Hello nephsky. I got my first ever first author publication. Just a case series (it's on roxadustat in PRCA) but it's a huge milestone for me. Give it a read 🙏🏾 onlinelibrary.wiley.com/doi/10.1111/...
This study in #ASNJASN examined the link between preeclampsia during pregnancy and early signs of kidney damage in women. Check out the full article: kidney.pub/JASN1001
Did we (meaning "you" of course, because you voted) get them right? Is there something missing or is the order wrong? #NephJC #TopTenStories2025
Come discuss with an international cadre of nephrologists & other interested parties on 1/6/26 at 9 pm EST on #Twitter
The new @kdigo.org anemia guidelines are out in @kidneyint.bsky.social
www.kidney-international.org/article/S008...
(Somewhat anemic in their support of iron IMO) include sections on HIF-PHIs
Worth a future #nephJC?
This image is from a biopsy of a young female who presented with proteinuria during pregnancy. Routine immunofluorescence was negative. What is this stain and what is your diagnosis?
#DiagnoseThis #nephsky #pathsky #renal #kidneypath
The second sibeprenlimab paper in @nejm.org
(At least we gave it an oral at #KidneyWk unlike the poster for the phase 2 data in 2023!)
www.nejm.org/doi/full/10....
Oral Abstract Session 🌟
▶️ The greater the reduction in Proteinuria, the better the outcomes in IgA Nephropathy! 🔑
▶️ Outcomes across diseases and age in the CureGN cohort! 👏
#KidneyWk #ISGDTweets #GlomerularDisease
A case of fibrillary glomerulopathy showing smudgy mesangial/capillary loop staining for IgG, positive DNAJB9 staining and fibrils on EM. Superimposed on diabetic nephropathy with KW nodules. #renalpath #pathology #renal #pathsky #kidneypath
A case of NELL1 positive membranous nephropathy with global but discontinuous capillary loop staining for IgG (left) and NELL1 (right).
#kidneypath #renal #pathology #pathsky #nephsky
Dual therapy with finerenone + empagliflozin cut albuminuria by ~30% more than either drug alone in CKD + T2D—with no added safety concerns.
A promising step for combo treatment in DKD.
#CKD #T2D #SGLT2i #Finerenone #CONFIDENCE #Nephrology #BlueskyMD
Kidney Transplantation Improves Survival in Antineutrophil Cytoplasmic Antibody–Associated Vasculitides With End-Stage Kidney Disease - Kidney International Reports www.kireports.org/article/S246...
The study assessed the efficacy and safety of BTK inhibitor #zanubrutinib in patients with primary membranous nephropathy. #kidneywk #nephrology #glomerulardisease #nephsky
A NY Times article reported that some are “microdosing” GLP-1s like ozempic, hoping for benefits without side effects.
The experts quoted said we don’t know if it would work.
Umm.
I guess they didn’t read the phase 2 trials!
More below, with some nuance/caveats👇
open.substack.com/pub/insideme...
Can I give a bx 5 diagnoses? You bet I can. ATN with vacuolization + eosinophilic AIN -> contrast nephropathy; marked RBC casts without crescents (pt highly anticoagulated) c/w anticoagulant nephropathy, Amyloidosis, incident IgA (fatty liver disease),+ DN. #renalpath is fun! #pathsky #nephrology
