Two residues reprogram immunity receptors for nitrogen-fixing symbiosis - Nature An investigation of plant receptor-like kinases identifies regions of these proteins that control whether immune or symbiotic signalling pathways are activated, with minimal changes to specific residues in one of these regions being sufficient to alter signalling specificity.

Nature research paper: Two residues reprogram immunity receptors for nitrogen-fixing symbiosis

go.nature.com/43c5b6C

Global terrestrial nitrogen fixation and its modification by agriculture - Nature Biological nitrogen fixation may impose stronger constraints on the carbon sink in natural terrestrial biomes and represent a larger source of agricultural nitrogen than is generally considered in analyses of the global nitrogen cycle.

Nature research paper: Global terrestrial nitrogen fixation and its modification by agriculture

go.nature.com/456IXUB

Design of intrinsically disordered region binding proteins Intrinsically disordered proteins and peptides play key roles in biology, but a lack of defined structures and high variability in sequence and conformational preferences have made targeting such syst...

Designed protein domains can selectively target intrinsically disordered regions, potentially generating binders for key proteins in biological function and disease. www.science.org/doi/10.1126/... #NBThighlight

Plant evolution: from origins to diversification on land The evolution of plants – photosynthetic eukaryotes resulting from the endosymbiosis of a cyanobacterium and a non-photosynthetic host cell – transformed the earth system by reducing the amount of CO…

The GMI announces a new EMBO workshop titled "Plant evolution: from origins to diversification on land" - right here in Vienna. The hybrid event will be held on November 25-27 at the Vienna BioCenter. Register by August 25 at meetings.embo.org/event/25-plant-evolution.

Two amazing opportunities at the @johninnescentre.bsky.social

So far so good in Cologne 🍀
LysM-RLKs are cool and root nodule symbiosis is important 😊
Happy to put the 🇻🇳
#2025ISMPMI

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mamp-ml: A deep learning approach to epitope immunogenicity in plants Eukaryotes detect biomolecules through surface-localized receptors, key signaling components. A subset of receptors survey for pathogens, induce immunity, and restrict pathogen growth. Comparative gen...

#2025ISMPMI 📣 In silico screening of PRR-epitope interactions is now possible!

Here, we developed mamp-ml to predict their immunogenic outcomes without structural context. Let's accelerate engineering plant receptors for robust resistance! 🚀🌱 Small 🧵

www.biorxiv.org/content/10.1...

If you are enjoying #2025ISMPMI then you might also be interested in joining the Plant Peptide and Receptor Meeting #PPRM2025, 8th-10th September in Edinburgh. We have a great lineup of speakers and a diverse and inclusive community. More info here pprm2025.events.kdmeventsportal.co.uk

Check out our new preprint! I am at P-083 at IS-MPMI, drop by for a chat :)