Amanda M. Buch, Ph.D.'s Avatar

Amanda M. Buch, Ph.D.

@amandambuch

Neuroscientist, AI/ML Engineer & Classical Visual Artist | Comp. Psychiatry & Neurodev. ๐Ÿง โœจ๐ŸŽจ SFARI Fellows-to-Faculty | Burroughs Wellcome Fund | Leading Edge Fellow | NASEM/Ford Fellow Weill Cornell Medicine & Columbia University www.amandabuch.com

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16.11.2024
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Latest posts by Amanda M. Buch, Ph.D. @amandambuch

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Neuroscience has a species problem If neuroscience is serious about building general principles of brain function, cross-species dialogue must become a core organizing principle.

If neuroscience is serious about building general principles of brain function, cross-species dialogue must become a core organizing principle rather than an afterthought, writes @suthanalab.bsky.social.

#neuroskyence

www.thetransmitter.org/animal-model...

16.02.2026 20:57 ๐Ÿ‘ 87 ๐Ÿ” 32 ๐Ÿ’ฌ 3 ๐Ÿ“Œ 8
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Respiration Shapes the Neural Dynamics of Successful Remembering in Humans Respiration has been shown to impact memory retrieval, yet the neural dynamics underlying this effect remain unclear. Here, we investigated how respiration shapes both behavioral and neural expression...

Respiration Shapes the Neural Dynamics of Successful Remembering in Humans

Journal of Neuroscience January 2026
#interoception #neuroskyence

www.jneurosci.org/content/46/3...

17.02.2026 20:54 ๐Ÿ‘ 22 ๐Ÿ” 7 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Why is a cross-species spinal cord taxonomy important? ๐Ÿง ๐Ÿ“ˆ

Join us on March 11 for an interactive webinar on this collaborative effort.

RSVP for link: https://alleninstitute.org/events/neuroscience-cell-types-webinars/

17.02.2026 23:41 ๐Ÿ‘ 21 ๐Ÿ” 6 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Quote card featuring UCSF neurosurgeon Doris Wang, MD, PhD. Quote: This establishes a framework for future adaptive DBS systems that could adjust stimulation in response to a patient's activity state.

Quote card featuring UCSF neurosurgeon Doris Wang, MD, PhD. Quote: This establishes a framework for future adaptive DBS systems that could adjust stimulation in response to a patient's activity state.

New in #ScienceAdvances: @doriswang.bsky.social's team shows for the first time that at-home recordings from fully implanted deep brain stimulation devices can be used to decode personalized neural biomarkers associated with gait in patients with #Parkinsons. www.ucsf.edu/news/2026/02...
๐Ÿง ๐Ÿ“ˆ ๐Ÿงช

18.02.2026 00:04 ๐Ÿ‘ 11 ๐Ÿ” 4 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Single gene sways caregiving circuits, behavior in male mice Brain levels of the agouti gene determine whether African striped mice are doting fathersโ€”or infanticidal ones.

The one gene that makes mice good dadsโ€”or infanticidal parents.

By @natmesanash.bsky.social

#neuroskyence

www.thetransmitter.org/social-behav...

18.02.2026 16:08 ๐Ÿ‘ 25 ๐Ÿ” 6 ๐Ÿ’ฌ 2 ๐Ÿ“Œ 2
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๐—•๐—ฟ๐—ฎ๐—ถ๐—ป ๐—ฝ๐—ฟ๐—ผ๐—ฐ๐—ฒ๐˜€๐˜€๐—ถ๐—ป๐—ด ๐—ถ๐˜€ ๐—ฟ๐—ฒ๐—บ๐—ฎ๐—ฟ๐—ธ๐—ฎ๐—ฏ๐—น๐˜† ๐—ฐ๐—ผ๐—ป๐˜๐—ฒ๐˜…๐˜ ๐—ฑ๐—ฒ๐—ฝ๐—ฒ๐—ป๐—ฑ๐—ฒ๐—ป๐˜
Circuits and networks can shift "computations" quite dramatically.
Check this computational model of the role of neuromodulators.
#neuroskyence
doi.org/10.1162/Neco...

18.02.2026 16:41 ๐Ÿ‘ 47 ๐Ÿ” 14 ๐Ÿ’ฌ 2 ๐Ÿ“Œ 0
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Teach neuroscience to undergraduates? Check out our "Implementing Open Neuroscience Teaching Tools" workshop!

