tina kim

Super proud of Isak for the sheer breadth of approaches used in this study, enabled by awesome collaborations with the Liston Lab, Hefeits Lab, Gray Lab, Nord Lab (& us!). Happy to be a part of this study!

Using 2p imaging, iGluSnFR3, and cFos validation, Isak showed that unlike 5-MeO-DMT, TBG induces neuroplasticity/neuronal activity -without- elevated glutamate release/cFos signaling in mPFC.

The psychoplastogen tabernanthalog induces neuroplasticity without proximate immediate early gene activation Nature Neuroscience - Aarrestad et al. show that, in contrast to psychedelics, the nonhallucinogenic psychoplastogen tabernanthalog promotes neuroplasticity through 5-HT2AR activation without...

Congratulations to Isak Aarrestad and Lindsay Cameron in @deolsonlab.bsky.social for a new paper published in @NatureNeuro studying mechanisms of a nonhallucinogenic psychoplastogen, TBG! rdcu.be/ey7yk