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The Rokas Lab at Vanderbilt University

@rokaslab

The Laboratory of Antonis Rokas at Vanderbilt University. Tweets should be interpreted as bookmarks, not as endorsements. All opinions are Antonis'. http://www.rokaslab.org

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Latest posts by The Rokas Lab at Vanderbilt University @rokaslab

Student Research Award <p>The ASN Student Research Awards support research by student members that advances the goals of the society: the conceptual unification of ecology, evolution, and behavior. Each award consists of a ...

Just a few days left to submit the ASN student research award (due March 13th)!!!! This is an AWESOME opportunity for students to get some grant writing experience!!! We LOVE reading your grants and giving feedback!!!!!!!!!!! Apply, Apply, Apply!!!!!!

www.amnat.org/announcement...

03.03.2026 14:38 πŸ‘ 23 πŸ” 33 πŸ’¬ 0 πŸ“Œ 0
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🌟 New at #Fungal26β€”the inaugural Fungal Spore Lecture featuring Matthew C. Fisher (Imperial College London).
Working at the One Health interface, Fisher explores how antifungal use and global trade are reshaping the Fungal Kingdom. Join us for his lecture: buff.ly/oCNlI2l

11.03.2026 13:02 πŸ‘ 4 πŸ” 3 πŸ’¬ 0 πŸ“Œ 1
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Did you know that Evolution Letters now publishes reviews?! Our inaugural one is fantastic! Deep learning is opening new doors for evolutionary genomics, especially for nonmodel organisms with sparse or uncertain genomic data. doi.org/10.1093/evle...

06.03.2026 22:11 πŸ‘ 18 πŸ” 13 πŸ’¬ 0 πŸ“Œ 1
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#Yeast #Genetics Meeting 2026 is in June - Abstract deadline is TODAY! Submit your abstract, attend the meeting this summer in Pacific Grove, CA at #Asilomar Conference Grounds, a 107-acre protected coastal state park located on the Monterey Peninsula. #Yeast26 #YGM2026 genetics-gsa.org/yeast-2026/

05.03.2026 20:03 πŸ‘ 14 πŸ” 7 πŸ’¬ 2 πŸ“Œ 1
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Amy Goldberg, PhD - Join The Goldberg lab is moving to UCLA summer 2025, and recruiting postdocs and graduate students. We are a computational lab with occasional wet lab or field collaborators. We will be located in the Depa...

The Goldberg lab at UCLA is hiring one or more postdocs. Flexible start date.

We develop methods to study population genetics of humans, our primate relatives, and our pathogens.

www.goldberglab.org/join

05.03.2026 21:10 πŸ‘ 25 πŸ” 24 πŸ’¬ 1 πŸ“Œ 0
How can fast-evolving DNA retain a fundamental function in cell division? | Nature In a dividing cell, chromosome pairs are pulled apart thanks to attachment sites called centromeres. Yeast genomes reveal key steps in how centromeres have evolved. In a dividing cell, chromosome pairs are pulled apart thanks to attachment sites called centromeres. Yeast genomes reveal key steps in how centromeres have evolved.

I had fun writing this N&Vs on two fascinating new papers on centromere evolution in yeast. If you’re interested in how centromeres adapt yet stay functional, here’s my take. rdcu.be/e6DD0 @nature.com @gautamdey.bsky.social @gsherloc.bsky.social @helsenjana.bsky.social @maxhaase.bsky.social

03.03.2026 21:41 πŸ‘ 37 πŸ” 15 πŸ’¬ 1 πŸ“Œ 2
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Asperfest Next event Asperfest 22 22nd International Aspergillus Meeting March 2026 Asilomar, California, USA 22nd International Aspergillus Meeting Merrill Hall Monday 16th March 19:00 – 22:00 Poster …

With just two weeks to go until the 33rd Fungal Genetics Conference at Asilomar starts, we're happy to reveal the programme for Asperfest, running 16th-17th March:

aspgrpc.com/asperfest/

Will we see you at Asperfest and/or FGC?

