Paolo Ciracì's Avatar

Paolo Ciracì

@paolociraci

M.D. - ESMO Research Fellow at Hospital del Mar Research Institute, Colorectal Cancer Precision Medicine Group

331
Followers
233
Following
4
Posts
23.05.2025
Joined
Posts Following

Latest posts by Paolo Ciracì @paolociraci

Post image

Final results of the PARERE Study

🩸 428 mCRC pts screened via liquid biopsy for anti-EGFR re-tx
🧬 >⅓ RAS and/or BRAF mut in ctDNA
❌ No OS diff (pani→rego vs rego→pani)
✅ Higher ORR, DCR & PFS with pani, regardless of sequence

doi.org/10.1016/j.anno…

25.10.2025 08:19 👍 1 🔁 0 💬 0 📌 0
https://www.annalsofoncology.org/article/S0923-7534(25)04934-8/fulltext

The final results of the PARERE study by GONO Foundation concomitantly published on Annals of Oncology
#ESMO25 @myesmo.bsky.social

Open Access 👉 t.co/sTomWwT8Do

18.10.2025 20:09 👍 1 🔁 0 💬 0 📌 0
Post image

#ESMOGI25: Randomised #ClinicalTrials and real-world studies in #mCRC provide further evidence in favour of anti-EGFR rechallenge, particularly with a prolonged intertreatment interval.

Read more in the #ESMODailyReporter

🔗 ow.ly/ZfB450Wl2G8

04.07.2025 14:36 👍 5 🔁 2 💬 0 📌 0
Post image Post image

First results from the PARERE trial by @FoundationGono

🩸RAS and BRAF ctDNA muts: >1/3 of mCRC patients eligible for anti-EGFR re-treatment
➡️ pani re-tx was associated with higher ORR, DCR, and longer PFS independently of the treatment sequencing

#ASCO25
@ascocancer.bsky.social

01.06.2025 17:50 👍 7 🔁 0 💬 0 📌 0
Post image

The most clinically relevant science in oncology will be presented at #ASCO25, and you can now view the full 5,000 abstracts & their presentation date, time & location info: brnw.ch/21wSRrH

22.05.2025 21:59 👍 16 🔁 10 💬 0 📌 4
Post image

Our review and evidence-based algorithm on late-line treatment options for metastatic colorectal cancer patients @natrevclinonc.nature.com

Full Article 👉 rdcu.be/d0AHE

25.05.2025 19:36 👍 15 🔁 2 💬 1 📌 0