Jie Luo

I am honored to give a talk at #SfN and to introduce my new lab, which is developing new technologies to visualize macromolecules at the whole-body scale and to identify new targets for cancer and Alzheimer’s disease.
#SfN #Purdue #TissueClearing #DrugDiscovery #Cancer #Alzheimer

Imagine being able to visualize life-saving drugs or genetic therapies being delivered to the target cells without causing harmful side effects? Another amazing study from
@erturklab.bsky.social at @naturebiotech.bsky.social 🤩

Nanocarrier imaging at single-cell resolution across entire mouse bodies with deep learning - Nature Biotechnology An integrated experimental and deep learning pipeline reveals cell-level targeting of nanocarriers in whole bodies.

This is amazing!!! @caldaslab.bsky.social is excited about this approach to study cancer xenograft models!

Nanocarrier imaging at single-cell resolution across entire mouse bodies with deep learning - Nature Biotechnology An integrated experimental and deep learning pipeline reveals cell-level targeting of nanocarriers in whole bodies.

Nanocarrier imaging at single-cell resolution across entire mouse bodies with deep learning - @erturklab.bsky.social @hendrikdietz.bsky.social go.nature.com/4gNLjeC

And here is the skeetorial from @erturklab.bsky.social

Enjoy!

Excited to share our new technique for visualizing nanoparticles or viruses at single-cell resolution across the entire mouse body! This approach uses deep learning for precise quantification, and we’ve made the code available-give it a try with your dataset! Thanks so much to the whole team!

Look what came in the mail!!

Thanks a lot Betty.

Thanks a lot Markus! You are a great mentor supporting my project all the time!

Keep forgetting to include hashtags, like #immunosky!

My holiday gift to all of you: The editors of @science.org's favorite papers of 2024, all wrapped up nicely in this edition of #ScienceAdviser: www.science.org/content/arti... 🧪

Thrilled to share our @sciimmunology.bsky.social paper! We report that rodent PD-1 is weaker than human PD-1 (reduced ligand binding & signaling) & lacks a conserved vertebrate motif. Humanizing mouse PD-1 disrupts T cell anti-tumor responses, raising many questions. science.org/doi/10.1126/...

❤️

innocent eyes, so adorable.

Big thanks to my Postdoc and PhD mentors @erturklab.bsky.social @markuselsner.bsky.social @Farida Hellal and @Ernst Wagner for their continued support! I am also grateful to all my friends, collaborators, and colleagues!

Thrilled to share I’ll officially start next Monday as a tenure-track Assistant Professor at the Department of Industrial and Molecular Pharmaceutics, Purdue University! My lab will focus on high-precision in vivo biomedical imaging for drug discovery.