Adam Dale

Fab study by Diane Gbesemete, @adamdale.bsky.social @jaylaver.bsky.social & the rest of the wonderful Southampton & Mali #HumanChallenge teams - a real privilege to have been involved 💙🦠🧫

Investigating immune responses to controlled human infection with Bordetella pertussis using multi-omics at University of Southampton on FindAPhD.com PhD Project - Investigating immune responses to controlled human infection with Bordetella pertussis using multi-omics at University of Southampton, listed on FindAPhD.com

🔥 PhD opportunity 🔥

Interested in a Moderna-funded PhD focused on deconvoluting the immunological mechanisms that protect against whooping cough to inform novel vaccine design with me, @afvallejo.bsky.social & @jaylaver.bsky.social?

If so, apply before 18.06.25!
www.findaphd.com/phds/project...

🔥🔥 Not an April Fool: my paper is on the *front cover* of @lancetmicrobe.bsky.social! 🤯🤯 New issue live today 🎉

Just look at that gorgeous diplococcus 😍🧫🦠👩‍🔬

Endless thanks to Chrissie Jones, Rob Read, @dbogaert.bsky.social @adamdale.bsky.social @jaylaver.bsky.social @bacterioskeptic.bsky.social

Investigating immune responses to controlled human infection with Bordetella pertussis using multi-omics at University of Southampton on FindAPhD.com PhD Project - Investigating immune responses to controlled human infection with Bordetella pertussis using multi-omics at University of Southampton, listed on FindAPhD.com

🔥 PhD opportunity 🔥

Interested in a Moderna-funded PhD focused on deconvoluting the immunological mechanisms that protect against whooping cough to inform novel vaccine design with me, @afvallejo.bsky.social & @jaylaver.bsky.social?

If so, apply before 18.06.25!
www.findaphd.com/phds/project...

I’m well thanks! Plenty of options then… I did a fair few Munros when I was in Manchester/Leeds but didn’t have kids at that stage. I haven’t done any since moving down south😭. Good luck completing that last 15.

Great effort, Patrick! What are your plans when you’ve bagged them all? Munros?

Very much looking forward to seeing the next tranche of data!

I’ll second that! This was a massive undertaking, expertly delivered by @doctoranastasia.bsky.social! Congratulations 🎉

Controlled human infection model of Neisseria lactamica in late pregnancy investigating mother-to-infant transmission in the UK: a single-arm pilot trial The infant respiratory microbiome is derived largely from the mother and is associated with downstream health and disease. Manipulating maternal respi…

Fantasitic to see achievements of the brilliant Tash Theodosiou (not on here I think) from @unisouthampton.bsky.social finally in print! With @adamdale.bsky.social @dbogaert.bsky.social Prof. Rob Read, Prof. Chrissie Jones et al. Was a pleasure to be involved!

www.sciencedirect.com/science/arti...

@ryan-elliott.bsky.social - interesting paper here for you to read and synthesise given your work using the CD154 assay!

As a first #ImmunoSky post, I’m excited to share our latest pre-print, by the fantastic Mitchell Zheng!

www.biorxiv.org/content/10.1...

Our group is interested in virus-specific CD4 T cells, which means we often use in vitro stimulations (like the AIM assay) to find our cells of interest. 🧵 1/9

Duration of infection-derived immunity to cholera - PubMed Four volunteers were rechallenged with Vibrio cholerae (10(6) classical Ogawa 395 organisms) 33-36 months after their initial induced cholera infection; none of the four veterans and four of five cont...

I’m not familiar with the GI challenge literature but it does appear similar observations were made experimentally in the 1980s. Re: duration of infection, who knows! If not humoral/systemic memory, could be TRM-related or due to subclinical infection -> boosting. pubmed.ncbi.nlm.nih.gov/7252264/

Are you London ID trainee post-PhD & interested in an ACL. May be able to create posts in 2025. Opportunities in Syphilis & STIs (UK & Global), Group A Strep (Global), Leishmaniasis & NTDs. If interested get in touch. @gpollara.bsky.social @drneilstone.bsky.social @thushan-desilva.bsky.social

@hicvac.bsky.social with Southampton Controlled Human Infection Group. Fantastic poster presentation by @alihill.bsky.social outlining T cell responses induced by the novel pertussis vaccine candidate, BPZE1 👏

Predictive gene expression signature diagnoses neonatal sepsis before clinical presentation Despite appearing healthy at birth, neonates who later developed EOS already had distinct whole blood gene expression changes at birth, which enabled the development of a 4-gene predictive signature f...

Every year, >200K newborns die from sepsis.
Our team used machine learning to develop a set of genes that can predict neonatal sepsis risk using at birth blood samples.
www.thelancet.com/journals/ebi...

This is amazing work, looking forward to sharing with colleagues @apsmunro.bsky.social

Yes please, Petter.

Hi Beth, could you add me please?

Hi Tobias, please could you add me to this list?

Hi Rod, please could you add me to the #immunology group?