Chris Brasnett

NEW on Wonkhe: Jim Dickinson examines how inaction on student finance could reshape costs, debt and access by the time that Labour faces the electorate in 2029 buff.ly/pWZ2CuY

So pleased this is finally out! Wonderful work by the incredibly talented @ma3ke.bsky.social and @janstevens.bsky.social to generate densely packed systems, even with complex topologies

Go to the paper for cool science, stay for the mesmerizing figures 🤩

Read more about it in this thread 👇

Model of mitochondrial compartments. The assembly of the mitochondrial model based on an experimentally informed membrane structure (white), from an empty structure (left) into a mask representation of the IMS (yellow) and matrix (pink) compartments represented by 3 nm voxels. Structures are packed into their assigned compartments based on the mask. In the last section and the magnified inset, structures are colored by kind: Proteins (green), RNA (dark blue), metabolites (pale blue).

Our paper about Bentopy is now published in Protein Science!

Bentopy makes assembling large-scale MD models accessible and fast.

doi.org/10.1002/pro....

@janstevens.bsky.social, @cg-martini.bsky.social

My little outlook on how our lungs 🫁 are like the sea 🌊 is finally out in Central Science. Thanks to the support from incredible mentors @rommieamaro.bsky.social and @kprather.bsky.social !!

One thing I noticed yesterday is that her long balls out from the area seemed to have less backspin than I've seen in previous games. Is there anything to back that up/could that explain some of the improvement?

Classification of containment hierarchy for point clouds in periodic space https://www.biorxiv.org/content/10.1101/2025.08.06.668936v1

Greek Tax Receipt Lottery Gives Away 10 Million Euros - The National Herald ATHENS – A Greek government scheme to cut tax cheating, a giveaway based on receipts, handed out 1000 euro ($1186)… Continue reading Greek Tax Receipt Lottery Gives Away 10 Million Euros

The Greek government does something similar already for anyone who files a tax return! www.thenationalherald.com/greek-tax-re...

The Martini 3 Lipidome: Expanded and Refined Parameters Improve Lipid Phase Behavior Lipid membranes are central to cellular life. Complementing experiments, computational modeling has been essential in unraveling complex lipid-biomolecule interactions, crucial in both academia and industry. The Martini model, a coarse-grained force field for efficient molecular dynamics simulations, is widely used to study membrane phenomena but has faced limitations, particularly in capturing realistic lipid phase behavior. Here, we present refined Martini 3 lipid models with a mapping scheme that distinguishes lipid tails that differ by just two carbon atoms, enhancing the structural resolution and thermodynamic accuracy of model membrane systems including ternary mixtures. The expanded Martini lipid library includes thousands of models, enabling simulations of complex and biologically relevant systems. These advancements establish Martini as a robust platform for lipid-based simulations across diverse fields.

Our collaborative work "The #Martini3 #Lipidome: Expanded and Refined Parameters Improve Lipid Phase Behavior" is now published in #ACSCentralScience! 🎉

📄 Read: pubs.acs.org/doi/10.1021/...

💾 GitHub: github.com/Martini-Forc...

#MolecularDynamics #Biophysics #Simulations #Lipids

The Arsenal rescuing England

Really enjoyed this post, great writing about both the Tour and Bassons!

ONE NIL TO THE ARSENAL

ARSENAL ARE THE CHAMPIONS OF EUROPE

and how is that monkey's paw you bought the other week doing?

GōMartini 3: From large conformational changes in proteins to environmental bias corrections - Nature Communications This work presents GōMartini 3, an improved coarse-grained protein model combining physics- and structure-based approaches. It boosts computational efficiency and accuracy for structured soluble and m...

GoGoGoGoGoGoGoMartini3 now finally published !
www.nature.com/articles/s41...

Pre-announcement: MARTINI tutorial workshop, August 11-15th 2025 in Groningen, The Netherlands !!
Learn basic and advanced Martini from the cocktail masters themselves. Registration will open soon.

She saw Declan Rice and really said: do it from open play

New preprint: TS2CG version 2, building and simulating membranes with any shape and lateral organisation. We got Martini Globe, Martini Möbius strip and again mitochondrion.
www.biorxiv.org/content/10.1...
@cg-martini.bsky.social @janstevens.bsky.social @fabianschuhmann.bsky.social

Thanks v much Adrien!

Happy that MartiniGlass has found a home in JCIM. I hope the tool will be useful for everyone in the user community, whether you’re trying to make nice coherent images of your system, or just make sense of instabilities!

We’re so back

Agreed with you on this before and happy to do so again! If you haven't already read it, would definitely recommend Dinner with Lenny by Jonathan Cott for a more interesting perspective on his life.

Why did the Little/Wälti substitution make such a difference this time when it’s usually so reliable?

They’ve gone for the old “a minute added on for every year this game has taken off my life” conversion

CGsmiles: A Versatile Line Notation for Molecular Representations Across Multiple Resolutions

Authors: Fabian Grünewald, Leif Seute, Riccardo Alessandri, Melanie König, Peter Kroon
DOI: 10.26434/chemrxiv-2025-vhbnq

🚀 First Bluesky Post! 🎉 VMD 2.0 Alpha is here! Released today at BPS 2025, this is the biggest update in 30 years—new UI, real-time ray tracing, fast surfaces, UHD & touchscreen support. Monthly updates coming in 2025! Try it now! #VMD #BPS2025 #MolecularVisualization
www.ks.uiuc.edu/Research/vmd...

with a natural history spin, the Naturalis museum in Leiden is curated approximately like this!

This picture >

Stinaaaaaaaaaaaa

I’m tired of hearing about bats. Do you want to hear a story about jumping spiders and the town that disappeared?

I think I might be breaking this story – do come be the first to read it.