02.03.2026 15:39 πŸ‘ 4 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
PearTree β€” Phylogenetic Tree Viewer

So I pleased to announce the conceptual spawn of FigTree: PearTree (acronym still to be finalised). If you want to dive right in it is hosted as a web app here: artic-network.github.io/peartree (click the β€œExample...” button for immediate candy and then click every button you can find).

28.02.2026 19:01 πŸ‘ 163 πŸ” 100 πŸ’¬ 5 πŸ“Œ 4
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Private money cannot replace public funding of science Who should pay for American science? In the current political climate, many are looking to the private sector to compensate for cuts in public funding. At the Harvard School of Public Healthβ€”particula...

My latest:

www.science.org/doi/10.1126/...
Next column will address needed guardrails for private funding of science, esp. in light of #Epstein/ #Summers etc.

26.02.2026 20:25 πŸ‘ 128 πŸ” 49 πŸ’¬ 2 πŸ“Œ 2
Kate Snyder with a huge smile while holding two birds

Kate Snyder with a huge smile while holding two birds

Nicole Creanza and Kate Snyder stand in front of a chalkboard smiling while wearing black sweaters

Nicole Creanza and Kate Snyder stand in front of a chalkboard smiling while wearing black sweaters

New this week! Female birds sing β€” and new Vanderbilt research explains how social behavior shapes that evolution. Dr. Kate Snyder analyzed 1,000+ songbird species and found cooperative breeding & female song reinforce each other over evolutionary time. 🐦🎢 Read more >> https://wp.me/pbblkY-116

27.02.2026 14:18 πŸ‘ 9 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
Evolutionary Medicine Summer Institute – Renaissance Computing Institute (RENCI) at UNC Chapel Hill, May 11-15, 2026

Call for applications, pls share!

2026 Evolutionary Medicine Summer Institute (EMSI) advances research in a frontier of evolutionary medicine. They provide training in methods needed to address cutting edge questions in that frontier.

2026 focus: Climate Change and Health

sites.duke.edu/emsi/

27.02.2026 12:05 πŸ‘ 10 πŸ” 12 πŸ’¬ 0 πŸ“Œ 0
A night vision photo of a peccary with text overlaid. "β€œWe have very few examples of tropical species being affected by climate change. These peccaries are just a first attempt to show that mobile organisms, who can choose where to go (most of the time), and find food everywhere, can still be affected by changes in temperature, even if in subtle ways.” -Malu Jorge"

A night vision photo of a peccary with text overlaid. "β€œWe have very few examples of tropical species being affected by climate change. These peccaries are just a first attempt to show that mobile organisms, who can choose where to go (most of the time), and find food everywhere, can still be affected by changes in temperature, even if in subtle ways.” -Malu Jorge"

Malu Jorge and PhD alum Michaela Peterson published cool work looking at the effects of climate change on white-lipped peccaries! Read more >> https://tinyurl.com/mr23kn7j #Science #Evolution

26.02.2026 14:26 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

This is great #stuffthatmatters. Congratulations to Liedewij Laan and @embopress.org for recognizing the importance and brilliance of this work.

22.02.2026 19:24 πŸ‘ 13 πŸ” 3 πŸ’¬ 1 πŸ“Œ 0
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Oligomerization-dependent and synergistic regulation of Cdc42 GTPase cycling by a GEF and a GAP - EMBO Reports Cell polarity is a crucial biological process essential for cell division, directed growth, and motility. In Saccharomyces cerevisiae, polarity establishment centers around the small Rho-type GTPase C...

New paper out in EMBO Reports!
We show that Cdc42 regulation is oligomerization-dependent and that a GEF and a GAP act synergistically: Cdc24 relieves self-inhibition of oligomeric Rga2, enabling robust Cdc42 cycling.
doi.org/10.1038/s44319-026-00695-7
#cellpolarity #Cdc42 #synergy #syntheticbiology

22.02.2026 18:26 πŸ‘ 16 πŸ” 5 πŸ’¬ 1 πŸ“Œ 0
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EMBO Press co-evolves with molecular ecology and evolutionary biology - The EMBO Journal The EMBO Journal - Molecular ecology and evolution are central to understanding how biological systems function, interact, and diversify. A special issue of this journal reflects the growing...

