Final results of the PARERE Study
🩸 428 mCRC pts screened via liquid biopsy for anti-EGFR re-tx
🧬 >⅓ RAS and/or BRAF mut in ctDNA
❌ No OS diff (pani→rego vs rego→pani)
✅ Higher ORR, DCR & PFS with pani, regardless of sequence
doi.org/10.1016/j.anno…
25.10.2025 08:19
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https://www.annalsofoncology.org/article/S0923-7534(25)04934-8/fulltext
The final results of the PARERE study by GONO Foundation concomitantly published on Annals of Oncology
#ESMO25 @myesmo.bsky.social
Open Access 👉 t.co/sTomWwT8Do
18.10.2025 20:09
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#ESMOGI25: Randomised #ClinicalTrials and real-world studies in #mCRC provide further evidence in favour of anti-EGFR rechallenge, particularly with a prolonged intertreatment interval.
Read more in the #ESMODailyReporter
🔗 ow.ly/ZfB450Wl2G8
04.07.2025 14:36
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First results from the PARERE trial by @FoundationGono
🩸RAS and BRAF ctDNA muts: >1/3 of mCRC patients eligible for anti-EGFR re-treatment
➡️ pani re-tx was associated with higher ORR, DCR, and longer PFS independently of the treatment sequencing
#ASCO25
@ascocancer.bsky.social
01.06.2025 17:50
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The most clinically relevant science in oncology will be presented at #ASCO25, and you can now view the full 5,000 abstracts & their presentation date, time & location info: brnw.ch/21wSRrH
22.05.2025 21:59
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Our review and evidence-based algorithm on late-line treatment options for metastatic colorectal cancer patients @natrevclinonc.nature.com
Full Article 👉 rdcu.be/d0AHE
25.05.2025 19:36
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