Maja Köhn

A proteome-wide dependency map of protein interaction motifs - Nature Structural & Molecular Biology Ambjørn and Meeusen et al. functionally characterize all reported and a comprehensive set of predicted short linear motifs (SLiMs) using base-editing screens, identifying 450 reported and 264 predicte...

Happy to see our work on defining a dependency map of short linear motifs out. We use base editing screens to install more than 80000 mutations into SLiMs in more than 4000 proteins to determine their contribution to cell fitness. www.nature.com/articles/s41...

Thanks a lot for the invitation and the shout out! It was a wonderful conference!

Kicking off the last session of the symposium, our keynote speaker @mkoehn.bsky.social from
@unibonn.bsky.social spoke about peptide tools used to dissect phosphatase-substrate interactions. Have a look at the human dephosphorylation database (DEPOD) via the link www.depod.org

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#17GPS

You are interested in immunology and how nucleic acid structures contribute to their function and how this impacts disease development - Rayk Behrendt and myself have open PhD positions for a joint PhD program between Bonn and Osaka.

The Lipid Interactome: an interactive and open access platform for exploring cellular lipid–protein interactions AbstractSummary. Lipid–protein interactions play essential roles in cellular signaling and membrane dynamics, yet their systematic characterization has lon

Our paper on The Lipid Interactome is now published, and the database is open:

lipidinteractome.org

@ohsummi.bsky.social @ohsunews.bsky.social
@nadlerlab.bsky.social @jeremybaskin.bsky.social

Please RT to spread the word.

doi.org/10.1093/bioi...

Editor-in-Chief - Physical Sciences Job Description: Editor-in-Chief - Physical Sciences Location: Remote, GBR Our mission is to unlock human potential. We welcome you for who you are, the background you bring, and we embrace individual...

We are hiring an Editor‑in‑Chief for our in-house chemistry portfolio to lead journals in the wider field of phytochemistry, medicinal chemistry, and natural products.

Please like, share, and apply!

wiley.wd1.myworkdayjobs.com/wiley_career...

⏰ Registration is closing soon!
Join us at the 17th German #Peptide Symposium, 4–6 March 2026 in Essen @unidue.bsky.social.
🎤 The full speaker program is now online, featuring @mbogyo.bsky.social, @mkoehn.bsky.social & more.
🔗 www.uni-due.de/17gps/

#17GPS

Promotional image for a 24-hour online conference on LinkedIn hosted by American Elements and Royal Society of Chemistry, scheduled from March 3, 2026, at 12:00 GMT to March 4, 2026, at 12:00 GMT. Features an orange and black background with abstract geometric designs and the text 'Save the date.'

Looking for something inspiring to kick off your 2026? 🎉 #RSCPoster registration is OPEN!

Join one of the largest online poster events, uniting researchers from every career stage & every corner of the scientific community.

We can’t wait to see what you’ll share ➡️ https://rsc.li/3XGGvzS

#ChemSky

Pervanadate-induced oxidation relieves autoinhibition of the protein tyrosine kinase SRC A widely used tyrosine phosphatase inhibitor also oxidizes and activates the tyrosine kinase SRC.

Pervanadate is more than just a phosphatase inhibitor!

Read our paper just published in #sciencesignaling showing that pervanadate oxidises and activates SRC kinase too.

Link: tinyurl.com/5ype7e2s

Thanks for the 'focus' by: @nshahlab.bsky.social tinyurl.com/54fcjds3

@babrahaminst.bsky.social

#chembio and #bioorganic crowd. Mark your calendars for ESBOC 2026, registration opens soon!

www.esboc.org.uk

⏱️ 27th-30th May 2026
🏰 The beautiful Schlosshotel Pillnitz GmbH in Dresden/Germany

Hard to believe, such a great loss. So very sad.

In remembrance of Peer Bork  | EMBL EMBL and its community are deeply saddened by the death of Peer Bork, the organisation’s Interim Director General.

This is such hard news to process. Such an amazing scientist and inspiration for so many of us.
www.embl.org/news/embl-an...

📢 #RSCChemBio is sponsoring two poster prizes at the EMBO-EMBL Chemical Biology Workshop 2026!

📅 8 - 11th September 2026
📍 EMBL Heidelberg, Germany
🔗 www.embl.org/about/i...

Submit your abstract by 2nd June 2026 to a part of the event!