Read how @embopress.org is expanding its focus on molecular ecology and evolution as central underpinnings of functions/interactions/diversification of biological systems – by @yehumoran.bsky.social, @berndpulverer.bsky.social, and our new team of Editorial Advisors
link.springer.com/article/10.1...

18.02.2026 19:47 πŸ‘ 21 πŸ” 12 πŸ’¬ 0 πŸ“Œ 1
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New work from graduate student Owen Hale (Behringer Lab)! The paper, "Elevated rates and biased spectra of mutations in anaerobically cultured lactic acid bacteria," was published in mBio. Hale tracked 3 species of bacteria through >1000 generations in oxygen-free conditions.

20.02.2026 14:04 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Ancient co-option of LTR retrotransposons as yeast centromeres - Nature Evolutionarily related β€˜proto-point’ centromeres providing resolution to the evolutionary origins of point centromeres are identified in yeast, and comparison shows they evolved in an ancestor with re...

Our paper is now out in Nature:

β€œAncient co-option of LTR retrotransposons as yeast centromeres”

www.nature.com/articles/s41...

A short thread on how retrotransposons helped give rise to yeast point centromeres.

1/14

18.02.2026 16:03 πŸ‘ 227 πŸ” 115 πŸ’¬ 8 πŸ“Œ 10
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An integrative chemical and genomic similarity approach linking fungal secondary metabolites and biosynthetic gene clusters Fungi are well known to biosynthesize structurally complex secondary metabolites (SMs) with diverse bioactivities. These fungal SMs are frequently produced by biosynthetic gene clusters (BGCs).…

Read in our latest issue a paper by @rokaslab.bsky.social & co. from @vanderbilt.edu & @uncg.edu describing an integrative chemical & genomic similarity approach to link fungal secondary metabolites & biosynthetic gene clusters #natprod #secmet

Find it in full hereπŸ”½

17.02.2026 15:22 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Abstracts due for the July Evolution and Medicine Conference in Kiel, Germany! Early discounted registration is also open

Dear friends and fans of evolutionary biology & medicine (#EvMed), deadlines for the 2026 meeting in Kiel Germany are coming up. Looks to be excellent!

March 1, 2026: Abstract submission deadline and travel award decisions

April 1, 2026: Abstract decisions

open.substack.com/pub/evmedrev...

17.02.2026 01:40 πŸ‘ 10 πŸ” 7 πŸ’¬ 0 πŸ“Œ 0

My quote of the day

Ignorance more frequently begets confidence than does knowledge: it is those who know little, and not those who know much, who so positively assert that this or that problem will never be solved by science.

Charles Darwin

12.02.2026 11:33 πŸ‘ 84 πŸ” 34 πŸ’¬ 3 πŸ“Œ 1
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Why teach evolution? | National Center for Science Education Biology is the science of life, and it is arguably the most challenging of all the sciences. Not only does biology build upon the principles of chemistry and physics, it also adds new layers of complexity requiring an entirely different form of scientific analysis.

As we count down to #DarwinDay, we're re-visiting some great pieces on why we teach evolution! "Evolution isn't just a story about where we came from. It's an epic at the center of life itself." https://ncse.ngo/why-teach-evolution-1

10.02.2026 17:01 πŸ‘ 7 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0
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Discovery of additional ancient genome duplications in yeasts Whole-genome duplication (WGD) has had profound macroevolutionary impacts on diverse lineages,1,2 preceding adaptive radiations in vertebrates,3,4,5 t…

With the @rokaslab.bsky.social, three novel whole genome duplication (WGD) events were discovered in the Saccharomycotina yeast species in the Dipodascales
clade. Before now, only four WGD events were known in fungi. This work suggests WGD may be underreported.
www.sciencedirect.com/science/arti...

04.02.2026 18:24 πŸ‘ 15 πŸ” 9 πŸ’¬ 0 πŸ“Œ 0
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A bacterial gene acquired by parasitoid wasps contributes to venom secretion against host defence - The EMBO Journal Horizontal gene transfer (HGT) is an important source of gene innovation in prokaryotic and eukaryotic organisms. Several genes acquired by hosts of parasitoid wasps via HGT have been reported to prot...