Join us on July 19 at North Central College to get hands-on practice with inquiry-based activities using real #OpenScience resources.

๐Ÿ”— https://bit.ly/46A5j15

๐Ÿง ๐Ÿ“ˆ #iteachbio

11.02.2026 18:08 ๐Ÿ‘ 12 ๐Ÿ” 2 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 1
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Reading and writing can lower dementia risk by almost 40%, study finds Cognitive health in later life is โ€˜strongly influencedโ€™ by lifelong exposure to intellectually stimulating environments, say researchers

Reading & writing can lower dementia risk by almost 40%, study finds.

Engaging in intellectually stimulating activities throughout life was associated with a lower risk of Alzheimerโ€™s disease & slower cognitive decline.

๐Ÿงช๐Ÿง  @medsky.social #medsky #neuroskyence

www.theguardian.com/society/2026...

12.02.2026 09:19 ๐Ÿ‘ 18 ๐Ÿ” 10 ๐Ÿ’ฌ 2 ๐Ÿ“Œ 2
This is figure 1, which shose psychedelics induce brain desynchronization.

This is figure 1, which shose psychedelics induce brain desynchronization.

A Review in Nature Medicine outlines the science behind psychedelic medicine and integrates mechanistic knowledge with clinical evidence across neuropsychiatric indications, highlighting challenges, controversies and opportunities. go.nature.com/4amcefC #medsky #Neuroskyence ๐Ÿงช

12.02.2026 14:38 ๐Ÿ‘ 13 ๐Ÿ” 5 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Rhythmic sampling of multiple decision alternatives in the human brain - Nature Communications How humans process competing information when making multi-alternative decisions remains unclear. Here, the authors show that the brain resolves the trade-off between โ€œevaluating withinโ€ and โ€œcomparin...

New paper alert ๐Ÿ“ฃ #Neuroskyence

"Rhythmic sampling of multiple decision alternatives in the human brain" @natcomms.nature.com

together with @ycaoneuro.bsky.social @maryamtohidi.bsky.social @donnerlab.bsky.social @ktsetsos.bsky.social

www.nature.com/articles/s41...
๐Ÿงต1/

12.02.2026 14:41 ๐Ÿ‘ 41 ๐Ÿ” 14 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 3
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Abdus-Saboor on balancing the study of pain and pleasure David Andersonโ€™s 2013 paper revealed the sensory neurons involved in pleasurable touch and led Ishmail Abdus-Saboor down a new research path.

โ€œI like to work on problems where thereโ€™s still room to make a big impact.โ€ In โ€œThis paper changed my life,โ€ @ishmailsaboor.bsky.social discusses how a 2013 paper from David Anderson inspired him to study the circuits of pain and pleasure.

#neuroskyence

www.thetransmitter.org/this-paper-c...

13.02.2026 13:47 ๐Ÿ‘ 28 ๐Ÿ” 11 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Metadata, data documentation, and provenance Better Code, Better Science: Chapter 7, Part 8

Metadata, data documentation, and provenance
russpoldrack.substack.com/p/metadata-d... the latest in my Better Code, Better Science series.

03.02.2026 16:05 ๐Ÿ‘ 10 ๐Ÿ” 5 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Better Code, Better Science - Better Code, Better Science

For those of you who are interested, I just pushed a draft of the final chapter of Better Code, Better Science: bettercodebetterscience.github.io/book/ - now I just have to go back and rewrite the AI coding chapter which is already outdated just five months after writing it!

13.02.2026 01:04 ๐Ÿ‘ 30 ๐Ÿ” 7 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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๐Ÿ“ฃFebruary issue is live!

Cover: Intergenerational transmission of mental health

Also in this issue:
๐Ÿ‘๏ธDevelopment of spatial perception with & without vision
๐Ÿ“โž—Math anxiety in children
๐Ÿ“‹๐ŸŒMonitoring of public mental health
๐Ÿ™Ž๐Ÿง•Intergroup contact in everyday settings

Read more: go.nature.com/4rSRByT

13.02.2026 16:06 ๐Ÿ‘ 13 ๐Ÿ” 5 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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New paper alert! ๐Ÿšจ

We found that the brain's compass is remarkably stable at two scales

1๏ธโƒฃ the system maintains its internal organization for weeks
2๏ธโƒฃ It "remembers" its orientation for weeks, even after a single visit

This may be key to how the brain aligns its other maps.

