Rachael Burke

This looks really cool…. Any of my LBGTQ+ / stats nerds Venn diagram intersect crew fancy helping to organise a rainbowR conference?!

Don’t forget about “irrelevant positives”!

Aargh… this is, like, the most obvious thing to me. And un-evidenced based screening (or screening with proven aggregate harm still being offered) drives me up the wall!

I guess I should remember “screening can be bad” is apparently not intuitive.

What is common knowledge in your field, but shocks outsiders?

It's all just linear models. Statistics is, like, three linear algebra operations in a probability-shaped trenchcoat.

I’m not convinced they are unimportant positives either…. U just thing we have absolutely no idea either way! And that seems a bit rash for TB peeps (not you particularly… but the general vibes) to be pushing ACF until we know. There will be individual harms too.

Yea, agree with all that. But I remain very irritated with all the “excitement” about community based screening DESPITE the fact that there is poor evidence on the individual level benefits and harms of detecting asymp. TB.

But what about “unimportant positives”? I mean, once you have a positive test you are obviously going to treat. But what would have happened to those people who never encountered screening for their (“true”) asymptomatic TB? How many would have reverted anyway and had no harm from their TB?

How did you not know that?! It’s a core ID fact!

Given discussions at I had at #ESCMIDGlobal, it might be useful for new researchers to know how a journal editor screens submissions (obviously this is my approach and so it might differ for others).

I feel seen… and I don’t like it… 🤣

Its right there in the title.

Gelman, Andrew, and Hal Stern. "The difference between “significant” and “not significant” is not itself statistically significant." The American Statistician 60, no. 4 (2006): 328-331.

sites.stat.columbia.edu/gelman/resea...

Trump tariffs: How island of penguins and seals ended up on list - BBC News The remote Heard and McDonald Islands haven't been visited by humans in almost a decade.

One plus side of *gestures* *this* is that I have now learnt about the existence of the Heard islands. They seem extremely cool… thousands of penguins, flowing lava, ecosystem with external inputs. It’s extremely cool! 🐧 🏝️ 🌋 www.bbc.co.uk/news/article...

Well, any group can have individual douche bags in it. I feel like overall the Quakers are extremely awesome (doi: not a Quaker, but family are).

My parents are Quakers I think this is reprehensible from the Met police. To make a pre-decided plan to have a force of 20 police (some with tasers) barge into a place of worship is dreadful behaviour and not something we should tolerate in our society.

I’d quite like to know when to start ART in serum CrAg pos / CSF CrAg negative, relatively asymptomatic people though?

Yea, I think it depends what setting you are in and what you are trying to achieve? Biological betterness? Or less cost to people / easier to implement protocols? If you’ve got individualised care, different patients/scenarios are different. For one-size-fits-most policy I’m not sure it’s priority.

There is also a JIAS systematic review of SaPIT and all the other eight trials of earlier vs later TB kicking around (you may recognise some authors 🤣)…. The trials are a bit of a mixed bag.

I mean… Malawi have been starting ART and TB treatment on the same day (as diagnosis, and each other, without steroids) for a few years now. Seems to be fine for most people.

We’ve just finished a trial of same day vs deferred ART (“ART first” vs “TB results first”) in people with TB symptoms. Results in to IAS! But there was v little IRIS seen.

🏆 The Stephen Lawn Prize acknowledges young researchers conducting promising work focused on reducing the burden of TB and HIV/AIDS in Africa.

The Union is proud to present the award at our World Conference on Lung Health.

📖 Be sure to read @rachaelburke.bsky.social and Aliasgar's profiles.

I love this! And so many GREAT people, looking at the names.

@theunion-tblh.bsky.social
@joylawn.bsky.social
@tb-lshtm.bsky.social
@thelancet.bsky.social

Aww, thank you!! And thank you for your FANTASTIC Stephen Lawn Lecture 2023 on the "know-do" gap. It was brilliant.

Come along everyone to what looks like an amazing TB event on Thursday at 5:30pm at LSHTM.

The Stephen Lawn Memorial Lecture 2025.

Open to all!

This is me! Eeek!

I feel slightly uncomfortable blowing my own trumpet (and pasting such a zoomed in photo on bluesky). But the LSHTM crew said I should try to get the word out about the lecture! @lshtm.bsky.social @petermacp.bsky.social

Rachael Burke: integrating equitable HIV and TB research and care “I think what I've really wanted to do since I was a teenager was work on HIV and TB, and conditions that affected people who were disproportionately poor and vulnerable. And research was a nice way i...

A few months ago, I was honoured to receive the Stephen Lawn prize (with Ali Esmail). The Lancet wrote a profile of me, published today! www.thelancet.com/journals/lan.... I'm v looking forward to being at the Steve Lawn lecture on Thursday, by Dr Tereza Kasaeva. www.lshtm.ac.uk/newsevents/e...

Person: "I know 3 stats things: Anova, regression and t test."

Narrator: he only knew 1 stats thing.

Goodness me you have a lot of grants and projects!!

Um… is, your literal wife getting on a plane from Malawi not a good enough method for you?