Excited to share a new piece of work in @embojournal.org

Parasitoid wasps hijack a bacterial gene that governs venoms against host. Coauthors include @rokaslab.bsky.social and others.

Read more from: link.springer.com/article/10.1...

29.01.2026 00:00 πŸ‘ 22 πŸ” 12 πŸ’¬ 0 πŸ“Œ 0
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Discovery of additional ancient genome duplications in yeasts Whole-genome duplication (WGD) has had profound macroevolutionary impacts on diverse lineages,1,2 preceding adaptive radiations in vertebrates,3,4,5 t…

Excited to announce our latest publication in reporting evidence for three (3!) new whole genome duplications (WGDs) in yeasts. Scientists have often wondered why WGD is so rare in fungi, it turns out we may just not have been looking hard enough! πŸ§ͺ πŸ„ 🧬
www.sciencedirect.com/science/arti...

28.01.2026 17:49 πŸ‘ 44 πŸ” 17 πŸ’¬ 1 πŸ“Œ 1

If you participated in a yeast meeting in 2025, reach out to me about publishing your work from that meeting!

27.01.2026 20:04 πŸ‘ 5 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0
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a group of people are standing next to each other in front of a wall . ALT: a group of people are standing next to each other in front of a wall .

How much do growth morphologies in the Saccharomycotina subphylum vary? πŸ€” With the @rokaslab.bsky.social, integrated datasets of 1,051 species were examined to assess filamentation evol. history and variation. ML models predicted morphologies with 70% accuracy.
academic.oup.com/femsyr/advan...

23.01.2026 19:54 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Cover of Evolutionary Studies Magazine Fall 2025 issue featuring a black Darwin's finch with a large beak perched on green succulent vegetation. The magazine title and ESI logo appear in white text at top left. Cover stories listed include 'Kate Snyder: Evolution & Birds', 'The Evolution of Exercise in Horses', and 'The Scopes Monkey Trial Centennial Symposium'.

Cover of Evolutionary Studies Magazine Fall 2025 issue featuring a black Darwin's finch with a large beak perched on green succulent vegetation. The magazine title and ESI logo appear in white text at top left. Cover stories listed include 'Kate Snyder: Evolution & Birds', 'The Evolution of Exercise in Horses', and 'The Scopes Monkey Trial Centennial Symposium'.

πŸŽ‰ Fall 2025 Evolutionary Studies - the Magazine is live!
Horses that ignore genetic stop signs, humans adapting to extreme deserts, the #evolution of birdsong, and our Friend of Darwin award.
Read it: https://loom.ly/cACR5HY
#science

21.01.2026 06:05 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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πŸ“£ #EMBOEvoEco returns in 2026 to uncover the mechanistic foundations of ecological and evolutionary change!

Keynote lectures will spotlight the ecology and evolution of symbiosis.

Submit your abstract for the EMBO Workshop: https://s.embl.org/eae26-01-bl!

13.01.2026 12:26 πŸ‘ 10 πŸ” 6 πŸ’¬ 0 πŸ“Œ 0
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Are you a scientist studying population, evolutionary, or quantitative genetics in Drosophila, mice, mammals, maize, humans, Arabidopsis, Zebrafish, yeast, plants, worms, or other model organisms? πŸͺ°πŸπŸŒ½πŸ‘€πŸŸπŸΊπŸŒ±πŸͺ±

#PEGQ26 is the conference for you! Submit an abstract: buff.ly/ue9xUSY

#PopGen #Evo

15.01.2026 17:04 πŸ‘ 4 πŸ” 4 πŸ’¬ 0 πŸ“Œ 1
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We made a new lager beer! "Indomitus" for wild and untamed. Brewed with a wild yeast strain from Patagonia! This is the result of a super fun collaboration (and lots of hard work) with Francisco Cubillos in Chile (@fcocubillosr.bsky.social) and AndrΓ©s Furukawa at the Nils Oscar Brewery in Sweden.

15.01.2026 13:02 πŸ‘ 41 πŸ” 10 πŸ’¬ 1 πŸ“Œ 1