Paper: rdcu.be/e3waP

11.02.2026 17:52 ๐Ÿ‘ 199 ๐Ÿ” 69 ๐Ÿ’ฌ 5 ๐Ÿ“Œ 7
Two jets, appearing red and violet, being ejected by a central protostar, hidden behind gas. The jets are extending to the left and right parts of the image. Two perpendicular thinner jets can be seen as well, coming from another protostar.

Hundreds of stars can be seen in the background of the image, appearing like bright dots with the JWST trademark diffraction spikes.

Two jets, appearing red and violet, being ejected by a central protostar, hidden behind gas. The jets are extending to the left and right parts of the image. Two perpendicular thinner jets can be seen as well, coming from another protostar. Hundreds of stars can be seen in the background of the image, appearing like bright dots with the JWST trademark diffraction spikes.

This is one of my favorite JWST observation ever! ๐Ÿ”ญ ๐Ÿ’™

This is HH288, a star heavier than the Sun being born in front of our eyes! The jets are the result of that process. There is even another star being born near it, as the perpendicular jets are showing.

HD: flic.kr/p/2rUKqvx

02.02.2026 17:08 ๐Ÿ‘ 91 ๐Ÿ” 18 ๐Ÿ’ฌ 2 ๐Ÿ“Œ 2
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Our paper is out in @natneuro.nature.com!

www.nature.com/articles/s41...

We develop a geometric theory of how neural populations support generalization across many tasks.

@zuckermanbrain.bsky.social
@flatironinstitute.org
@kempnerinstitute.bsky.social

1/14

10.02.2026 15:56 ๐Ÿ‘ 273 ๐Ÿ” 100 ๐Ÿ’ฌ 7 ๐Ÿ“Œ 1
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This complex brain network may explain many of Parkinson's stranger symptoms Parkinson's disease appears to disrupt a brain network involved in everything from movement to memory.

Parkinson's disease appears to disrupt a brain network involved in everything from movement to memory. n.pr/4kpKWtv

10.02.2026 11:03 ๐Ÿ‘ 223 ๐Ÿ” 46 ๐Ÿ’ฌ 4 ๐Ÿ“Œ 6
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The surprisingly big health benefits of just a little exercise โ€˜Exercise snacksโ€™ and other forms of everyday movement can greatly reduce the risk of heart disease and death.

A feature in Nature reports how research shows that โ€˜exercise snacksโ€™ and other forms of everyday movement can greatly reduce the risk of heart disease and death. #medsky ๐Ÿงช

01.02.2026 17:48 ๐Ÿ‘ 40 ๐Ÿ” 14 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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PIEZO channels are opening the study of mechanosensation in unexpected places The force-activated ion channels underlie the senses of touch and proprioception. Now scientists are using them as a tool to explore molecular mechanisms at work in internal organsโ€ฆ

After sketching out how PIEZO channels contribute to touch and proprioception, scientists are now using the channels as a tool to study internal organs, including the heart, bladder, uterus and kidney.

By @callimcflurry.bsky.social

#neuroskyence

www.thetransmitter.org/interoceptio...

30.01.2026 16:36 ๐Ÿ‘ 20 ๐Ÿ” 7 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 1
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A prefrontal cortex map based on single-neuron activity - Nature Neuroscience The authors mapped spontaneous and choice activity across mouse prefrontal cortex. The activity maps aligned with intrinsic connectivity rather than anatomical subregions, suggesting that connectivity, not cytoarchitecture, organizes prefrontal function.

A study in Nature Neuroscience maps spontaneous and choice activity across mouse prefrontal cortex. The activity maps aligned with intrinsic connectivity rather than anatomical subregions, suggesting that connectivity, not cytoarchitecture, organizes prefrontal function. #Neuroskyence ๐Ÿงช

01.02.2026 02:47 ๐Ÿ‘ 38 ๐Ÿ” 12 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
The centre part of a spiral galaxy where the middle is extremely bright, where the supermassive black hole is located. The middle is surrounded by rings of gas, appearing in darker coulours (mostly red and orange). Some blue gas part can be seen drifting away from the middle as the galaxy is ejecting waves of gas because of its activity.

