipids whilst membrane depolarisation does not, and finally, the Bacillus IM30 protein LiaH seems to play an intriguing role in clustering these daptomycin-cell wall precursor lipid complexes. (2/3)
So happy our pre-print on daptomycin mechanism of action is now out! Here, we present three main findings: i) daptomycin does not form large membrane pores in either B. subtilis or S. aureus, (1/3)