EMBO #ChemicalBiology

copyright Palina Nepachalovich of ZML Dresden

Ups we did it again! Please mark your calender. EMBO Workshop “Lipid Code to Life”, taking place September 7–11, 2026, in Dresden, organized by Maria Fedorova, @lipid.bsky.social, Valerie O'Donnell, @holthuislab.bsky.social and @molcellbiophys-lab.bsky.social 🥳 Retweets = lipidlove

Group Leader (f/m/d) at the Rudolf Virchow Center for Integrative and Translational Bioimaging - Würzburg (Stadt), Bayern (DE) job with University of Würzburg - Rudolf Virchow Center for Integrative a... The Rudolf Virchow Center for Integrative and Translational Bioimaging (RVZ) ist now inviting applications for the position of Group Leader (f/m/d).

We have an open call for a group leader at the Rudolf Virchow Center for Integrative and Translational Bioimaging in Würzburg, Germany.

Generous starting package, vibrant and highly interdisciplinary biomedical research environment.
www.nature.com/naturecareer...

Please spread the word.

Please share and spread the word!

New preprint 🥳! We made photoclickable HaloTag ligands to precisely control protein labeling on living cells. With it, we can do some cool multicolor stuff. Huge congrats to Franzi and all co-authors! Check it out 👇

www.biorxiv.org/content/10.1...

Chemical biology 2026

Registration for THE chemical biology conference of 2026 is now open! EMBO ChemBio 2026 in Heidelberg

DeGrado, Arikin, Picotti (Keynotes). @lmkdassama.bsky.social @brianliau.bsky.social @rhodamine110.bsky.social @benlehner.bsky.social @alitavassoli.bsky.social

www.embl.org/about/info/c...

Are you an early-stage graduate student (2nd or 3rd year) or early-stage postdoc based in the US or Canada, working primarily in Drosophila? Would you like to help improve the experience of all trainees working in Drosophila research? If so, read on.

(Please repost to reach a broad audience.)

I read this book when I was 15 and fell in love with DNA. I re-read it at 32 with lived experience in Science and it filled me with rage. I cannot pick up that book now. It reveals what women were/are up against.

Johnny Marr live in Cologne

Wonderful concert Sunday night in Cologne. So happy that I got to see Johnny Marr! Great crowd too!

PhD student position in the Cell Signaling and Cell Cycle group at the Danish Cancer Institute. The Cell Signaling and Cell Cycle group, headed by Prof. Jakob Nilsson, is looking for a highly motivated and enthusiastic PhD student to establish novel CRISPR

I have a PhD opening in my lab for an exiting project using base editor screens to find novel drug targets. Please help spread the word. candidate.hr-manager.net/ApplicationI...

Polo kinase inhibits protein phosphatase 1 to promote the spindle assembly checkpoint and prevent aneuploidy Protein phosphatase 1 (PP1) is essential for spindle assembly checkpoint (SAC) silencing and mitotic exit, but its regulation during mitosis remains i…

Our latest research in collaboration with @nilssonlab.bsky.social, @andrea-musacchio.bsky.social and Mathieu Bollen reveals a new regulatory strategy employed by cells to control PP1 in mitosis. Check it out in @currentbiology.bsky.social

www.sciencedirect.com/science/arti...

Congratulations, Carlos!

Epigenetics and Gene Regulation in Health and Disease: Linking Basic Mechanisms with Therapeutic Opportunities | Keystone Symposia Join us at the Keystone Symposia on Epigenetics and Gene Regulation in Health and Disease: Linking Basic Mechanisms with Therapeutic Opportunities, March 2026, in Geneva, with field leaders!

Come join us in Geneva for everything epigenetics and gene regulation. It will be a great meeting! Please repost!
www.keystonesymposia.org/conferences/...

Biological Laboratory | LEGO® Ideas This is a two-floor realistic Biological Laboratory building. In this design, I try to tell stories about biologists, introduce biology concepts to general publ…

I just made an account and voted for this biology laboratory made of LEGO to "promote biological research and inspire more people into the world of biology". They need 10K votes. Reposting and/or voting below would be helpful. 🤗
beta.ideas.lego.com/product-idea...

Congratulations! Great approach and insights! What a tremendous amount of work!

SCIMaP - Impacts of Federal Cuts to Science and Medical Research Developed by an interdisciplinary research team, this website shows how funding cuts reduce economic activity and employment nationwide

scienceimpacts.org
Please share this link widely-- it allows people to see how the loss of NIH funding will directly impact their county. Includes current impact and future impacts. It is grim. NIH funding benefits us all.

No offense taken, point came across. But there is a difference, unlike US-American scientists now, I think the Nazis deserved the “improvement”. There was support for the Nazis in Germany and fear to resist. I admire that you and others speak up openly about the nightmare, and I support if I can.