AnneWe

Academic employee for Research Group, Dept. of Biomedical Sciences, reNEW

Do you want to play a key role in running a cutting-edge stem cell and embryology lab at reNEW @ucph.bsky.social ? We’re hiring a Lab Manager to support our team and help with stem cell and animal work. Apply before Feb. 1st : rb.gy/d5uf17

In remembrance of Peer Bork  | EMBL EMBL and its community are deeply saddened by the death of Peer Bork, the organisation’s Interim Director General.

very sad news. Peer Bork was one of the leaders of our field, a wonderful scientist, and he's much too young to be gone. www.embl.org/news/embl-an...

60 submissions to this year's ARTxSCIENCE Competition, showcasing the work done by stem cell scientists in reNEW laboratories

#ARTxSCIENCE2025 - When #science meets art and reveals ongoing #stemcell research with the potential to transform the lives of people with so far incurable diseases. See all the beautiful entries and cast your vote for your favorite before September 22nd: renew.science/artxscience/

Mapping early human blood cell differentiation using single-cell proteomics and transcriptomics Single-cell transcriptomics (scRNA-seq) has facilitated the characterization of cell state heterogeneity and recapitulation of differentiation trajectories. However, the exclusive use of mRNA measurem...

We’re excited to present this integrative analysis of single-cell proteomics and transcriptomics of the human HSPC hierarchy. Now published in @science.org together with @fabiantheis.bsky.social, @erwinschoof.bsky.social, @porsebo.bsky.social.
www.science.org/doi/10.1126/...
🧵

It’s always a bit awkward to write about personal experiences. I tried to touch on what Pride means to me and ended up reflecting on heteronormativity, passing, and allyship. Thank you @slefkopoulos.bsky.social for the great opportunity! @ucph.bsky.social
#LGBTQIA+ #PRIDE #Diversity

α-Ketoglutarate promotes trophectoderm induction and maturation from naive human embryonic stem cells - Nature Cell Biology Van Nerum et al. show that dimethyl α-ketoglutarate enhances the production and functional maturation of human trophectoderm-like cells from embryonic stem cells by regulating histone acetyltransferas...

💫NEW: @jzylicz.bsky.social & co show that dimethyl α-ketoglutarate enhances the production and functional maturation of human #trophectoderm - like cells from embryonic #StemCells by regulating histone acetyltransferase activity and the pluripotency network.
bit.ly/3EGflmL

TCA cycle rewiring underpins implantation and histone acetylation programming Metabolism has emerged as a key regulator of stem cell differentiation and their epigenomes. This coupling is particularly evident during the exit from naive pluripotency in vitro. However, our unders...

In a new preprint with @trabelink.bsky.social, T. Moritz & @bonalditiziana.bsky.social, we find that implantation leads to rewiring of the TCA cycle to support histone acetylation turnover and exit from naïve pluripotency. Gr8 work of @elenikafkia.bsky.social D. Pladevall-Morera et al. rb.gy/clk8vm

α-Ketoglutarate promotes trophectoderm induction and maturation from naive human embryonic stem cells - Nature Cell Biology Van Nerum et al. show that dimethyl α-ketoglutarate enhances the production and functional maturation of human trophectoderm-like cells from embryonic stem cells by regulating histone acetyltransferas...

Can metabolism regulate more than bioenergetics during human development? Our new study says YES! We show that metabolism influences cell fate choice in human naïve pluripotent stem cells, histone acetylation, and trophectoderm maturation. rb.gy/spqr9j
@natcellbio.nature.com

Please RT: We are still looking for computational and/or hybrid candidates to join the lab as PhD students. Topics on Alzheimer's Diseases, cell communication and aging. e-mail me if you are interested #joboffer #PhDposition #BCN #scRNAseq

Only 2 weeks left to apply! 16 fantastic positions available, also @ucph.bsky.social . For our project remember to apply both at shorturl.at/yf7Qq & nuclear-dn.eu.

We're hiring a motivated PhD student! Join reNEW @ucph.bsky.social & @nucleardn.bsky.social to study how metabolism regulates chromatin & stem cell fate thanks to generous Marie Skłodowska-Curie Fellowship. Remember to apply both at shorturl.at/yf7Qq & nuclear-dn.eu.

I’m very excited about this collaborative project! We managed to significantly scale up and streamline human blastoid generation without the use of feeders. @leeboratory.bsky.social @grazianomartello.bsky.social @pasquelab.bsky.social and Nicolas Rivron @ucph.bsky.social

Finally on Bluesky. Running late as usual. (Plagiarizing part of my first tweet from 2015.)