The centre part of a spiral galaxy where the middle is extremely bright, where the supermassive black hole is located. The middle is surrounded by rings of gas, appearing in darker coulours (mostly red and orange). Some blue gas part can be seen drifting away from the middle as the galaxy is ejecting waves of gas because of its activity.

It has been a long time since I posted a picture here, so here's one to make it up! ๐Ÿ”ญ

This is the PGC 50779 galaxy, also known as the Circinus Galaxy, located some 13 million light-years away from us.

HD: flic.kr/p/2rS7tjZ

16.01.2026 15:52 ๐Ÿ‘ 43 ๐Ÿ” 8 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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๐ŸŽ‰ My PhD work has just been published in @natcomms.nature.com!

How do we learn who caused what - and how much control we had - when outcomes depend on multiple people? We studied how humans do so using a new social learning task, computational modelling and fMRI.

www.nature.com/articles/s41...
๐Ÿงต๐Ÿ‘‡

21.01.2026 13:27 ๐Ÿ‘ 52 ๐Ÿ” 19 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 2
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NeurIPS papers contained 100+ AI-hallucinated citations, new report claims | Fortune An analysis of NeurIPS 2025 papers by startup GPTZero reveals how AI-generated citations are slipping into elite academic research.

NEW: NeurIPS,one of the worldโ€™s top academic AI conferences, accepted research papers with 100+ AI-hallucinated citations, new report claims

fortune.com/2026/01/21/n...

21.01.2026 14:11 ๐Ÿ‘ 40 ๐Ÿ” 20 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 22

Wonderful work!

21.01.2026 22:04 ๐Ÿ‘ 6 ๐Ÿ” 3 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Towards a habit-rupture model of intergroup contact in everyday settings - Nature Reviews Psychology The literature assumes that intergroup contact is naturally occurring, positive and consistently associated with positive outcomes, but these premises are inconsistent with everyday intergroup contact...

#AcademicSky #PrejudiceResearch

New paper out by Paolini et al. on habit-ruptures in intergroup contact

www.nature.com/articles/s44...

(If you like that, our also team has a related paper in press at American Psychologist, led by Rose Meleady)
psycnet.apa.org/record/2026-...

21.01.2026 21:53 ๐Ÿ‘ 14 ๐Ÿ” 9 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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Perceptual clustering in auditory streaming Author summary Perceiving the world requires humans to organize perceptual stimuli according to the likely sources that generated them, requiring inference about these sources and their relationship w...

As we were celebrating psychophysics the other day, here is a fun example in the multi-source auditory domain. So beautiful. So clean. Bayes all the way. journals.plos.org/ploscompbiol...

22.01.2026 01:12 ๐Ÿ‘ 17 ๐Ÿ” 4 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

The connection between viral infection and other apparently unrelated diseases โ€” HPV โžก๏ธ cervical cancer; Epstein-Barr Virus (mono) โžก๏ธ multiple sclerosis (MS); and increasingly looking like herpes zoster (shingles) โžก๏ธ dementia โ€” is probably the most paradigm-shifting medical discovery of my lifetime. ๐Ÿงช

22.01.2026 00:43 ๐Ÿ‘ 109 ๐Ÿ” 32 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 5
Brain/MINDS Marmoset Brain Atlas 2.0: Population Cortical Parcellation With Multi-Modal Templates - Scientific Data Scientific Data - Brain/MINDS Marmoset Brain Atlas 2.0: Population Cortical Parcellation With Multi-Modal Templates

Brain/MINDS Marmoset Brain Atlas 2.0: Population Cortical Parcellation With Multi-Modal Templates | Scientific Data www.nature.com/articles/s41...

21.01.2026 23:50 ๐Ÿ‘ 11 ๐Ÿ” 7 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Part 1: How do LLMs work?
Part 1: How do LLMs work? YouTube video by Andrew Perfors

I just created a series of seven deep-dive videos about AI, which I've posted to youtube and now here. ๐Ÿ˜Š

Targeted to laypeople, they explore how LLMs work, what they can do, and what impacts they have on learning, well-being, disinformation, the workplace, the economy, and the environment.

22.01.2026 00:45 ๐Ÿ‘ 493 ๐Ÿ” 192 ๐Ÿ’ฌ 19 ๐Ÿ“Œ 18